Diagnostic intervention improved health-related quality of life among teenagers with food allergy
OBJECTIVES: The aim was to examine if a diagnostic intervention set up to assess current food allergy to cow’s milk, hen’s egg, fish, or wheat among teenagers had an impact on generic and disease specific health-related quality of life (HRQL). The study compared HRQL scoring before and two years aft...
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ftpubmed:oai:pubmedcentral.nih.gov:10783743 2024-02-11T10:07:12+01:00 Diagnostic intervention improved health-related quality of life among teenagers with food allergy Hedman, Linnéa Strinnholm, Åsa Jansson, Sven-Arne Winberg, Anna 2024-01-11 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10783743/ https://doi.org/10.1371/journal.pone.0296664 en eng Public Library of Science http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10783743/ http://dx.doi.org/10.1371/journal.pone.0296664 © 2024 Hedman et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. PLoS One Research Article Text 2024 ftpubmed https://doi.org/10.1371/journal.pone.0296664 2024-01-14T02:18:07Z OBJECTIVES: The aim was to examine if a diagnostic intervention set up to assess current food allergy to cow’s milk, hen’s egg, fish, or wheat among teenagers had an impact on generic and disease specific health-related quality of life (HRQL). The study compared HRQL scoring before and two years after the intervention, and in relation to age matched controls without reported food allergy. METHODS: The study was performed within the Obstructive Lung Disease in Northern Sweden (OLIN) studies where a cohort study on asthma and allergic diseases among 8-year-old schoolchildren was initiated in 2006. At age 12 years, the 125/2612 (5%) children who reported allergy to cow’s milk, hen’s egg, fish, or wheat were invited to a diagnostic intervention including clinical examination, blood tests and evaluation by a pediatric allergist. Of 94 participants, 79 completed generic and disease specific HRQL questionnaires. Additionally, a random sample of 200 (62% of invited) children without food allergy from the OLIN cohort answered the generic HRQL questionnaire. The respondents of the HRQL questionnaires were re-examined two years later and 57 teenagers with and 154 without reported allergy participated. RESULTS: There were no significant differences in generic HRQL scores between teenagers with and without reported food allergy at study entry, or after the intervention. Among those with reported food allergy, we found a significant improvement in disease specific HRQL after the intervention (mean values: 3.41 vs 2.80, p<0.001). Teenagers with only food allergy had better disease specific HRQL compared to those with one, two or three concomitant allergic diseases, both before and after the intervention. Children with only food allergy significantly improved their HRQL after the intervention, 1.84 vs. 2.87 (p<0.001) but this association was not seen in children with one other allergic disorder (3.16 vs. 3.65, p = 0.121) or those with two or more allergic disorders (3.72 vs. 3.90, p = 0.148). CONCLUSION: The diagnostic ... Text Northern Sweden PubMed Central (PMC) PLOS ONE 19 1 e0296664 |
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Research Article Hedman, Linnéa Strinnholm, Åsa Jansson, Sven-Arne Winberg, Anna Diagnostic intervention improved health-related quality of life among teenagers with food allergy |
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Research Article |
description |
OBJECTIVES: The aim was to examine if a diagnostic intervention set up to assess current food allergy to cow’s milk, hen’s egg, fish, or wheat among teenagers had an impact on generic and disease specific health-related quality of life (HRQL). The study compared HRQL scoring before and two years after the intervention, and in relation to age matched controls without reported food allergy. METHODS: The study was performed within the Obstructive Lung Disease in Northern Sweden (OLIN) studies where a cohort study on asthma and allergic diseases among 8-year-old schoolchildren was initiated in 2006. At age 12 years, the 125/2612 (5%) children who reported allergy to cow’s milk, hen’s egg, fish, or wheat were invited to a diagnostic intervention including clinical examination, blood tests and evaluation by a pediatric allergist. Of 94 participants, 79 completed generic and disease specific HRQL questionnaires. Additionally, a random sample of 200 (62% of invited) children without food allergy from the OLIN cohort answered the generic HRQL questionnaire. The respondents of the HRQL questionnaires were re-examined two years later and 57 teenagers with and 154 without reported allergy participated. RESULTS: There were no significant differences in generic HRQL scores between teenagers with and without reported food allergy at study entry, or after the intervention. Among those with reported food allergy, we found a significant improvement in disease specific HRQL after the intervention (mean values: 3.41 vs 2.80, p<0.001). Teenagers with only food allergy had better disease specific HRQL compared to those with one, two or three concomitant allergic diseases, both before and after the intervention. Children with only food allergy significantly improved their HRQL after the intervention, 1.84 vs. 2.87 (p<0.001) but this association was not seen in children with one other allergic disorder (3.16 vs. 3.65, p = 0.121) or those with two or more allergic disorders (3.72 vs. 3.90, p = 0.148). CONCLUSION: The diagnostic ... |
format |
Text |
author |
Hedman, Linnéa Strinnholm, Åsa Jansson, Sven-Arne Winberg, Anna |
author_facet |
Hedman, Linnéa Strinnholm, Åsa Jansson, Sven-Arne Winberg, Anna |
author_sort |
Hedman, Linnéa |
title |
Diagnostic intervention improved health-related quality of life among teenagers with food allergy |
title_short |
Diagnostic intervention improved health-related quality of life among teenagers with food allergy |
title_full |
Diagnostic intervention improved health-related quality of life among teenagers with food allergy |
title_fullStr |
Diagnostic intervention improved health-related quality of life among teenagers with food allergy |
title_full_unstemmed |
Diagnostic intervention improved health-related quality of life among teenagers with food allergy |
title_sort |
diagnostic intervention improved health-related quality of life among teenagers with food allergy |
publisher |
Public Library of Science |
publishDate |
2024 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10783743/ https://doi.org/10.1371/journal.pone.0296664 |
genre |
Northern Sweden |
genre_facet |
Northern Sweden |
op_source |
PLoS One |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10783743/ http://dx.doi.org/10.1371/journal.pone.0296664 |
op_rights |
© 2024 Hedman et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
op_doi |
https://doi.org/10.1371/journal.pone.0296664 |
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PLOS ONE |
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19 |
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