Analysis of admixed Greenlandic siblings shows that the mean genotypic values for metabolic phenotypes differ between Inuit and Europeans.

Disease prevalence and mean phenotype values differ between many populations, including Inuit and Europeans. Whether these differences are partly explained by genetic differences or solely due to differences in environmental exposures is still unknown, because estimates of the genetic contribution t...

Full description

Bibliographic Details
Published in:Genome Medicine
Main Authors: Lin, Long, Andersen, Mette K, Stæger, Frederik Filip, Li, Zilong, Hanghøj, Kristian, Linneberg, Allan, Grarup, Niels, Jørgensen, Marit Eika, Hansen, Torben, Moltke, Ida, Albrechtsen, Anders
Format: Article in Journal/Newspaper
Language:English
Published: BioMed Central 2024
Subjects:
Admixture
Genotypic value
Greenlandic population
Sibling analysis
greenlandic
inuit
Online Access:https://doi.org/10.1186/s13073-024-01326-3
https://pubmed.ncbi.nlm.nih.gov/38778393
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11112775/
id ftpubmed:38778393
record_format openpolar
spelling ftpubmed:38778393 2024-09-15T18:10:15+00:00 Analysis of admixed Greenlandic siblings shows that the mean genotypic values for metabolic phenotypes differ between Inuit and Europeans. Lin, Long Andersen, Mette K Stæger, Frederik Filip Li, Zilong Hanghøj, Kristian Linneberg, Allan Grarup, Niels Jørgensen, Marit Eika Hansen, Torben Moltke, Ida Albrechtsen, Anders 2024-05-23 https://doi.org/10.1186/s13073-024-01326-3 https://pubmed.ncbi.nlm.nih.gov/38778393 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11112775/ eng eng BioMed Central https://doi.org/10.1186/s13073-024-01326-3 https://pubmed.ncbi.nlm.nih.gov/38778393 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11112775/ © 2024. The Author(s). Genome Med ISSN:1756-994X Volume:16 Issue:1 Admixture Genotypic value Greenlandic population Sibling analysis Journal Article Research Support, Non-U.S. Gov't 2024 ftpubmed https://doi.org/10.1186/s13073-024-01326-3 2024-07-08T16:01:00Z Disease prevalence and mean phenotype values differ between many populations, including Inuit and Europeans. Whether these differences are partly explained by genetic differences or solely due to differences in environmental exposures is still unknown, because estimates of the genetic contribution to these means, which we will here refer to as mean genotypic values, are easily confounded, and because studies across genetically diverse populations are lacking. Article in Journal/Newspaper greenlandic inuit PubMed Central (PMC) Genome Medicine 16 1
institution Open Polar
collection PubMed Central (PMC)
op_collection_id ftpubmed
language English
topic Admixture
Genotypic value
Greenlandic population
Sibling analysis
spellingShingle Admixture
Genotypic value
Greenlandic population
Sibling analysis
Lin, Long
Andersen, Mette K
Stæger, Frederik Filip
Li, Zilong
Hanghøj, Kristian
Linneberg, Allan
Grarup, Niels
Jørgensen, Marit Eika
Hansen, Torben
Moltke, Ida
Albrechtsen, Anders
Analysis of admixed Greenlandic siblings shows that the mean genotypic values for metabolic phenotypes differ between Inuit and Europeans.
topic_facet Admixture
Genotypic value
Greenlandic population
Sibling analysis
description Disease prevalence and mean phenotype values differ between many populations, including Inuit and Europeans. Whether these differences are partly explained by genetic differences or solely due to differences in environmental exposures is still unknown, because estimates of the genetic contribution to these means, which we will here refer to as mean genotypic values, are easily confounded, and because studies across genetically diverse populations are lacking.
format Article in Journal/Newspaper
author Lin, Long
Andersen, Mette K
Stæger, Frederik Filip
Li, Zilong
Hanghøj, Kristian
Linneberg, Allan
Grarup, Niels
Jørgensen, Marit Eika
Hansen, Torben
Moltke, Ida
Albrechtsen, Anders
author_facet Lin, Long
Andersen, Mette K
Stæger, Frederik Filip
Li, Zilong
Hanghøj, Kristian
Linneberg, Allan
Grarup, Niels
Jørgensen, Marit Eika
Hansen, Torben
Moltke, Ida
Albrechtsen, Anders
author_sort Lin, Long
title Analysis of admixed Greenlandic siblings shows that the mean genotypic values for metabolic phenotypes differ between Inuit and Europeans.
title_short Analysis of admixed Greenlandic siblings shows that the mean genotypic values for metabolic phenotypes differ between Inuit and Europeans.
title_full Analysis of admixed Greenlandic siblings shows that the mean genotypic values for metabolic phenotypes differ between Inuit and Europeans.
title_fullStr Analysis of admixed Greenlandic siblings shows that the mean genotypic values for metabolic phenotypes differ between Inuit and Europeans.
title_full_unstemmed Analysis of admixed Greenlandic siblings shows that the mean genotypic values for metabolic phenotypes differ between Inuit and Europeans.
title_sort analysis of admixed greenlandic siblings shows that the mean genotypic values for metabolic phenotypes differ between inuit and europeans.
publisher BioMed Central
publishDate 2024
url https://doi.org/10.1186/s13073-024-01326-3
https://pubmed.ncbi.nlm.nih.gov/38778393
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11112775/
genre greenlandic
inuit
genre_facet greenlandic
inuit
op_source Genome Med
ISSN:1756-994X
Volume:16
Issue:1
op_relation https://doi.org/10.1186/s13073-024-01326-3
https://pubmed.ncbi.nlm.nih.gov/38778393
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11112775/
op_rights © 2024. The Author(s).
op_doi https://doi.org/10.1186/s13073-024-01326-3
container_title Genome Medicine
container_volume 16
container_issue 1
_version_ 1810447848276230144

Similar Items