Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain

Sudden oxygenation of a thin film of rat brain homogenate, suspended between the surface of a glass pH-sensitive electrode and a gas-permeable membrane, is accompanied by a fall in pH, which is greater when carbonic anhydrase is inhibited. The result suggests that oxidative decarboxylation yields ca...

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Main Authors: Severinghaus, John W., Hamilton, F. Norman, Cotev, Shamay
Format: Text
Language:English
Published: 1969
Subjects:
Articles
Carbonic acid
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184955
http://www.ncbi.nlm.nih.gov/pubmed/4981033
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spelling ftpubmed:oai:pubmedcentral.nih.gov:1184955 2023-05-15T15:52:20+02:00 Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain Severinghaus, John W. Hamilton, F. Norman Cotev, Shamay 1969-10 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184955 http://www.ncbi.nlm.nih.gov/pubmed/4981033 en eng http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184955 http://www.ncbi.nlm.nih.gov/pubmed/4981033 Articles Text 1969 ftpubmed 2013-08-30T12:18:59Z Sudden oxygenation of a thin film of rat brain homogenate, suspended between the surface of a glass pH-sensitive electrode and a gas-permeable membrane, is accompanied by a fall in pH, which is greater when carbonic anhydrase is inhibited. The result suggests that oxidative decarboxylation yields carbonic acid (HCO3− and H+), which dissociates to form molecular carbon dioxide. Brain carbonic anhydrase facilitates the formation of carbon dioxide from the decarboxylation products. Text Carbonic acid PubMed Central (PMC)
institution Open Polar
collection PubMed Central (PMC)
op_collection_id ftpubmed
language English
topic Articles
spellingShingle Articles
Severinghaus, John W.
Hamilton, F. Norman
Cotev, Shamay
Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain
topic_facet Articles
description Sudden oxygenation of a thin film of rat brain homogenate, suspended between the surface of a glass pH-sensitive electrode and a gas-permeable membrane, is accompanied by a fall in pH, which is greater when carbonic anhydrase is inhibited. The result suggests that oxidative decarboxylation yields carbonic acid (HCO3− and H+), which dissociates to form molecular carbon dioxide. Brain carbonic anhydrase facilitates the formation of carbon dioxide from the decarboxylation products.
format Text
author Severinghaus, John W.
Hamilton, F. Norman
Cotev, Shamay
author_facet Severinghaus, John W.
Hamilton, F. Norman
Cotev, Shamay
author_sort Severinghaus, John W.
title Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain
title_short Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain
title_full Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain
title_fullStr Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain
title_full_unstemmed Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain
title_sort carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain
publishDate 1969
url http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184955
http://www.ncbi.nlm.nih.gov/pubmed/4981033
genre Carbonic acid
genre_facet Carbonic acid
op_relation http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184955
http://www.ncbi.nlm.nih.gov/pubmed/4981033
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