DNA methylation differences in noncoding regions in ER negative breast tumors between Black and White women

• Published in: Frontiers in Oncology
• Main Authors: Chen, Jianhong, Higgins, Michael J., Hu, Qiang, Khoury, Thaer, Liu, Song, Ambrosone, Christine B., Gong, Zhihong
• Format: Text
• Language: English
• Published: Frontiers Media S.A. 2023
• Subjects: Oncology; Rho; DML
• Online Access: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244512/; https://doi.org/10.3389/fonc.2023.1167815

INTRODUCTION: Incidence of estrogen receptor (ER)-negative breast cancer, an aggressive tumor subtype associated with worse prognosis, is higher among African American/Black women than other US racial and ethnic groups. The reasons for this disparity remain poorly understood but may be partially exp...