The interplay of temperature and protons in the modulation of oxygen binding by squid blood.
An extensive set of data relating to the binding of oxygen by haemocyanin from the squid Todarodes sagittatus has been collected under various experimental conditions. The results obtained show that, within the range of physiological pH, the concentration of protons affects mainly the high-affinity...
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ftpubmed:oai:pubmedcentral.nih.gov:1130751 2023-05-15T15:05:36+02:00 The interplay of temperature and protons in the modulation of oxygen binding by squid blood. Giardina, B Condò, S G Brix, O 1992-02-01 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1130751 http://www.ncbi.nlm.nih.gov/pubmed/1311173 en eng http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1130751 http://www.ncbi.nlm.nih.gov/pubmed/1311173 Research Article Text 1992 ftpubmed 2013-08-30T09:47:42Z An extensive set of data relating to the binding of oxygen by haemocyanin from the squid Todarodes sagittatus has been collected under various experimental conditions. The results obtained show that, within the range of physiological pH, the concentration of protons affects mainly the high-affinity state of the molecule without significantly affecting the low-affinity state. As far as the effect of temperature is concerned, the data show a characteristic feature which is very similar to that previously described in the case of haemoglobins from Arctic mammals such as reindeer (Rangifer tarandus) and musk ox. (Ovibos moschatus). The shape of the oxygen equilibrium curve shows strong temperature-dependence, since the overall heat of the binding of oxygen to the low-affinity state of the molecule is strongly exothermic and that to the high-affinity state is very close to zero. The results provide an outline of the intramolecular compromise that, through the interplay of temperature and protons, optimizes the loading and unloading of oxygen under the various environmental conditions experienced by this species of squid. Text Arctic musk ox ovibos moschatus Rangifer tarandus PubMed Central (PMC) Arctic |
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Research Article |
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Research Article Giardina, B Condò, S G Brix, O The interplay of temperature and protons in the modulation of oxygen binding by squid blood. |
topic_facet |
Research Article |
description |
An extensive set of data relating to the binding of oxygen by haemocyanin from the squid Todarodes sagittatus has been collected under various experimental conditions. The results obtained show that, within the range of physiological pH, the concentration of protons affects mainly the high-affinity state of the molecule without significantly affecting the low-affinity state. As far as the effect of temperature is concerned, the data show a characteristic feature which is very similar to that previously described in the case of haemoglobins from Arctic mammals such as reindeer (Rangifer tarandus) and musk ox. (Ovibos moschatus). The shape of the oxygen equilibrium curve shows strong temperature-dependence, since the overall heat of the binding of oxygen to the low-affinity state of the molecule is strongly exothermic and that to the high-affinity state is very close to zero. The results provide an outline of the intramolecular compromise that, through the interplay of temperature and protons, optimizes the loading and unloading of oxygen under the various environmental conditions experienced by this species of squid. |
format |
Text |
author |
Giardina, B Condò, S G Brix, O |
author_facet |
Giardina, B Condò, S G Brix, O |
author_sort |
Giardina, B |
title |
The interplay of temperature and protons in the modulation of oxygen binding by squid blood. |
title_short |
The interplay of temperature and protons in the modulation of oxygen binding by squid blood. |
title_full |
The interplay of temperature and protons in the modulation of oxygen binding by squid blood. |
title_fullStr |
The interplay of temperature and protons in the modulation of oxygen binding by squid blood. |
title_full_unstemmed |
The interplay of temperature and protons in the modulation of oxygen binding by squid blood. |
title_sort |
interplay of temperature and protons in the modulation of oxygen binding by squid blood. |
publishDate |
1992 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1130751 http://www.ncbi.nlm.nih.gov/pubmed/1311173 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic musk ox ovibos moschatus Rangifer tarandus |
genre_facet |
Arctic musk ox ovibos moschatus Rangifer tarandus |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1130751 http://www.ncbi.nlm.nih.gov/pubmed/1311173 |
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1766337266999885824 |