Frost fighters: unveiling the potential of microbial antifreeze proteins in biotech innovation.
Polar environments pose extreme challenges for life due to low temperatures, limited water, high radiation, and frozen landscapes. Despite these harsh conditions, numerous macro and microorganisms have developed adaptive strategies to reduce the detrimental effects of extreme cold. A primary surviva...
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Online Access: | https://doi.org/10.1093/jambio/lxae140 https://pubmed.ncbi.nlm.nih.gov/38877650 |
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ftpubmed:38877650 2024-09-15T17:43:59+00:00 Frost fighters: unveiling the potential of microbial antifreeze proteins in biotech innovation. Lopes, Joana Camila Kinasz, Camila Tomazini Luiz, Alanna Maylle Cararo Kreusch, Marianne Gabi Duarte, Rubens Tadeu Delgado 2024 Jun 03 https://doi.org/10.1093/jambio/lxae140 https://pubmed.ncbi.nlm.nih.gov/38877650 eng eng Silverchair Information Systems https://doi.org/10.1093/jambio/lxae140 https://pubmed.ncbi.nlm.nih.gov/38877650 © The Author(s) 2024. Published by Oxford University Press on behalf of Applied Microbiology International. J Appl Microbiol ISSN:1365-2672 Volume:135 Issue:6 Antarctica Arctic antifreeze proteins cryoprotection psychrophile Journal Article Review 2024 ftpubmed https://doi.org/10.1093/jambio/lxae140 2024-06-28T16:02:00Z Polar environments pose extreme challenges for life due to low temperatures, limited water, high radiation, and frozen landscapes. Despite these harsh conditions, numerous macro and microorganisms have developed adaptive strategies to reduce the detrimental effects of extreme cold. A primary survival tactic involves avoiding or tolerating intra and extracellular freezing. Many organisms achieve this by maintaining a supercooled state by producing small organic compounds like sugars, glycerol, and amino acids, or through increasing solute concentration. Another approach is the synthesis of ice-binding proteins, specifically antifreeze proteins (AFPs), which hinder ice crystal growth below the melting point. This adaptation is crucial for preventing intracellular ice formation, which could be lethal, and ensuring the presence of liquid water around cells. AFPs have independently evolved in different species, exhibiting distinct thermal hysteresis and ice structuring properties. Beyond their ecological role, AFPs have garnered significant attention in biotechnology for potential applications in the food, agriculture, and pharmaceutical industries. This review aims to offer a thorough insight into the activity and impacts of AFPs on water, examining their significance in cold-adapted organisms, and exploring the diversity of microbial AFPs. Using a meta-analysis from cultivation-based and cultivation-independent data, we evaluate the correlation between AFP-producing microorganisms and cold environments. We also explore small and large-scale biotechnological applications of AFPs, providing a perspective for future research. Review Antarc* Antarctica PubMed Central (PMC) Journal of Applied Microbiology 135 6 |
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Open Polar |
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PubMed Central (PMC) |
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ftpubmed |
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English |
topic |
Antarctica Arctic antifreeze proteins cryoprotection psychrophile |
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Antarctica Arctic antifreeze proteins cryoprotection psychrophile Lopes, Joana Camila Kinasz, Camila Tomazini Luiz, Alanna Maylle Cararo Kreusch, Marianne Gabi Duarte, Rubens Tadeu Delgado Frost fighters: unveiling the potential of microbial antifreeze proteins in biotech innovation. |
topic_facet |
Antarctica Arctic antifreeze proteins cryoprotection psychrophile |
description |
Polar environments pose extreme challenges for life due to low temperatures, limited water, high radiation, and frozen landscapes. Despite these harsh conditions, numerous macro and microorganisms have developed adaptive strategies to reduce the detrimental effects of extreme cold. A primary survival tactic involves avoiding or tolerating intra and extracellular freezing. Many organisms achieve this by maintaining a supercooled state by producing small organic compounds like sugars, glycerol, and amino acids, or through increasing solute concentration. Another approach is the synthesis of ice-binding proteins, specifically antifreeze proteins (AFPs), which hinder ice crystal growth below the melting point. This adaptation is crucial for preventing intracellular ice formation, which could be lethal, and ensuring the presence of liquid water around cells. AFPs have independently evolved in different species, exhibiting distinct thermal hysteresis and ice structuring properties. Beyond their ecological role, AFPs have garnered significant attention in biotechnology for potential applications in the food, agriculture, and pharmaceutical industries. This review aims to offer a thorough insight into the activity and impacts of AFPs on water, examining their significance in cold-adapted organisms, and exploring the diversity of microbial AFPs. Using a meta-analysis from cultivation-based and cultivation-independent data, we evaluate the correlation between AFP-producing microorganisms and cold environments. We also explore small and large-scale biotechnological applications of AFPs, providing a perspective for future research. |
format |
Review |
author |
Lopes, Joana Camila Kinasz, Camila Tomazini Luiz, Alanna Maylle Cararo Kreusch, Marianne Gabi Duarte, Rubens Tadeu Delgado |
author_facet |
Lopes, Joana Camila Kinasz, Camila Tomazini Luiz, Alanna Maylle Cararo Kreusch, Marianne Gabi Duarte, Rubens Tadeu Delgado |
author_sort |
Lopes, Joana Camila |
title |
Frost fighters: unveiling the potential of microbial antifreeze proteins in biotech innovation. |
title_short |
Frost fighters: unveiling the potential of microbial antifreeze proteins in biotech innovation. |
title_full |
Frost fighters: unveiling the potential of microbial antifreeze proteins in biotech innovation. |
title_fullStr |
Frost fighters: unveiling the potential of microbial antifreeze proteins in biotech innovation. |
title_full_unstemmed |
Frost fighters: unveiling the potential of microbial antifreeze proteins in biotech innovation. |
title_sort |
frost fighters: unveiling the potential of microbial antifreeze proteins in biotech innovation. |
publisher |
Silverchair Information Systems |
publishDate |
2024 |
url |
https://doi.org/10.1093/jambio/lxae140 https://pubmed.ncbi.nlm.nih.gov/38877650 |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_source |
J Appl Microbiol ISSN:1365-2672 Volume:135 Issue:6 |
op_relation |
https://doi.org/10.1093/jambio/lxae140 https://pubmed.ncbi.nlm.nih.gov/38877650 |
op_rights |
© The Author(s) 2024. Published by Oxford University Press on behalf of Applied Microbiology International. |
op_doi |
https://doi.org/10.1093/jambio/lxae140 |
container_title |
Journal of Applied Microbiology |
container_volume |
135 |
container_issue |
6 |
_version_ |
1810491257203458048 |