A core of functional complementary bacteria infects oysters in Pacific Oyster Mortality Syndrome
BACKGROUND: The Pacific oyster Crassostrea gigas is one of the main cultivated invertebrate species worldwide. Since 2008, oyster juveniles have been confronted with a lethal syndrome known as the Pacific Oyster Mortality Syndrome (POMS). POMS is a polymicrobial disease initiated by a primary infect...
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ftpubmed:oai:pubmedcentral.nih.gov:10155333 2023-06-11T04:11:09+02:00 A core of functional complementary bacteria infects oysters in Pacific Oyster Mortality Syndrome Clerissi, Camille Luo, Xing Lucasson, Aude Mortaza, Shogofa de Lorgeril, Julien Toulza, Eve Petton, Bruno Escoubas, Jean-Michel Dégremont, Lionel Gueguen, Yannick Destoumieux-Garzόn, Delphine Jacq, Annick Mitta, Guillaume 2023-05-03 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155333/ https://doi.org/10.1186/s42523-023-00246-8 en eng BioMed Central http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155333/ http://dx.doi.org/10.1186/s42523-023-00246-8 © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . Anim Microbiome Research Text 2023 ftpubmed https://doi.org/10.1186/s42523-023-00246-8 2023-05-07T01:23:53Z BACKGROUND: The Pacific oyster Crassostrea gigas is one of the main cultivated invertebrate species worldwide. Since 2008, oyster juveniles have been confronted with a lethal syndrome known as the Pacific Oyster Mortality Syndrome (POMS). POMS is a polymicrobial disease initiated by a primary infection with the herpesvirus OsHV-1 µVar that creates an oyster immunocompromised state and evolves towards a secondary fatal bacteremia. RESULTS: In the present article, we describe the implementation of an unprecedented combination of metabarcoding and metatranscriptomic approaches to show that the sequence of events in POMS pathogenesis is conserved across infectious environments. We also identified a core bacterial consortium which, together with OsHV-1 µVar, forms the POMS pathobiota. This bacterial consortium is characterized by high transcriptional activities and complementary metabolic functions to exploit host’s resources. A significant metabolic specificity was highlighted at the bacterial genus level, suggesting low competition for nutrients between members of the core bacteria. CONCLUSIONS: Lack of metabolic competition between the core bacteria might favor complementary colonization of host tissues and contribute to the conservation of the POMS pathobiota across distinct infectious environments. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s42523-023-00246-8. Text Crassostrea gigas Pacific oyster PubMed Central (PMC) Pacific Animal Microbiome 5 1 |
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Research |
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Research Clerissi, Camille Luo, Xing Lucasson, Aude Mortaza, Shogofa de Lorgeril, Julien Toulza, Eve Petton, Bruno Escoubas, Jean-Michel Dégremont, Lionel Gueguen, Yannick Destoumieux-Garzόn, Delphine Jacq, Annick Mitta, Guillaume A core of functional complementary bacteria infects oysters in Pacific Oyster Mortality Syndrome |
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Research |
description |
BACKGROUND: The Pacific oyster Crassostrea gigas is one of the main cultivated invertebrate species worldwide. Since 2008, oyster juveniles have been confronted with a lethal syndrome known as the Pacific Oyster Mortality Syndrome (POMS). POMS is a polymicrobial disease initiated by a primary infection with the herpesvirus OsHV-1 µVar that creates an oyster immunocompromised state and evolves towards a secondary fatal bacteremia. RESULTS: In the present article, we describe the implementation of an unprecedented combination of metabarcoding and metatranscriptomic approaches to show that the sequence of events in POMS pathogenesis is conserved across infectious environments. We also identified a core bacterial consortium which, together with OsHV-1 µVar, forms the POMS pathobiota. This bacterial consortium is characterized by high transcriptional activities and complementary metabolic functions to exploit host’s resources. A significant metabolic specificity was highlighted at the bacterial genus level, suggesting low competition for nutrients between members of the core bacteria. CONCLUSIONS: Lack of metabolic competition between the core bacteria might favor complementary colonization of host tissues and contribute to the conservation of the POMS pathobiota across distinct infectious environments. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s42523-023-00246-8. |
format |
Text |
author |
Clerissi, Camille Luo, Xing Lucasson, Aude Mortaza, Shogofa de Lorgeril, Julien Toulza, Eve Petton, Bruno Escoubas, Jean-Michel Dégremont, Lionel Gueguen, Yannick Destoumieux-Garzόn, Delphine Jacq, Annick Mitta, Guillaume |
author_facet |
Clerissi, Camille Luo, Xing Lucasson, Aude Mortaza, Shogofa de Lorgeril, Julien Toulza, Eve Petton, Bruno Escoubas, Jean-Michel Dégremont, Lionel Gueguen, Yannick Destoumieux-Garzόn, Delphine Jacq, Annick Mitta, Guillaume |
author_sort |
Clerissi, Camille |
title |
A core of functional complementary bacteria infects oysters in Pacific Oyster Mortality Syndrome |
title_short |
A core of functional complementary bacteria infects oysters in Pacific Oyster Mortality Syndrome |
title_full |
A core of functional complementary bacteria infects oysters in Pacific Oyster Mortality Syndrome |
title_fullStr |
A core of functional complementary bacteria infects oysters in Pacific Oyster Mortality Syndrome |
title_full_unstemmed |
A core of functional complementary bacteria infects oysters in Pacific Oyster Mortality Syndrome |
title_sort |
core of functional complementary bacteria infects oysters in pacific oyster mortality syndrome |
publisher |
BioMed Central |
publishDate |
2023 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155333/ https://doi.org/10.1186/s42523-023-00246-8 |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
Crassostrea gigas Pacific oyster |
genre_facet |
Crassostrea gigas Pacific oyster |
op_source |
Anim Microbiome |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155333/ http://dx.doi.org/10.1186/s42523-023-00246-8 |
op_rights |
© The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
op_doi |
https://doi.org/10.1186/s42523-023-00246-8 |
container_title |
Animal Microbiome |
container_volume |
5 |
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1 |
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1768386031325806592 |