Melatonin secretion in SAD patients and healthy subjects matched with respect to age and sex.
Among the competing hypotheses concerning the aetiology of SAD is the melatonin hypothesis, which is the target of this study. 5 test subjects with SPAQ seasonality score (SS) > or = 9 and 5 controls with SS 3/4 4 participated in the study. The participants took saliva samples at home. Samples we...
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| Format: | Article in Journal/Newspaper |
| Language: | English |
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Atypon
2001
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| Online Access: | https://pubmed.ncbi.nlm.nih.gov/11768433 |
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ftpubmed:11768433 2024-09-15T18:02:07+00:00 Melatonin secretion in SAD patients and healthy subjects matched with respect to age and sex. Káradóttir, R Axelsson, J 2001 Nov https://pubmed.ncbi.nlm.nih.gov/11768433 eng eng Atypon https://pubmed.ncbi.nlm.nih.gov/11768433 Int J Circumpolar Health ISSN:1239-9736 Volume:60 Issue:4 Journal Article 2001 ftpubmed 2024-07-24T16:03:00Z Among the competing hypotheses concerning the aetiology of SAD is the melatonin hypothesis, which is the target of this study. 5 test subjects with SPAQ seasonality score (SS) > or = 9 and 5 controls with SS 3/4 4 participated in the study. The participants took saliva samples at home. Samples were collected 4 times a day for 3 days in March, 1999. Melatonin concentrations were determined by RIA. No significant differences in circadian rhythms were found between the groups; i.e. the curves for both groups ran parallel. However the concentrations of melatonin in the SAD patients were found to be on average 2.4 times as high as in the control group; the difference is significant at p<0.001. Our results support the melatonin hypothesis. Article in Journal/Newspaper Circumpolar Health PubMed Central (PMC) |
| institution |
Open Polar |
| collection |
PubMed Central (PMC) |
| op_collection_id |
ftpubmed |
| language |
English |
| description |
Among the competing hypotheses concerning the aetiology of SAD is the melatonin hypothesis, which is the target of this study. 5 test subjects with SPAQ seasonality score (SS) > or = 9 and 5 controls with SS 3/4 4 participated in the study. The participants took saliva samples at home. Samples were collected 4 times a day for 3 days in March, 1999. Melatonin concentrations were determined by RIA. No significant differences in circadian rhythms were found between the groups; i.e. the curves for both groups ran parallel. However the concentrations of melatonin in the SAD patients were found to be on average 2.4 times as high as in the control group; the difference is significant at p<0.001. Our results support the melatonin hypothesis. |
| format |
Article in Journal/Newspaper |
| author |
Káradóttir, R Axelsson, J |
| spellingShingle |
Káradóttir, R Axelsson, J Melatonin secretion in SAD patients and healthy subjects matched with respect to age and sex. |
| author_facet |
Káradóttir, R Axelsson, J |
| author_sort |
Káradóttir, R |
| title |
Melatonin secretion in SAD patients and healthy subjects matched with respect to age and sex. |
| title_short |
Melatonin secretion in SAD patients and healthy subjects matched with respect to age and sex. |
| title_full |
Melatonin secretion in SAD patients and healthy subjects matched with respect to age and sex. |
| title_fullStr |
Melatonin secretion in SAD patients and healthy subjects matched with respect to age and sex. |
| title_full_unstemmed |
Melatonin secretion in SAD patients and healthy subjects matched with respect to age and sex. |
| title_sort |
melatonin secretion in sad patients and healthy subjects matched with respect to age and sex. |
| publisher |
Atypon |
| publishDate |
2001 |
| url |
https://pubmed.ncbi.nlm.nih.gov/11768433 |
| genre |
Circumpolar Health |
| genre_facet |
Circumpolar Health |
| op_source |
Int J Circumpolar Health ISSN:1239-9736 Volume:60 Issue:4 |
| op_relation |
https://pubmed.ncbi.nlm.nih.gov/11768433 |
| _version_ |
1810439283692011520 |