Prevalence of chronic obstructive pulmonary disease in China - A large, population-based survey

• Main Authors: Zhong, Nanshan, Wang, Chen, Yao, Wanzhen, Chen, Ping, Kang, Jian, Huang, Shaoguang, Chen, Baoyuan, Wang, Changzheng, Ni, Diantao, Zhou, Yumin, Liu, Shengming, Wang, Xiaoping, Wang, Dali, Lu, Jiachun, Zheng, Jingping, Ran, Pixin
• Other Authors: Ran, P (reprint author), Guangzhou Med Coll, Affiliated Hosp 1, Guangzhou Inst Resp Dis, 151 Yanjiang Rd, Guangzhou 510120, Guangdong, Peoples R China., Guangzhou Med Coll, Affiliated Hosp 1, Guangzhou Inst Resp Dis, Guangzhou 510120, Guangdong, Peoples R China., Capital Univ Med Sci, Beijing Chaoyang Hosp, Beijing Inst Resp Med, Beijing, Peoples R China., Peking Univ, Hosp 3, Beijing 100871, Peoples R China., Shenyang Mil Gen Hosp, Shenyang, Liaoning, Peoples R China., China Med Univ, Affiliated Hosp 1, Shenyang, Liaoning, Peoples R China., Shanghai Jiao Tong Univ, Ruijing Hosp, Shanghai 200030, Peoples R China., Tianjin Med Univ, Gen Hosp, Tianjin, Peoples R China., Third Mil Med Univ, Xinqiao Hosp, Chongqing, Peoples R China., Fourth Mil Med Univ, Xijing Hosp, Xian 710032, Shanxi, Peoples R China., Jinan Univ, Affiliated Hosp 1, Guangzhou, Guangdong, Peoples R China., First Municipal People Hosp Shaoguan, Shaoguan, Guangdong, Peoples R China., Second Hosp Liwan Dist Guangzhou, Guangzhou, Guangdong, Peoples R China., Guangzhou Med Coll, Dept Epidemiol, Guangzhou, Guangdong, Peoples R China., Guangzhou Med Coll, Affiliated Hosp 1, Guangzhou Inst Resp Dis, 151 Yanjiang Rd, Guangzhou 510120, Guangdong, Peoples R China.
• Format: Journal/Newspaper
• Language: English
• Published: 美国呼吸道与危重症监护医学杂志 2007
• Subjects: chronic obstructive pulmonary disease; prevalence; epidemiology; cross-sectional studies; GOLD; LUNG-DISEASE; COPD PREVALENCE; NORTHERN SWEDEN; GLOBAL BURDEN; SMOKING; UNDERDIAGNOSIS; SAMPLE; Northern Sweden
• Online Access: https://hdl.handle.net/20.500.11897/398972; https://doi.org/10.1164/rccm.200612-17490C

Rationale: The prevalence of chronic obstructive pulmonary disease (COPD) in China is largely unknown. Objectives: To obtain the COPD prevalence in China through a largepopulation, spirometry-based, cross-sectional survey of COPD. Methods: Urban and rural population-based cluster samples were randomly selected from seven provinces/cities. All residents 40years of age or older in the selected clusters were interviewed with a standardized questionnaire revised from the international BOLD (Burden of Obstructive Lung Diseases) study. Spirometry was performed on all eligible participants. Patients with airflow limitation (FEV1/FVC < 0.70) were further examined by post-bronchodilator spirometry, chest radiograph, and electrocardiogram. Post-bronchodilator FEV1/ FVC of less than 70%was defined as the diagnostic criterion of COPD. Measurements and Main Results: Among 25,627 sampling subjects, 20,245 participants completed the questionnaire and spirometry (response rate, 79.0%). The overall prevalence of COPD was 8.2% (men, 12.4%; women, 5.1%). The prevalence of COPD was significantly higher in rural residents, elderly patients, smokers, in those with lower body mass index, less education, and poor ventilation in the kitchen, in those who were exposed to occupational dusts or biomass fuels, and in those with pulmonary problems in childhood and family history of pulmonary diseases. Among the patients who had COPD, 35.3% were asymptomatic; only 35.1 % reported lifetime diagnosis of bronchitis, emphysema, or other COPD; and only 6.5% have been tested with spirometry. Conclusions: COPD is prevalent in individuals 40 years of age or older in China. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000250136400007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 Critical Care Medicine Respiratory System SCI(E) 237 ARTICLE 8 753-760 176