Application of novel burst wave lithotripsy and ultrasonic propulsion technology for the treatment of ureteral calculi in a bottlenose dolphin (Tursiops truncatus) and renal calculi in a harbor seal (Phoca vitulina)
Marine mammals may develop kidney stones, which can be challenging to treat. We describe burst wave lithotripsy (BWL) and ultrasonic propulsion to treat ureteral calculi in a 48-year-old female bottlenose dolphin (Tursiops truncatus) and to reduce renal stone burden in a 23-year-old male harbor seal...
Published in: | Urolithiasis |
---|---|
Main Authors: | , , , , , , , , , , , , , , , , , |
Format: | Text |
Language: | English |
Published: |
Springer Berlin Heidelberg
2024
|
Subjects: | |
Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10774161/ http://www.ncbi.nlm.nih.gov/pubmed/38189835 https://doi.org/10.1007/s00240-023-01515-6 |
id |
ftpubmed:oai:pubmedcentral.nih.gov:10774161 |
---|---|
record_format |
openpolar |
spelling |
ftpubmed:oai:pubmedcentral.nih.gov:10774161 2024-02-11T10:04:32+01:00 Application of novel burst wave lithotripsy and ultrasonic propulsion technology for the treatment of ureteral calculi in a bottlenose dolphin (Tursiops truncatus) and renal calculi in a harbor seal (Phoca vitulina) Holmes, Arturo E. Chew, Ben H. Laughlin, Robert Buckley, Jean Kiewice, Erica Dancel, Michael J. Blasko, David Wong, Victor K. F. Halawani, Abdulghafour Koo, Kyo Chul Corl, Doug Fasolo, Paul Levy, Oren Thiel, Jeff Bailey, Michael R. Eichman, Jammy Meegan, Jennifer M. Haulena, Martin 2024-01-08 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10774161/ http://www.ncbi.nlm.nih.gov/pubmed/38189835 https://doi.org/10.1007/s00240-023-01515-6 en eng Springer Berlin Heidelberg http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10774161/ http://www.ncbi.nlm.nih.gov/pubmed/38189835 http://dx.doi.org/10.1007/s00240-023-01515-6 © The Author(s) 2024 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . Urolithiasis Research Text 2024 ftpubmed https://doi.org/10.1007/s00240-023-01515-6 2024-01-14T01:56:48Z Marine mammals may develop kidney stones, which can be challenging to treat. We describe burst wave lithotripsy (BWL) and ultrasonic propulsion to treat ureteral calculi in a 48-year-old female bottlenose dolphin (Tursiops truncatus) and to reduce renal stone burden in a 23-year-old male harbor seal (Phoca vitulina). BWL and ultrasonic propulsion were delivered transcutaneously in sinusoidal ultrasound bursts to fragment and reposition stones. Targeting and monitoring were performed with real-time imaging integrated within the BWL system. Four dolphin stones were obtained and fragmented ex vivo. The dolphin case received a 10-min and a 20-min BWL treatment conducted approximately 24 h apart to treat two 8–10 mm partially obstructing right mid-ureteral stones, using oral sedation alone. For the harbor seal, while under general anesthesia, retrograde ureteroscopy attempts were unsuccessful because of ureteral tortuosity, and a 30-min BWL treatment was targeted on one 10-mm right kidney stone cluster. All 4 stones fragmented completely to < 2-mm fragments in < 20 min ex vivo. In the dolphin case, the ureteral stones appeared to fragment, spread apart, and move with ultrasonic propulsion. On post-treatment day 1, the ureteral calculi fragments shifted caudally reaching the ureteral orifice on day 9. On day 10, the calculi fragments passed, and the hydroureter resolved. In the harbor seal, the stone cluster was observed to fragment and was not visible on the post-operative computed tomography scan. The seal had gross hematuria and a day of behavior indicating stone passage but overall, an uneventful recovery. BWL and ultrasonic propulsion successfully relieved ureteral stone obstruction in a geriatric dolphin and reduced renal stone burden in a geriatric harbor seal. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00240-023-01515-6. Text harbor seal Phoca vitulina PubMed Central (PMC) Urolithiasis 52 1 |
institution |
Open Polar |
collection |
PubMed Central (PMC) |
op_collection_id |
ftpubmed |
language |
English |
topic |
Research |
spellingShingle |
Research Holmes, Arturo E. Chew, Ben H. Laughlin, Robert Buckley, Jean Kiewice, Erica Dancel, Michael J. Blasko, David Wong, Victor K. F. Halawani, Abdulghafour Koo, Kyo Chul Corl, Doug Fasolo, Paul Levy, Oren Thiel, Jeff Bailey, Michael R. Eichman, Jammy Meegan, Jennifer M. Haulena, Martin Application of novel burst wave lithotripsy and ultrasonic propulsion technology for the treatment of ureteral calculi in a bottlenose dolphin (Tursiops truncatus) and renal calculi in a harbor seal (Phoca vitulina) |
topic_facet |
Research |
description |
Marine mammals may develop kidney stones, which can be challenging to treat. We describe burst wave lithotripsy (BWL) and ultrasonic propulsion to treat ureteral calculi in a 48-year-old female bottlenose dolphin (Tursiops truncatus) and to reduce renal stone burden in a 23-year-old male harbor seal (Phoca vitulina). BWL and ultrasonic propulsion were delivered transcutaneously in sinusoidal ultrasound bursts to fragment and reposition stones. Targeting and monitoring were performed with real-time imaging integrated within the BWL system. Four dolphin stones were obtained and fragmented ex vivo. The dolphin case received a 10-min and a 20-min BWL treatment conducted approximately 24 h apart to treat two 8–10 mm partially obstructing right mid-ureteral stones, using oral sedation alone. For the harbor seal, while under general anesthesia, retrograde ureteroscopy attempts were unsuccessful because of ureteral tortuosity, and a 30-min BWL treatment was targeted on one 10-mm right kidney stone cluster. All 4 stones fragmented completely to < 2-mm fragments in < 20 min ex vivo. In the dolphin case, the ureteral stones appeared to fragment, spread apart, and move with ultrasonic propulsion. On post-treatment day 1, the ureteral calculi fragments shifted caudally reaching the ureteral orifice on day 9. On day 10, the calculi fragments passed, and the hydroureter resolved. In the harbor seal, the stone cluster was observed to fragment and was not visible on the post-operative computed tomography scan. The seal had gross hematuria and a day of behavior indicating stone passage but overall, an uneventful recovery. BWL and ultrasonic propulsion successfully relieved ureteral stone obstruction in a geriatric dolphin and reduced renal stone burden in a geriatric harbor seal. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00240-023-01515-6. |
format |
Text |
author |
Holmes, Arturo E. Chew, Ben H. Laughlin, Robert Buckley, Jean Kiewice, Erica Dancel, Michael J. Blasko, David Wong, Victor K. F. Halawani, Abdulghafour Koo, Kyo Chul Corl, Doug Fasolo, Paul Levy, Oren Thiel, Jeff Bailey, Michael R. Eichman, Jammy Meegan, Jennifer M. Haulena, Martin |
author_facet |
Holmes, Arturo E. Chew, Ben H. Laughlin, Robert Buckley, Jean Kiewice, Erica Dancel, Michael J. Blasko, David Wong, Victor K. F. Halawani, Abdulghafour Koo, Kyo Chul Corl, Doug Fasolo, Paul Levy, Oren Thiel, Jeff Bailey, Michael R. Eichman, Jammy Meegan, Jennifer M. Haulena, Martin |
author_sort |
Holmes, Arturo E. |
title |
Application of novel burst wave lithotripsy and ultrasonic propulsion technology for the treatment of ureteral calculi in a bottlenose dolphin (Tursiops truncatus) and renal calculi in a harbor seal (Phoca vitulina) |
title_short |
Application of novel burst wave lithotripsy and ultrasonic propulsion technology for the treatment of ureteral calculi in a bottlenose dolphin (Tursiops truncatus) and renal calculi in a harbor seal (Phoca vitulina) |
title_full |
Application of novel burst wave lithotripsy and ultrasonic propulsion technology for the treatment of ureteral calculi in a bottlenose dolphin (Tursiops truncatus) and renal calculi in a harbor seal (Phoca vitulina) |
title_fullStr |
Application of novel burst wave lithotripsy and ultrasonic propulsion technology for the treatment of ureteral calculi in a bottlenose dolphin (Tursiops truncatus) and renal calculi in a harbor seal (Phoca vitulina) |
title_full_unstemmed |
Application of novel burst wave lithotripsy and ultrasonic propulsion technology for the treatment of ureteral calculi in a bottlenose dolphin (Tursiops truncatus) and renal calculi in a harbor seal (Phoca vitulina) |
title_sort |
application of novel burst wave lithotripsy and ultrasonic propulsion technology for the treatment of ureteral calculi in a bottlenose dolphin (tursiops truncatus) and renal calculi in a harbor seal (phoca vitulina) |
publisher |
Springer Berlin Heidelberg |
publishDate |
2024 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10774161/ http://www.ncbi.nlm.nih.gov/pubmed/38189835 https://doi.org/10.1007/s00240-023-01515-6 |
genre |
harbor seal Phoca vitulina |
genre_facet |
harbor seal Phoca vitulina |
op_source |
Urolithiasis |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10774161/ http://www.ncbi.nlm.nih.gov/pubmed/38189835 http://dx.doi.org/10.1007/s00240-023-01515-6 |
op_rights |
© The Author(s) 2024 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
op_doi |
https://doi.org/10.1007/s00240-023-01515-6 |
container_title |
Urolithiasis |
container_volume |
52 |
container_issue |
1 |
_version_ |
1790601165886455808 |