Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain
Sudden oxygenation of a thin film of rat brain homogenate, suspended between the surface of a glass pH-sensitive electrode and a gas-permeable membrane, is accompanied by a fall in pH, which is greater when carbonic anhydrase is inhibited. The result suggests that oxidative decarboxylation yields ca...
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ftpubmed:oai:pubmedcentral.nih.gov:1184955 2023-05-15T15:52:20+02:00 Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain Severinghaus, John W. Hamilton, F. Norman Cotev, Shamay 1969-10 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184955 http://www.ncbi.nlm.nih.gov/pubmed/4981033 en eng http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184955 http://www.ncbi.nlm.nih.gov/pubmed/4981033 Articles Text 1969 ftpubmed 2013-08-30T12:18:59Z Sudden oxygenation of a thin film of rat brain homogenate, suspended between the surface of a glass pH-sensitive electrode and a gas-permeable membrane, is accompanied by a fall in pH, which is greater when carbonic anhydrase is inhibited. The result suggests that oxidative decarboxylation yields carbonic acid (HCO3− and H+), which dissociates to form molecular carbon dioxide. Brain carbonic anhydrase facilitates the formation of carbon dioxide from the decarboxylation products. Text Carbonic acid PubMed Central (PMC) |
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Articles Severinghaus, John W. Hamilton, F. Norman Cotev, Shamay Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain |
topic_facet |
Articles |
description |
Sudden oxygenation of a thin film of rat brain homogenate, suspended between the surface of a glass pH-sensitive electrode and a gas-permeable membrane, is accompanied by a fall in pH, which is greater when carbonic anhydrase is inhibited. The result suggests that oxidative decarboxylation yields carbonic acid (HCO3− and H+), which dissociates to form molecular carbon dioxide. Brain carbonic anhydrase facilitates the formation of carbon dioxide from the decarboxylation products. |
format |
Text |
author |
Severinghaus, John W. Hamilton, F. Norman Cotev, Shamay |
author_facet |
Severinghaus, John W. Hamilton, F. Norman Cotev, Shamay |
author_sort |
Severinghaus, John W. |
title |
Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain |
title_short |
Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain |
title_full |
Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain |
title_fullStr |
Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain |
title_full_unstemmed |
Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain |
title_sort |
carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain |
publishDate |
1969 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184955 http://www.ncbi.nlm.nih.gov/pubmed/4981033 |
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Carbonic acid |
genre_facet |
Carbonic acid |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184955 http://www.ncbi.nlm.nih.gov/pubmed/4981033 |
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1766387548199845888 |