Unique evolution of foraminiferal calcification to survive global changes
Foraminifera, the most ancient known calcium carbonate–producing eukaryotes, are crucial players in global biogeochemical cycles and well-used environmental indicators in biogeosciences. However, little is known about their calcification mechanisms. This impedes understanding the organismal response...
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ftpubmed:oai:pubmedcentral.nih.gov:10284544 2023-07-16T04:00:16+02:00 Unique evolution of foraminiferal calcification to survive global changes Ujiié, Yurika Ishitani, Yoshiyuki Nagai, Yukiko Takaki, Yoshihiro Toyofuku, Takashi Ishii, Shun’ichi 2023-06-21 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284544/ https://doi.org/10.1126/sciadv.add3584 en eng American Association for the Advancement of Science http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284544/ http://dx.doi.org/10.1126/sciadv.add3584 Copyright © 2023 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY). https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Sci Adv Biomedicine and Life Sciences Text 2023 ftpubmed https://doi.org/10.1126/sciadv.add3584 2023-06-25T01:05:15Z Foraminifera, the most ancient known calcium carbonate–producing eukaryotes, are crucial players in global biogeochemical cycles and well-used environmental indicators in biogeosciences. However, little is known about their calcification mechanisms. This impedes understanding the organismal responses to ocean acidification, which alters marine calcium carbonate production, potentially leading to biogeochemical cycle changes. We conducted comparative single-cell transcriptomics and fluorescent microscopy and identified calcium ion (Ca(2+)) transport/secretion genes and α-carbonic anhydrases that control calcification in a foraminifer. They actively take up Ca(2+) to boost mitochondrial adenosine triphosphate synthesis during calcification but need to pump excess intracellular Ca(2+) to the calcification site to prevent cell death. Unique α-carbonic anhydrase genes induce the generation of bicarbonate and proton from multiple CO(2) sources. These control mechanisms have evolved independently since the Precambrian to enable the development of large cells and calcification despite decreasing Ca(2+) concentrations and pH in seawater. The present findings provide previously unknown insights into the calcification mechanisms and their subsequent function in enduring ocean acidification. Text Ocean acidification PubMed Central (PMC) Science Advances 9 25 |
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English |
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Biomedicine and Life Sciences |
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Biomedicine and Life Sciences Ujiié, Yurika Ishitani, Yoshiyuki Nagai, Yukiko Takaki, Yoshihiro Toyofuku, Takashi Ishii, Shun’ichi Unique evolution of foraminiferal calcification to survive global changes |
topic_facet |
Biomedicine and Life Sciences |
description |
Foraminifera, the most ancient known calcium carbonate–producing eukaryotes, are crucial players in global biogeochemical cycles and well-used environmental indicators in biogeosciences. However, little is known about their calcification mechanisms. This impedes understanding the organismal responses to ocean acidification, which alters marine calcium carbonate production, potentially leading to biogeochemical cycle changes. We conducted comparative single-cell transcriptomics and fluorescent microscopy and identified calcium ion (Ca(2+)) transport/secretion genes and α-carbonic anhydrases that control calcification in a foraminifer. They actively take up Ca(2+) to boost mitochondrial adenosine triphosphate synthesis during calcification but need to pump excess intracellular Ca(2+) to the calcification site to prevent cell death. Unique α-carbonic anhydrase genes induce the generation of bicarbonate and proton from multiple CO(2) sources. These control mechanisms have evolved independently since the Precambrian to enable the development of large cells and calcification despite decreasing Ca(2+) concentrations and pH in seawater. The present findings provide previously unknown insights into the calcification mechanisms and their subsequent function in enduring ocean acidification. |
format |
Text |
author |
Ujiié, Yurika Ishitani, Yoshiyuki Nagai, Yukiko Takaki, Yoshihiro Toyofuku, Takashi Ishii, Shun’ichi |
author_facet |
Ujiié, Yurika Ishitani, Yoshiyuki Nagai, Yukiko Takaki, Yoshihiro Toyofuku, Takashi Ishii, Shun’ichi |
author_sort |
Ujiié, Yurika |
title |
Unique evolution of foraminiferal calcification to survive global changes |
title_short |
Unique evolution of foraminiferal calcification to survive global changes |
title_full |
Unique evolution of foraminiferal calcification to survive global changes |
title_fullStr |
Unique evolution of foraminiferal calcification to survive global changes |
title_full_unstemmed |
Unique evolution of foraminiferal calcification to survive global changes |
title_sort |
unique evolution of foraminiferal calcification to survive global changes |
publisher |
American Association for the Advancement of Science |
publishDate |
2023 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284544/ https://doi.org/10.1126/sciadv.add3584 |
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Ocean acidification |
genre_facet |
Ocean acidification |
op_source |
Sci Adv |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284544/ http://dx.doi.org/10.1126/sciadv.add3584 |
op_rights |
Copyright © 2023 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY). https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
op_doi |
https://doi.org/10.1126/sciadv.add3584 |
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Science Advances |
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9 |
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25 |
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