Genomics of post-bottleneck recovery in the northern elephant seal.
Populations and species are threatened by human pressure, but their fate is variable. Some depleted populations, such as that of the northern elephant seal (Mirounga angustirostris), recover rapidly even when the surviving population was small. The northern elephant seal was hunted extensively and t...
Published in: | Nature Ecology & Evolution |
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Online Access: | https://doi.org/10.1038/s41559-024-02337-4 https://pubmed.ncbi.nlm.nih.gov/38383849 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11009102/ |
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ftpubmed:38383849 2024-05-12T08:03:08+00:00 Genomics of post-bottleneck recovery in the northern elephant seal. Hoelzel, A Rus Gkafas, Georgios A Kang, Hui Sarigol, Fatih Le Boeuf, Burney Costa, Daniel P Beltran, Roxanne S Reiter, Joanne Robinson, Patrick W McInerney, Nancy Seim, Inge Sun, Shuai Fan, Guangyi Li, Songhai 2024 Apr https://doi.org/10.1038/s41559-024-02337-4 https://pubmed.ncbi.nlm.nih.gov/38383849 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11009102/ eng eng Nature Publishing Group https://doi.org/10.1038/s41559-024-02337-4 https://pubmed.ncbi.nlm.nih.gov/38383849 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11009102/ © 2024. The Author(s). Nat Ecol Evol ISSN:2397-334X Volume:8 Issue:4 Journal Article 2024 ftpubmed https://doi.org/10.1038/s41559-024-02337-4 2024-04-14T16:01:00Z Populations and species are threatened by human pressure, but their fate is variable. Some depleted populations, such as that of the northern elephant seal (Mirounga angustirostris), recover rapidly even when the surviving population was small. The northern elephant seal was hunted extensively and taken by collectors between the early 1800s and 1892, suffering an extreme population bottleneck as a consequence. Recovery was rapid and now there are over 200,000 individuals. We sequenced 260 modern and 8 historical northern elephant seal nuclear genomes to assess the impact of the population bottleneck on individual northern elephant seals and to better understand their recovery. Here we show that inbreeding, an increase in the frequency of alleles compromised by lost function, and allele frequency distortion, reduced the fitness of breeding males and females, as well as the performance of adult females on foraging migrations. We provide a detailed investigation of the impact of a severe bottleneck on fitness at the genomic level and report on the role of specific gene systems. Article in Journal/Newspaper Elephant Seal Elephant Seals PubMed Central (PMC) Nature Ecology & Evolution 8 4 686 694 |
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Populations and species are threatened by human pressure, but their fate is variable. Some depleted populations, such as that of the northern elephant seal (Mirounga angustirostris), recover rapidly even when the surviving population was small. The northern elephant seal was hunted extensively and taken by collectors between the early 1800s and 1892, suffering an extreme population bottleneck as a consequence. Recovery was rapid and now there are over 200,000 individuals. We sequenced 260 modern and 8 historical northern elephant seal nuclear genomes to assess the impact of the population bottleneck on individual northern elephant seals and to better understand their recovery. Here we show that inbreeding, an increase in the frequency of alleles compromised by lost function, and allele frequency distortion, reduced the fitness of breeding males and females, as well as the performance of adult females on foraging migrations. We provide a detailed investigation of the impact of a severe bottleneck on fitness at the genomic level and report on the role of specific gene systems. |
format |
Article in Journal/Newspaper |
author |
Hoelzel, A Rus Gkafas, Georgios A Kang, Hui Sarigol, Fatih Le Boeuf, Burney Costa, Daniel P Beltran, Roxanne S Reiter, Joanne Robinson, Patrick W McInerney, Nancy Seim, Inge Sun, Shuai Fan, Guangyi Li, Songhai |
spellingShingle |
Hoelzel, A Rus Gkafas, Georgios A Kang, Hui Sarigol, Fatih Le Boeuf, Burney Costa, Daniel P Beltran, Roxanne S Reiter, Joanne Robinson, Patrick W McInerney, Nancy Seim, Inge Sun, Shuai Fan, Guangyi Li, Songhai Genomics of post-bottleneck recovery in the northern elephant seal. |
author_facet |
Hoelzel, A Rus Gkafas, Georgios A Kang, Hui Sarigol, Fatih Le Boeuf, Burney Costa, Daniel P Beltran, Roxanne S Reiter, Joanne Robinson, Patrick W McInerney, Nancy Seim, Inge Sun, Shuai Fan, Guangyi Li, Songhai |
author_sort |
Hoelzel, A Rus |
title |
Genomics of post-bottleneck recovery in the northern elephant seal. |
title_short |
Genomics of post-bottleneck recovery in the northern elephant seal. |
title_full |
Genomics of post-bottleneck recovery in the northern elephant seal. |
title_fullStr |
Genomics of post-bottleneck recovery in the northern elephant seal. |
title_full_unstemmed |
Genomics of post-bottleneck recovery in the northern elephant seal. |
title_sort |
genomics of post-bottleneck recovery in the northern elephant seal. |
publisher |
Nature Publishing Group |
publishDate |
2024 |
url |
https://doi.org/10.1038/s41559-024-02337-4 https://pubmed.ncbi.nlm.nih.gov/38383849 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11009102/ |
genre |
Elephant Seal Elephant Seals |
genre_facet |
Elephant Seal Elephant Seals |
op_source |
Nat Ecol Evol ISSN:2397-334X Volume:8 Issue:4 |
op_relation |
https://doi.org/10.1038/s41559-024-02337-4 https://pubmed.ncbi.nlm.nih.gov/38383849 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11009102/ |
op_rights |
© 2024. The Author(s). |
op_doi |
https://doi.org/10.1038/s41559-024-02337-4 |
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Nature Ecology & Evolution |
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8 |
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4 |
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686 |
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694 |
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1798845235864797184 |