The cost of research: Lasting effects of capture, surgery and muscle biopsy on brown bear (
Animal models are a key component of translational medicine, helping transfer scientific findings into practical applications for human health. A fundamental principle of research ethics involves weighing the benefits of the research to society against the burden imposed on the animals used for scie...
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Language: | English |
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Online Access: | https://doi.org/10.1017/awf.2023.95 https://pubmed.ncbi.nlm.nih.gov/38510989 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10951663/ |
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ftpubmed:38510989 2024-06-23T07:57:22+00:00 The cost of research: Lasting effects of capture, surgery and muscle biopsy on brown bear ( Thiel, Alexandra Hertel, Anne G Giroud, Sylvain Friebe, Andrea Fuchs, Boris Kindberg, Jonas Græsli, Anne Randi Arnemo, Jon M Evans, Alina L 2023 https://doi.org/10.1017/awf.2023.95 https://pubmed.ncbi.nlm.nih.gov/38510989 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10951663/ eng eng PubMed Central https://doi.org/10.1017/awf.2023.95 https://pubmed.ncbi.nlm.nih.gov/38510989 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10951663/ © The Author(s) 2023. Anim Welf ISSN:2054-1538 Volume:32 animal welfare body temperature capture effects ecophysiology hibernation movement Journal Article 2023 ftpubmed https://doi.org/10.1017/awf.2023.95 2024-06-13T16:02:00Z Animal models are a key component of translational medicine, helping transfer scientific findings into practical applications for human health. A fundamental principle of research ethics involves weighing the benefits of the research to society against the burden imposed on the animals used for scientific purposes. The utilisation of wild animals for research requires evaluation of the effects of capture and invasive sampling. Determining the severity and duration of these interventions on the animal's physiology and behaviour allows for refining study methodology and for excluding or accounting for biased data. In this study, 39 Scandinavian brown bears (Ursus arctos) captured either while hibernating in winter or via helicopter in summer and that underwent surgery as part of a human health project had their movement, body temperature and timing of onset of hibernation compared with those of 14 control bears that had not been captured during the same period. Bears captured in winter and summer showed decreased movement from den exit until late summer, compared to those in the control group. Bears captured in summer showed reduced movement and body temperature for at least, respectively, 14 and 3 days, with an 11% decrease in hourly distance, compared to pre-capture levels, but did not differ in the timing of hibernation onset. We reveal that brown bear behaviour and physiology can be altered in response to capture and surgery for days to months, post-capture. This has broad implications for the conclusions of wildlife studies that rely upon invasive sampling. Article in Journal/Newspaper Ursus arctos PubMed Central (PMC) Animal Welfare 32 |
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English |
topic |
animal welfare body temperature capture effects ecophysiology hibernation movement |
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animal welfare body temperature capture effects ecophysiology hibernation movement Thiel, Alexandra Hertel, Anne G Giroud, Sylvain Friebe, Andrea Fuchs, Boris Kindberg, Jonas Græsli, Anne Randi Arnemo, Jon M Evans, Alina L The cost of research: Lasting effects of capture, surgery and muscle biopsy on brown bear ( |
topic_facet |
animal welfare body temperature capture effects ecophysiology hibernation movement |
description |
Animal models are a key component of translational medicine, helping transfer scientific findings into practical applications for human health. A fundamental principle of research ethics involves weighing the benefits of the research to society against the burden imposed on the animals used for scientific purposes. The utilisation of wild animals for research requires evaluation of the effects of capture and invasive sampling. Determining the severity and duration of these interventions on the animal's physiology and behaviour allows for refining study methodology and for excluding or accounting for biased data. In this study, 39 Scandinavian brown bears (Ursus arctos) captured either while hibernating in winter or via helicopter in summer and that underwent surgery as part of a human health project had their movement, body temperature and timing of onset of hibernation compared with those of 14 control bears that had not been captured during the same period. Bears captured in winter and summer showed decreased movement from den exit until late summer, compared to those in the control group. Bears captured in summer showed reduced movement and body temperature for at least, respectively, 14 and 3 days, with an 11% decrease in hourly distance, compared to pre-capture levels, but did not differ in the timing of hibernation onset. We reveal that brown bear behaviour and physiology can be altered in response to capture and surgery for days to months, post-capture. This has broad implications for the conclusions of wildlife studies that rely upon invasive sampling. |
format |
Article in Journal/Newspaper |
author |
Thiel, Alexandra Hertel, Anne G Giroud, Sylvain Friebe, Andrea Fuchs, Boris Kindberg, Jonas Græsli, Anne Randi Arnemo, Jon M Evans, Alina L |
author_facet |
Thiel, Alexandra Hertel, Anne G Giroud, Sylvain Friebe, Andrea Fuchs, Boris Kindberg, Jonas Græsli, Anne Randi Arnemo, Jon M Evans, Alina L |
author_sort |
Thiel, Alexandra |
title |
The cost of research: Lasting effects of capture, surgery and muscle biopsy on brown bear ( |
title_short |
The cost of research: Lasting effects of capture, surgery and muscle biopsy on brown bear ( |
title_full |
The cost of research: Lasting effects of capture, surgery and muscle biopsy on brown bear ( |
title_fullStr |
The cost of research: Lasting effects of capture, surgery and muscle biopsy on brown bear ( |
title_full_unstemmed |
The cost of research: Lasting effects of capture, surgery and muscle biopsy on brown bear ( |
title_sort |
cost of research: lasting effects of capture, surgery and muscle biopsy on brown bear ( |
publisher |
PubMed Central |
publishDate |
2023 |
url |
https://doi.org/10.1017/awf.2023.95 https://pubmed.ncbi.nlm.nih.gov/38510989 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10951663/ |
genre |
Ursus arctos |
genre_facet |
Ursus arctos |
op_source |
Anim Welf ISSN:2054-1538 Volume:32 |
op_relation |
https://doi.org/10.1017/awf.2023.95 https://pubmed.ncbi.nlm.nih.gov/38510989 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10951663/ |
op_rights |
© The Author(s) 2023. |
op_doi |
https://doi.org/10.1017/awf.2023.95 |
container_title |
Animal Welfare |
container_volume |
32 |
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1802650973142777856 |