Uptake and availability of new outpatient cancer medicines in 2010–2021 in Nordic countries – survey of competent authorities
BACKGROUND: Nordic countries excel in cancer care, but studies on uptake, costs, or managed entry agreements of cancer medicines have not been conducted recently. The aim of this study was to examine the uptake and availability of orally administered new cancer medicines in Nordic countries. Orally...
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ftpubmed:oai:pubmedcentral.nih.gov:10729379 2024-01-21T10:07:15+01:00 Uptake and availability of new outpatient cancer medicines in 2010–2021 in Nordic countries – survey of competent authorities Sarnola, Kati Koskinen, Hanna Klintrup, Katariina Astrup, Cecilie Kurko, Terhi 2023-12-18 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10729379/ http://www.ncbi.nlm.nih.gov/pubmed/38110924 https://doi.org/10.1186/s12913-023-10421-x en eng BioMed Central http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10729379/ http://www.ncbi.nlm.nih.gov/pubmed/38110924 http://dx.doi.org/10.1186/s12913-023-10421-x © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. BMC Health Serv Res Research Text 2023 ftpubmed https://doi.org/10.1186/s12913-023-10421-x 2023-12-24T02:00:48Z BACKGROUND: Nordic countries excel in cancer care, but studies on uptake, costs, or managed entry agreements of cancer medicines have not been conducted recently. The aim of this study was to examine the uptake and availability of orally administered new cancer medicines in Nordic countries. Orally administered cancer medicines enable and are used in the community as part of outpatient care. Firstly, we studied the distribution, costs and adoption of managed entry agreements of these medicines, and secondly, uptake of and managed entry agreements for cancer medicines used in outpatient care that were granted marketing authorization in Europe in 2010–2021. METHODS: An E-mail survey of competent authorities, meaning pharmaceutical service organizers, payers or other government or non-government actors developing pharmaceutical service operations, in Denmark, Finland, Iceland, Norway, and Sweden in April-June 2022. The data were analysed using frequencies and percentages for descriptive analysis. RESULTS: The distribution of cancer medicines has similarities in Finland, Iceland, Norway, and Sweden, where cancer medicines can be distributed both via hospitals or hospital pharmacies for inpatient use, and via community pharmacies for outpatient use. In Denmark, cancer medicines are predominantly distributed via publicly funded hospitals. In all countries that provided data on the costs, the costs of cancer medicines had notably gone up from 2010 to 2021. The number of reimbursable medicines out of new cancer medicines varied from 36 products in Denmark and Iceland to 51 products in Sweden, out of 67 studied products. Managed entry agreements, often with confidential discounts, were in use in all Nordic countries. The number of agreements and the cancer types for which agreements were most often made varied from three agreements made in Iceland to 35 agreements made in Finland, out of 67 studied products. Average days from authorization to reimbursement of new cancer medicines varied from an average of 416 to 895 ... Text Iceland PubMed Central (PMC) Norway BMC Health Services Research 23 1 |
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Research Sarnola, Kati Koskinen, Hanna Klintrup, Katariina Astrup, Cecilie Kurko, Terhi Uptake and availability of new outpatient cancer medicines in 2010–2021 in Nordic countries – survey of competent authorities |
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Research |
description |
BACKGROUND: Nordic countries excel in cancer care, but studies on uptake, costs, or managed entry agreements of cancer medicines have not been conducted recently. The aim of this study was to examine the uptake and availability of orally administered new cancer medicines in Nordic countries. Orally administered cancer medicines enable and are used in the community as part of outpatient care. Firstly, we studied the distribution, costs and adoption of managed entry agreements of these medicines, and secondly, uptake of and managed entry agreements for cancer medicines used in outpatient care that were granted marketing authorization in Europe in 2010–2021. METHODS: An E-mail survey of competent authorities, meaning pharmaceutical service organizers, payers or other government or non-government actors developing pharmaceutical service operations, in Denmark, Finland, Iceland, Norway, and Sweden in April-June 2022. The data were analysed using frequencies and percentages for descriptive analysis. RESULTS: The distribution of cancer medicines has similarities in Finland, Iceland, Norway, and Sweden, where cancer medicines can be distributed both via hospitals or hospital pharmacies for inpatient use, and via community pharmacies for outpatient use. In Denmark, cancer medicines are predominantly distributed via publicly funded hospitals. In all countries that provided data on the costs, the costs of cancer medicines had notably gone up from 2010 to 2021. The number of reimbursable medicines out of new cancer medicines varied from 36 products in Denmark and Iceland to 51 products in Sweden, out of 67 studied products. Managed entry agreements, often with confidential discounts, were in use in all Nordic countries. The number of agreements and the cancer types for which agreements were most often made varied from three agreements made in Iceland to 35 agreements made in Finland, out of 67 studied products. Average days from authorization to reimbursement of new cancer medicines varied from an average of 416 to 895 ... |
format |
Text |
author |
Sarnola, Kati Koskinen, Hanna Klintrup, Katariina Astrup, Cecilie Kurko, Terhi |
author_facet |
Sarnola, Kati Koskinen, Hanna Klintrup, Katariina Astrup, Cecilie Kurko, Terhi |
author_sort |
Sarnola, Kati |
title |
Uptake and availability of new outpatient cancer medicines in 2010–2021 in Nordic countries – survey of competent authorities |
title_short |
Uptake and availability of new outpatient cancer medicines in 2010–2021 in Nordic countries – survey of competent authorities |
title_full |
Uptake and availability of new outpatient cancer medicines in 2010–2021 in Nordic countries – survey of competent authorities |
title_fullStr |
Uptake and availability of new outpatient cancer medicines in 2010–2021 in Nordic countries – survey of competent authorities |
title_full_unstemmed |
Uptake and availability of new outpatient cancer medicines in 2010–2021 in Nordic countries – survey of competent authorities |
title_sort |
uptake and availability of new outpatient cancer medicines in 2010–2021 in nordic countries – survey of competent authorities |
publisher |
BioMed Central |
publishDate |
2023 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10729379/ http://www.ncbi.nlm.nih.gov/pubmed/38110924 https://doi.org/10.1186/s12913-023-10421-x |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
BMC Health Serv Res |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10729379/ http://www.ncbi.nlm.nih.gov/pubmed/38110924 http://dx.doi.org/10.1186/s12913-023-10421-x |
op_rights |
© The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
op_doi |
https://doi.org/10.1186/s12913-023-10421-x |
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BMC Health Services Research |
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23 |
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