Cardiovascular and Metabolic Profile of Subjects with Acne in a Cohort of Middle-aged Patients: A General Population Study of 1,932 Subjects
Acne vulgaris is one of the most common inflammatory skin diseases, but there are few studies of adult acne and its association with general health. The aim of this study was to examine the prevalence and clinical characteristics of adult acne at the population level among 1,932 subjects belonging t...
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Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339821/ http://www.ncbi.nlm.nih.gov/pubmed/37428028 https://doi.org/10.2340/actadv.v103.5921 |
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ftpubmed:oai:pubmedcentral.nih.gov:10339821 2023-07-30T04:05:49+02:00 Cardiovascular and Metabolic Profile of Subjects with Acne in a Cohort of Middle-aged Patients: A General Population Study of 1,932 Subjects SINIKUMPU, Suvi-Päivikki JOKELAINEN, Jari TASANEN, Kaisa HUILAJA, Laura 2023-07-10 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339821/ http://www.ncbi.nlm.nih.gov/pubmed/37428028 https://doi.org/10.2340/actadv.v103.5921 en eng Medical Journals Sweden, on behalf of the Society for Publication of Acta Dermato-Venereologica http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339821/ http://www.ncbi.nlm.nih.gov/pubmed/37428028 http://dx.doi.org/10.2340/actadv.v103.5921 © 2023 Acta Dermato-Venereologica https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License Acta Derm Venereol Original Report Text 2023 ftpubmed https://doi.org/10.2340/actadv.v103.5921 2023-07-16T01:10:01Z Acne vulgaris is one of the most common inflammatory skin diseases, but there are few studies of adult acne and its association with general health. The aim of this study was to examine the prevalence and clinical characteristics of adult acne at the population level among 1,932 subjects belonging to the Northern Finland Birth Cohort 1966 Study. In addition, cardiovascular and metabolic profiles of acne cases and their controls were analysed. The prevalence of adult acne was 7.9% (n = 150) with no statistical difference between the sexes. The majority of subjects presented with papulopustular acne (77.1%). Comedo acne (10.8% of all subjects) was more common in females than in males (p < 0.005). Males with acne had more abnormality in their metabolic factors than did acne-free controls; plasma glucose and insulin levels at 60 min after the 75 g glucose load were higher in males with acne than in controls (p < 0.01 for both). Corresponding associations were not seen in females. In conclusion, adult acne is common in middle-age, presenting a slightly different clinical picture in females than in males. In addition, male subjects with acne may have a higher risk of metabolic disturbances than do controls, and thus, comprehensive evaluation of patients with adult acne is needed. SIGNIFICANCE Many patients experience acne after adolescence. However, there are few studies of adult acne. The aim of this study was to examine the prevalence of acne in the general population belonging to the Northern Finland Birth Cohort 1966 Study at the age of 46 years (n = 1,932). Acne was found to be common in middle-age; it was present in 7.9% of cases (n = 150). The most common type of adult acne was papulopustular acne, but comedo acne was also seen. Moreover, the study found that males with acne had more metabolic abnormalities, such as differences in insulin and glucose secretion, compared with acne-free controls. Text Northern Finland PubMed Central (PMC) Acta Dermato-Venereologica 103 adv5921 |
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Original Report SINIKUMPU, Suvi-Päivikki JOKELAINEN, Jari TASANEN, Kaisa HUILAJA, Laura Cardiovascular and Metabolic Profile of Subjects with Acne in a Cohort of Middle-aged Patients: A General Population Study of 1,932 Subjects |
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Original Report |
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Acne vulgaris is one of the most common inflammatory skin diseases, but there are few studies of adult acne and its association with general health. The aim of this study was to examine the prevalence and clinical characteristics of adult acne at the population level among 1,932 subjects belonging to the Northern Finland Birth Cohort 1966 Study. In addition, cardiovascular and metabolic profiles of acne cases and their controls were analysed. The prevalence of adult acne was 7.9% (n = 150) with no statistical difference between the sexes. The majority of subjects presented with papulopustular acne (77.1%). Comedo acne (10.8% of all subjects) was more common in females than in males (p < 0.005). Males with acne had more abnormality in their metabolic factors than did acne-free controls; plasma glucose and insulin levels at 60 min after the 75 g glucose load were higher in males with acne than in controls (p < 0.01 for both). Corresponding associations were not seen in females. In conclusion, adult acne is common in middle-age, presenting a slightly different clinical picture in females than in males. In addition, male subjects with acne may have a higher risk of metabolic disturbances than do controls, and thus, comprehensive evaluation of patients with adult acne is needed. SIGNIFICANCE Many patients experience acne after adolescence. However, there are few studies of adult acne. The aim of this study was to examine the prevalence of acne in the general population belonging to the Northern Finland Birth Cohort 1966 Study at the age of 46 years (n = 1,932). Acne was found to be common in middle-age; it was present in 7.9% of cases (n = 150). The most common type of adult acne was papulopustular acne, but comedo acne was also seen. Moreover, the study found that males with acne had more metabolic abnormalities, such as differences in insulin and glucose secretion, compared with acne-free controls. |
format |
Text |
author |
SINIKUMPU, Suvi-Päivikki JOKELAINEN, Jari TASANEN, Kaisa HUILAJA, Laura |
author_facet |
SINIKUMPU, Suvi-Päivikki JOKELAINEN, Jari TASANEN, Kaisa HUILAJA, Laura |
author_sort |
SINIKUMPU, Suvi-Päivikki |
title |
Cardiovascular and Metabolic Profile of Subjects with Acne in a Cohort of Middle-aged Patients: A General Population Study of 1,932 Subjects |
title_short |
Cardiovascular and Metabolic Profile of Subjects with Acne in a Cohort of Middle-aged Patients: A General Population Study of 1,932 Subjects |
title_full |
Cardiovascular and Metabolic Profile of Subjects with Acne in a Cohort of Middle-aged Patients: A General Population Study of 1,932 Subjects |
title_fullStr |
Cardiovascular and Metabolic Profile of Subjects with Acne in a Cohort of Middle-aged Patients: A General Population Study of 1,932 Subjects |
title_full_unstemmed |
Cardiovascular and Metabolic Profile of Subjects with Acne in a Cohort of Middle-aged Patients: A General Population Study of 1,932 Subjects |
title_sort |
cardiovascular and metabolic profile of subjects with acne in a cohort of middle-aged patients: a general population study of 1,932 subjects |
publisher |
Medical Journals Sweden, on behalf of the Society for Publication of Acta Dermato-Venereologica |
publishDate |
2023 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339821/ http://www.ncbi.nlm.nih.gov/pubmed/37428028 https://doi.org/10.2340/actadv.v103.5921 |
genre |
Northern Finland |
genre_facet |
Northern Finland |
op_source |
Acta Derm Venereol |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339821/ http://www.ncbi.nlm.nih.gov/pubmed/37428028 http://dx.doi.org/10.2340/actadv.v103.5921 |
op_rights |
© 2023 Acta Dermato-Venereologica https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License |
op_doi |
https://doi.org/10.2340/actadv.v103.5921 |
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Acta Dermato-Venereologica |
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103 |
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adv5921 |
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