Diversity of major histocompatibility complex of II B gene and mate choice in a monogamous and long-lived seabird, the Little Auk (Alle alle).
The major histocompatibility complex (MHC) plays a key role in the adaptive immune system of vertebrates, and is known to influence mate choice in many species. In birds, the MHC has been extensively examined but mainly in galliforms and passerines while other taxa that represent specific ecological...
Published in: | PLOS ONE |
---|---|
Main Authors: | , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Public Library of Science
2024
|
Subjects: | |
Online Access: | https://doi.org/10.1371/journal.pone.0304275 https://pubmed.ncbi.nlm.nih.gov/38865310 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11168636/ |
id |
ftpubmed:38865310 |
---|---|
record_format |
openpolar |
spelling |
ftpubmed:38865310 2024-09-15T17:36:50+00:00 Diversity of major histocompatibility complex of II B gene and mate choice in a monogamous and long-lived seabird, the Little Auk (Alle alle). Wojczulanis-Jakubas, Katarzyna Hoover, Brian Jakubas, Dariusz Fort, Jérôme Grémillet, David Gavrilo, Maria Zielińska, Sylwia Zagalska-Neubauer, Magdalena 2024 https://doi.org/10.1371/journal.pone.0304275 https://pubmed.ncbi.nlm.nih.gov/38865310 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11168636/ eng eng Public Library of Science https://doi.org/10.1371/journal.pone.0304275 https://pubmed.ncbi.nlm.nih.gov/38865310 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11168636/ Copyright: © 2024 Wojczulanis-Jakubas et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. PLoS One ISSN:1932-6203 Volume:19 Issue:6 Journal Article 2024 ftpubmed https://doi.org/10.1371/journal.pone.0304275 2024-06-25T16:01:00Z The major histocompatibility complex (MHC) plays a key role in the adaptive immune system of vertebrates, and is known to influence mate choice in many species. In birds, the MHC has been extensively examined but mainly in galliforms and passerines while other taxa that represent specific ecological and evolutionary life-histories, like seabirds, are underexamined. Here, we characterized diversity of MHC Class II B exon 2 in a colonial pelagic seabird, the Little Auk (or Dovekie Alle alle). We further examined whether MHC variation could be maintained through balancing selection and disassortative mating. We found high polymorphism at the genotyped MHC fragment, characterizing 99 distinct alleles across 140 individuals from three populations. The alleles frequencies exhibited a similar skewed distribution in both sexes, with the four most commonly occurring alleles representing approximately 35% of allelic variation. The results of a Bayesian site-by-site selection analysis suggest evidence of balancing selection and no direct evidence for MHC-dependent disassortative mating preferences in the Little Auk. The latter result might be attributed to the high overall polymorphism of the examined fragment, which itself may be maintained by the large population size of the species. Article in Journal/Newspaper Alle alle Dovekie little auk PubMed Central (PMC) PLOS ONE 19 6 e0304275 |
institution |
Open Polar |
collection |
PubMed Central (PMC) |
op_collection_id |
ftpubmed |
language |
English |
description |
The major histocompatibility complex (MHC) plays a key role in the adaptive immune system of vertebrates, and is known to influence mate choice in many species. In birds, the MHC has been extensively examined but mainly in galliforms and passerines while other taxa that represent specific ecological and evolutionary life-histories, like seabirds, are underexamined. Here, we characterized diversity of MHC Class II B exon 2 in a colonial pelagic seabird, the Little Auk (or Dovekie Alle alle). We further examined whether MHC variation could be maintained through balancing selection and disassortative mating. We found high polymorphism at the genotyped MHC fragment, characterizing 99 distinct alleles across 140 individuals from three populations. The alleles frequencies exhibited a similar skewed distribution in both sexes, with the four most commonly occurring alleles representing approximately 35% of allelic variation. The results of a Bayesian site-by-site selection analysis suggest evidence of balancing selection and no direct evidence for MHC-dependent disassortative mating preferences in the Little Auk. The latter result might be attributed to the high overall polymorphism of the examined fragment, which itself may be maintained by the large population size of the species. |
format |
Article in Journal/Newspaper |
author |
Wojczulanis-Jakubas, Katarzyna Hoover, Brian Jakubas, Dariusz Fort, Jérôme Grémillet, David Gavrilo, Maria Zielińska, Sylwia Zagalska-Neubauer, Magdalena |
spellingShingle |
Wojczulanis-Jakubas, Katarzyna Hoover, Brian Jakubas, Dariusz Fort, Jérôme Grémillet, David Gavrilo, Maria Zielińska, Sylwia Zagalska-Neubauer, Magdalena Diversity of major histocompatibility complex of II B gene and mate choice in a monogamous and long-lived seabird, the Little Auk (Alle alle). |
author_facet |
Wojczulanis-Jakubas, Katarzyna Hoover, Brian Jakubas, Dariusz Fort, Jérôme Grémillet, David Gavrilo, Maria Zielińska, Sylwia Zagalska-Neubauer, Magdalena |
author_sort |
Wojczulanis-Jakubas, Katarzyna |
title |
Diversity of major histocompatibility complex of II B gene and mate choice in a monogamous and long-lived seabird, the Little Auk (Alle alle). |
title_short |
Diversity of major histocompatibility complex of II B gene and mate choice in a monogamous and long-lived seabird, the Little Auk (Alle alle). |
title_full |
Diversity of major histocompatibility complex of II B gene and mate choice in a monogamous and long-lived seabird, the Little Auk (Alle alle). |
title_fullStr |
Diversity of major histocompatibility complex of II B gene and mate choice in a monogamous and long-lived seabird, the Little Auk (Alle alle). |
title_full_unstemmed |
Diversity of major histocompatibility complex of II B gene and mate choice in a monogamous and long-lived seabird, the Little Auk (Alle alle). |
title_sort |
diversity of major histocompatibility complex of ii b gene and mate choice in a monogamous and long-lived seabird, the little auk (alle alle). |
publisher |
Public Library of Science |
publishDate |
2024 |
url |
https://doi.org/10.1371/journal.pone.0304275 https://pubmed.ncbi.nlm.nih.gov/38865310 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11168636/ |
genre |
Alle alle Dovekie little auk |
genre_facet |
Alle alle Dovekie little auk |
op_source |
PLoS One ISSN:1932-6203 Volume:19 Issue:6 |
op_relation |
https://doi.org/10.1371/journal.pone.0304275 https://pubmed.ncbi.nlm.nih.gov/38865310 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11168636/ |
op_rights |
Copyright: © 2024 Wojczulanis-Jakubas et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
op_doi |
https://doi.org/10.1371/journal.pone.0304275 |
container_title |
PLOS ONE |
container_volume |
19 |
container_issue |
6 |
container_start_page |
e0304275 |
_version_ |
1810492510035771392 |