1H NMR metabolomics reveals contrasting response by male and female mussels exposed to reduced seawater pH, increased temperature and a pathogen
Human activities are fundamentally altering the chemistry of the world's oceans. Ocean acidification (OA) is occurring against a background of warming and an increasing occurrence of disease outbreaks, posing a significant threat to marine organisms, communities, and ecosystems. In the current...
Published in: | Environmental Science & Technology |
---|---|
Main Authors: | , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | unknown |
Published: |
2014
|
Subjects: | |
Online Access: | http://plymsea.ac.uk/id/eprint/5973/ https://doi.org/10.1021/es501601w |
id |
ftplymouthml:oai:plymsea.ac.uk:5973 |
---|---|
record_format |
openpolar |
spelling |
ftplymouthml:oai:plymsea.ac.uk:5973 2023-05-15T17:51:20+02:00 1H NMR metabolomics reveals contrasting response by male and female mussels exposed to reduced seawater pH, increased temperature and a pathogen Ellis, RP Spicer, JI Byrne, J Sommer, U Viant, MR White, DA Widdicombe, S 2014-06-17 http://plymsea.ac.uk/id/eprint/5973/ https://doi.org/10.1021/es501601w unknown Ellis, RP; Spicer, JI; Byrne, J; Sommer, U; Viant, MR; White, DA; Widdicombe, S. 2014 1H NMR metabolomics reveals contrasting response by male and female mussels exposed to reduced seawater pH, increased temperature and a pathogen. Environmental Science & Technology, 48 (12). 7044-52. https://doi.org/10.1021/es501601w <https://doi.org/10.1021/es501601w> Biology Earth Sciences Ecology and Environment Publication - Article PeerReviewed 2014 ftplymouthml https://doi.org/10.1021/es501601w 2022-09-13T05:48:28Z Human activities are fundamentally altering the chemistry of the world's oceans. Ocean acidification (OA) is occurring against a background of warming and an increasing occurrence of disease outbreaks, posing a significant threat to marine organisms, communities, and ecosystems. In the current study, (1)H NMR spectroscopy was used to investigate the response of the blue mussel, Mytilus edulis, to a 90-day exposure to reduced seawater pH and increased temperature, followed by a subsequent pathogenic challenge. Analysis of the metabolome revealed significant differences between male and female organisms. Furthermore, males and females are shown to respond differently to environmental stress. While males were significantly affected by reduced seawater pH, increased temperature, and a bacterial challenge, it was only a reduction in seawater pH that impacted females. Despite impacting males and females differently, stressors seem to act via a generalized stress response impacting both energy metabolism and osmotic balance in both sexes. This study therefore has important implications for the interpretation of metabolomic data in mussels, as well as the impact of environmental stress in marine invertebrates in general. Article in Journal/Newspaper Ocean acidification Plymouth Marine Science Electronic Archive (PlyMSEA - Plymouth Marine Laboratory, PML) Environmental Science & Technology 48 12 7044 7052 |
institution |
Open Polar |
collection |
Plymouth Marine Science Electronic Archive (PlyMSEA - Plymouth Marine Laboratory, PML) |
op_collection_id |
ftplymouthml |
language |
unknown |
topic |
Biology Earth Sciences Ecology and Environment |
spellingShingle |
Biology Earth Sciences Ecology and Environment Ellis, RP Spicer, JI Byrne, J Sommer, U Viant, MR White, DA Widdicombe, S 1H NMR metabolomics reveals contrasting response by male and female mussels exposed to reduced seawater pH, increased temperature and a pathogen |
topic_facet |
Biology Earth Sciences Ecology and Environment |
description |
Human activities are fundamentally altering the chemistry of the world's oceans. Ocean acidification (OA) is occurring against a background of warming and an increasing occurrence of disease outbreaks, posing a significant threat to marine organisms, communities, and ecosystems. In the current study, (1)H NMR spectroscopy was used to investigate the response of the blue mussel, Mytilus edulis, to a 90-day exposure to reduced seawater pH and increased temperature, followed by a subsequent pathogenic challenge. Analysis of the metabolome revealed significant differences between male and female organisms. Furthermore, males and females are shown to respond differently to environmental stress. While males were significantly affected by reduced seawater pH, increased temperature, and a bacterial challenge, it was only a reduction in seawater pH that impacted females. Despite impacting males and females differently, stressors seem to act via a generalized stress response impacting both energy metabolism and osmotic balance in both sexes. This study therefore has important implications for the interpretation of metabolomic data in mussels, as well as the impact of environmental stress in marine invertebrates in general. |
format |
Article in Journal/Newspaper |
author |
Ellis, RP Spicer, JI Byrne, J Sommer, U Viant, MR White, DA Widdicombe, S |
author_facet |
Ellis, RP Spicer, JI Byrne, J Sommer, U Viant, MR White, DA Widdicombe, S |
author_sort |
Ellis, RP |
title |
1H NMR metabolomics reveals contrasting response by male and female mussels exposed to reduced seawater pH, increased temperature and a pathogen |
title_short |
1H NMR metabolomics reveals contrasting response by male and female mussels exposed to reduced seawater pH, increased temperature and a pathogen |
title_full |
1H NMR metabolomics reveals contrasting response by male and female mussels exposed to reduced seawater pH, increased temperature and a pathogen |
title_fullStr |
1H NMR metabolomics reveals contrasting response by male and female mussels exposed to reduced seawater pH, increased temperature and a pathogen |
title_full_unstemmed |
1H NMR metabolomics reveals contrasting response by male and female mussels exposed to reduced seawater pH, increased temperature and a pathogen |
title_sort |
1h nmr metabolomics reveals contrasting response by male and female mussels exposed to reduced seawater ph, increased temperature and a pathogen |
publishDate |
2014 |
url |
http://plymsea.ac.uk/id/eprint/5973/ https://doi.org/10.1021/es501601w |
genre |
Ocean acidification |
genre_facet |
Ocean acidification |
op_relation |
Ellis, RP; Spicer, JI; Byrne, J; Sommer, U; Viant, MR; White, DA; Widdicombe, S. 2014 1H NMR metabolomics reveals contrasting response by male and female mussels exposed to reduced seawater pH, increased temperature and a pathogen. Environmental Science & Technology, 48 (12). 7044-52. https://doi.org/10.1021/es501601w <https://doi.org/10.1021/es501601w> |
op_doi |
https://doi.org/10.1021/es501601w |
container_title |
Environmental Science & Technology |
container_volume |
48 |
container_issue |
12 |
container_start_page |
7044 |
op_container_end_page |
7052 |
_version_ |
1766158439429439488 |