Patient-reported outcome measures for paediatric acute lower respiratory infection studies
BACKGROUND: Patient-reported outcome measures (PROMs) are recommended for capturing meaningful outcomes in clinical trials. The use of PROMs for children with acute lower respiratory infections (ALRIs) has not been systematically reported. We aimed to identify and characterise patient-reported outco...
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ftpubmed:oai:pubmedcentral.nih.gov:10032589 2023-05-15T16:16:40+02:00 Patient-reported outcome measures for paediatric acute lower respiratory infection studies Oakes, Daniel B. Baker, Megan J. McLeod, Charlie Nattabi, Barbara Blyth, Christopher C. 2023-03-08 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032589/ http://www.ncbi.nlm.nih.gov/pubmed/36889787 https://doi.org/10.1183/16000617.0229-2022 en eng European Respiratory Society http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032589/ http://www.ncbi.nlm.nih.gov/pubmed/36889787 http://dx.doi.org/10.1183/16000617.0229-2022 Copyright ©The authors 2023 https://creativecommons.org/licenses/by-nc/4.0/This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org (mailto:permissions@ersnet.org) Eur Respir Rev Reviews Text 2023 ftpubmed https://doi.org/10.1183/16000617.0229-2022 2023-03-26T02:15:55Z BACKGROUND: Patient-reported outcome measures (PROMs) are recommended for capturing meaningful outcomes in clinical trials. The use of PROMs for children with acute lower respiratory infections (ALRIs) has not been systematically reported. We aimed to identify and characterise patient-reported outcomes and PROMs used in paediatric ALRI studies and summarise their measurement properties. METHODS: Medline, Embase and Cochrane were searched (until April 2022). Studies that reported on patient-reported outcome (or measure) use or development and included subjects aged <18 years with ALRIs were included. Study, population and patient-reported outcome (or measure) characteristics were extracted. RESULTS: Of 2793 articles identified, 18 met inclusion criteria, including 12 PROMs. Two disease-specific PROMs were used in settings in which they had been validated. The Canadian Acute Respiratory Illness and Flu Scale was the most frequently used disease-specific PROM (five studies). The EuroQol-Five Dimensions-Youth system was the most frequently used generic PROM (two studies). There was considerable heterogeneity in validation methods. The outcome measures identified in this review lack validation for young children and none involve sufficient content validity for use with First Nations children. CONCLUSIONS: There is an urgent need for PROM development that considers the populations in which the burden of ALRI predominates. Text First Nations PubMed Central (PMC) European Respiratory Review 32 167 220229 |
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Reviews Oakes, Daniel B. Baker, Megan J. McLeod, Charlie Nattabi, Barbara Blyth, Christopher C. Patient-reported outcome measures for paediatric acute lower respiratory infection studies |
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Reviews |
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BACKGROUND: Patient-reported outcome measures (PROMs) are recommended for capturing meaningful outcomes in clinical trials. The use of PROMs for children with acute lower respiratory infections (ALRIs) has not been systematically reported. We aimed to identify and characterise patient-reported outcomes and PROMs used in paediatric ALRI studies and summarise their measurement properties. METHODS: Medline, Embase and Cochrane were searched (until April 2022). Studies that reported on patient-reported outcome (or measure) use or development and included subjects aged <18 years with ALRIs were included. Study, population and patient-reported outcome (or measure) characteristics were extracted. RESULTS: Of 2793 articles identified, 18 met inclusion criteria, including 12 PROMs. Two disease-specific PROMs were used in settings in which they had been validated. The Canadian Acute Respiratory Illness and Flu Scale was the most frequently used disease-specific PROM (five studies). The EuroQol-Five Dimensions-Youth system was the most frequently used generic PROM (two studies). There was considerable heterogeneity in validation methods. The outcome measures identified in this review lack validation for young children and none involve sufficient content validity for use with First Nations children. CONCLUSIONS: There is an urgent need for PROM development that considers the populations in which the burden of ALRI predominates. |
format |
Text |
author |
Oakes, Daniel B. Baker, Megan J. McLeod, Charlie Nattabi, Barbara Blyth, Christopher C. |
author_facet |
Oakes, Daniel B. Baker, Megan J. McLeod, Charlie Nattabi, Barbara Blyth, Christopher C. |
author_sort |
Oakes, Daniel B. |
title |
Patient-reported outcome measures for paediatric acute lower respiratory infection studies |
title_short |
Patient-reported outcome measures for paediatric acute lower respiratory infection studies |
title_full |
Patient-reported outcome measures for paediatric acute lower respiratory infection studies |
title_fullStr |
Patient-reported outcome measures for paediatric acute lower respiratory infection studies |
title_full_unstemmed |
Patient-reported outcome measures for paediatric acute lower respiratory infection studies |
title_sort |
patient-reported outcome measures for paediatric acute lower respiratory infection studies |
publisher |
European Respiratory Society |
publishDate |
2023 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032589/ http://www.ncbi.nlm.nih.gov/pubmed/36889787 https://doi.org/10.1183/16000617.0229-2022 |
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First Nations |
genre_facet |
First Nations |
op_source |
Eur Respir Rev |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032589/ http://www.ncbi.nlm.nih.gov/pubmed/36889787 http://dx.doi.org/10.1183/16000617.0229-2022 |
op_rights |
Copyright ©The authors 2023 https://creativecommons.org/licenses/by-nc/4.0/This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org (mailto:permissions@ersnet.org) |
op_doi |
https://doi.org/10.1183/16000617.0229-2022 |
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European Respiratory Review |
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32 |
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167 |
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220229 |
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1766002524991520768 |