A glucosephosphate isomerase inhibitor of seasonal occurrence in cod (Gadus morhua) and other fish.

• Published in: Journal of the Marine Biological Association of the United Kingdom
• Main Author: Dando, P. R.
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: 1969
• Subjects: Marine Sciences; Gadus morhua
• Online Access: http://plymsea.ac.uk/id/eprint/9749/; https://doi.org/10.1017/S002531540003602X

A heat-stable inhibitor of glucosephosphate isomerase (D-glucose-6-phosphate ketol-isomerase, E.C. 5.3.1.9) has been found in tissues of the cod (Gadus morhua L.). The inhibitor occurred in cod in the Plymouth area from February to mid-April in 1967 and from mid-March to mid-April in 1968. Gel filtration studies indicate that the inhibitory component of cod muscle has a molecular weight of less than 1500. A similar inhibitor has been found in red mullet {Mullus surmuletus L.),megrim (Lepidorhombus whiff-iagonis Walbaum) and greater forkbeard (Urophycis blennoides Briinnich). The inhibitor is of a seasonal nature in these fish also and may be linked with the spawning cycle.