New Vectors of TTX Analogues in the North Atlantic Coast: The Edible Crabs Afruca tangeri and Carcinus maenas
Tetrodotoxin (TTX) and its analogues are naturally occurring toxins historically responsible for human poisoning fatalities in Eastern Asia. It is typically linked to the consumption of pufferfish and, to a lesser extent, marine gastropods and crabs. In the scope of a comprehensive project to unders...
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ftpubmed:oai:pubmedcentral.nih.gov:10305652 2023-07-23T04:20:40+02:00 New Vectors of TTX Analogues in the North Atlantic Coast: The Edible Crabs Afruca tangeri and Carcinus maenas Lage, Sandra ten Brink, Felicitas Canário, Adelino V. M. Da Silva, José P. 2023-05-25 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305652/ http://www.ncbi.nlm.nih.gov/pubmed/37367645 https://doi.org/10.3390/md21060320 en eng MDPI http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305652/ http://www.ncbi.nlm.nih.gov/pubmed/37367645 http://dx.doi.org/10.3390/md21060320 © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Mar Drugs Article Text 2023 ftpubmed https://doi.org/10.3390/md21060320 2023-07-02T01:28:31Z Tetrodotoxin (TTX) and its analogues are naturally occurring toxins historically responsible for human poisoning fatalities in Eastern Asia. It is typically linked to the consumption of pufferfish and, to a lesser extent, marine gastropods and crabs. In the scope of a comprehensive project to understand the prevalence of emergent toxins in edible marine organisms, we report, for the first time, the detection of TTX analogues in the soft tissues of edible crabs, the European fiddler crab (Afruca tangeri) and green crab (Carcinus maenas), harvested in southern Portugal. No TTX was detected in the analyzed samples. However, three TTX analogues were detected—an unknown TTX epimer, deoxyTTX, and trideoxyTTX. These three analogues were found in the European fiddler crab while only trideoxyTTX was found in the green crab, suggesting that the accumulation of TTX analogues might be influenced by the crabs’ different feeding ecology. These results highlight the need to widely monitor TTX and its analogues in edible marine species in order to provide adequate information to the European Food Safety Authority and to protect consumers. Text North Atlantic PubMed Central (PMC) Marine Drugs 21 6 320 |
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Article Lage, Sandra ten Brink, Felicitas Canário, Adelino V. M. Da Silva, José P. New Vectors of TTX Analogues in the North Atlantic Coast: The Edible Crabs Afruca tangeri and Carcinus maenas |
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Tetrodotoxin (TTX) and its analogues are naturally occurring toxins historically responsible for human poisoning fatalities in Eastern Asia. It is typically linked to the consumption of pufferfish and, to a lesser extent, marine gastropods and crabs. In the scope of a comprehensive project to understand the prevalence of emergent toxins in edible marine organisms, we report, for the first time, the detection of TTX analogues in the soft tissues of edible crabs, the European fiddler crab (Afruca tangeri) and green crab (Carcinus maenas), harvested in southern Portugal. No TTX was detected in the analyzed samples. However, three TTX analogues were detected—an unknown TTX epimer, deoxyTTX, and trideoxyTTX. These three analogues were found in the European fiddler crab while only trideoxyTTX was found in the green crab, suggesting that the accumulation of TTX analogues might be influenced by the crabs’ different feeding ecology. These results highlight the need to widely monitor TTX and its analogues in edible marine species in order to provide adequate information to the European Food Safety Authority and to protect consumers. |
format |
Text |
author |
Lage, Sandra ten Brink, Felicitas Canário, Adelino V. M. Da Silva, José P. |
author_facet |
Lage, Sandra ten Brink, Felicitas Canário, Adelino V. M. Da Silva, José P. |
author_sort |
Lage, Sandra |
title |
New Vectors of TTX Analogues in the North Atlantic Coast: The Edible Crabs Afruca tangeri and Carcinus maenas |
title_short |
New Vectors of TTX Analogues in the North Atlantic Coast: The Edible Crabs Afruca tangeri and Carcinus maenas |
title_full |
New Vectors of TTX Analogues in the North Atlantic Coast: The Edible Crabs Afruca tangeri and Carcinus maenas |
title_fullStr |
New Vectors of TTX Analogues in the North Atlantic Coast: The Edible Crabs Afruca tangeri and Carcinus maenas |
title_full_unstemmed |
New Vectors of TTX Analogues in the North Atlantic Coast: The Edible Crabs Afruca tangeri and Carcinus maenas |
title_sort |
new vectors of ttx analogues in the north atlantic coast: the edible crabs afruca tangeri and carcinus maenas |
publisher |
MDPI |
publishDate |
2023 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305652/ http://www.ncbi.nlm.nih.gov/pubmed/37367645 https://doi.org/10.3390/md21060320 |
genre |
North Atlantic |
genre_facet |
North Atlantic |
op_source |
Mar Drugs |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305652/ http://www.ncbi.nlm.nih.gov/pubmed/37367645 http://dx.doi.org/10.3390/md21060320 |
op_rights |
© 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
op_doi |
https://doi.org/10.3390/md21060320 |
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Marine Drugs |
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21 |
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6 |
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320 |
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1772185263389278208 |