Permafrost as a potential pathogen reservoir

• Published in: One Earth
• Main Authors: Wu, Ruonan, Trubl, Gareth, Taş, Neslihan, Jansson, Janet K.
• Language: unknown
• Published: 2023
• Subjects: 54 ENVIRONMENTAL SCIENCES; Arctic; Climate change; Human health; permafrost
• Online Access: http://www.osti.gov/servlets/purl/1876982; https://www.osti.gov/biblio/1876982; https://doi.org/10.1016/j.oneear.2022.03.010

The Arctic is currently warming at unprecedented rates because of global climate change, resulting in thawing of large tracts of permafrost soil. A great challenge is understanding the implications of permafrost thaw on human health and the environment. Permafrost is a reservoir of mostly uncharacterized microorganisms and viruses, many of which could be viable. Given our limited knowledge of permafrost-resident microbes, we also lack the basis to judge whether they pose risks to humans, animals, and plants. In this review, we delve into features of permafrost as a microbial habitat and discuss what is known about the potential for microbial pathogens to emerge in a warming climate as permafrost thaws. This review has broader implications for human health and ecosystem sustainability in the new Arctic environment that will emerge from a thawed permafrost landscape.