Use of the Phylobone database for the annotation of bone extracellular matrix proteins in reindeer (
Bone extracellular matrix (ECM) proteins play a key role in bone formation and regeneration, including structural and regulatory functions. The Phylobone database consists of 255 ECM protein groups from 39 species and can be used to support bone research. Here, we gathered bone ECM proteins from rei...
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ftpubmed:38614461 2024-05-12T08:10:18+00:00 Use of the Phylobone database for the annotation of bone extracellular matrix proteins in reindeer ( Sánchez-Reverté, Alba Fontcuberta-Rigo, Margalida Nakamura, Miho Puigbò, Pere 2024 Apr-Jun https://doi.org/10.1177/00368504241244666 https://pubmed.ncbi.nlm.nih.gov/38614461 eng eng Atypon https://doi.org/10.1177/00368504241244666 https://pubmed.ncbi.nlm.nih.gov/38614461 Sci Prog ISSN:2047-7163 Volume:107 Issue:2 Extracellular matrix Rangifer tarandus bone cervidae database proteins Journal Article 2024 ftpubmed https://doi.org/10.1177/00368504241244666 2024-04-14T16:01:00Z Bone extracellular matrix (ECM) proteins play a key role in bone formation and regeneration, including structural and regulatory functions. The Phylobone database consists of 255 ECM protein groups from 39 species and can be used to support bone research. Here, we gathered bone ECM proteins from reindeer (Rangifer tarandus), a member of the Cervidae family. The importance of reindeer lies in their ability to regenerate their antlers, in both male and female individuals. Protein sequences were extracted from the National Center for Biotechnology Information's repository and selected by homology searches. We identified 215 proteins and their corresponding functional domains, which are putatively present in the bone ECM of reindeer. Protein sequence alignments have shown a high degree of conservation between R. tarandus and other members of the Cervidae family. This update expands the Phylobone database and shows that it is a useful resource for the preliminary annotation of bone ECM proteins in novel proteomes. Article in Journal/Newspaper Rangifer tarandus PubMed Central (PMC) Science Progress 107 2 |
institution |
Open Polar |
collection |
PubMed Central (PMC) |
op_collection_id |
ftpubmed |
language |
English |
topic |
Extracellular matrix Rangifer tarandus bone cervidae database proteins |
spellingShingle |
Extracellular matrix Rangifer tarandus bone cervidae database proteins Sánchez-Reverté, Alba Fontcuberta-Rigo, Margalida Nakamura, Miho Puigbò, Pere Use of the Phylobone database for the annotation of bone extracellular matrix proteins in reindeer ( |
topic_facet |
Extracellular matrix Rangifer tarandus bone cervidae database proteins |
description |
Bone extracellular matrix (ECM) proteins play a key role in bone formation and regeneration, including structural and regulatory functions. The Phylobone database consists of 255 ECM protein groups from 39 species and can be used to support bone research. Here, we gathered bone ECM proteins from reindeer (Rangifer tarandus), a member of the Cervidae family. The importance of reindeer lies in their ability to regenerate their antlers, in both male and female individuals. Protein sequences were extracted from the National Center for Biotechnology Information's repository and selected by homology searches. We identified 215 proteins and their corresponding functional domains, which are putatively present in the bone ECM of reindeer. Protein sequence alignments have shown a high degree of conservation between R. tarandus and other members of the Cervidae family. This update expands the Phylobone database and shows that it is a useful resource for the preliminary annotation of bone ECM proteins in novel proteomes. |
format |
Article in Journal/Newspaper |
author |
Sánchez-Reverté, Alba Fontcuberta-Rigo, Margalida Nakamura, Miho Puigbò, Pere |
author_facet |
Sánchez-Reverté, Alba Fontcuberta-Rigo, Margalida Nakamura, Miho Puigbò, Pere |
author_sort |
Sánchez-Reverté, Alba |
title |
Use of the Phylobone database for the annotation of bone extracellular matrix proteins in reindeer ( |
title_short |
Use of the Phylobone database for the annotation of bone extracellular matrix proteins in reindeer ( |
title_full |
Use of the Phylobone database for the annotation of bone extracellular matrix proteins in reindeer ( |
title_fullStr |
Use of the Phylobone database for the annotation of bone extracellular matrix proteins in reindeer ( |
title_full_unstemmed |
Use of the Phylobone database for the annotation of bone extracellular matrix proteins in reindeer ( |
title_sort |
use of the phylobone database for the annotation of bone extracellular matrix proteins in reindeer ( |
publisher |
Atypon |
publishDate |
2024 |
url |
https://doi.org/10.1177/00368504241244666 https://pubmed.ncbi.nlm.nih.gov/38614461 |
genre |
Rangifer tarandus |
genre_facet |
Rangifer tarandus |
op_source |
Sci Prog ISSN:2047-7163 Volume:107 Issue:2 |
op_relation |
https://doi.org/10.1177/00368504241244666 https://pubmed.ncbi.nlm.nih.gov/38614461 |
op_doi |
https://doi.org/10.1177/00368504241244666 |
container_title |
Science Progress |
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107 |
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2 |
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1798853735590395904 |