Lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study
Introduction Cardiovascular disease (CVD) is a leading cause of death and disability and living in areas with low socio-economic status (SES) is associated with increased risk of CVD. Lifestyle factors such as smoking, physical inactivity, an unhealthy diet and harmful alcohol use are main risk fact...
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ftoslouniv:oai:www.duo.uio.no:10852/97671 2023-05-15T18:34:18+02:00 Lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study ENEngelskEnglishLifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study Tiwari, Sweta Cerin, Ester Wilsgaard, Tom Løvsletten, Ola Njølstad, Inger Grimsgaard, Sameline Hopstock, Laila Arnesdatter Schirmer, Henrik Rosengren, Annika Kristoffersen, Kathrine Løchen, Maja-Lisa 2022-10-17T18:35:00Z http://hdl.handle.net/10852/97671 https://doi.org/10.1016/j.ssmph.2022.101241 EN eng NFR/289440 Tiwari, Sweta Cerin, Ester Wilsgaard, Tom Løvsletten, Ola Njølstad, Inger Grimsgaard, Sameline Hopstock, Laila Arnesdatter Schirmer, Henrik Rosengren, Annika Kristoffersen, Kathrine Løchen, Maja-Lisa . Lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study. SSM - Population Health. 2022, 19 http://hdl.handle.net/10852/97671 2062223 info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=SSM - Population Health&rft.volume=19&rft.spage=&rft.date=2022 SSM - Population Health 19 0 https://doi.org/10.1016/j.ssmph.2022.101241 Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/ CC-BY 2352-8273 Journal article Tidsskriftartikkel Peer reviewed PublishedVersion 2022 ftoslouniv https://doi.org/10.1016/j.ssmph.2022.101241 2022-11-23T23:35:58Z Introduction Cardiovascular disease (CVD) is a leading cause of death and disability and living in areas with low socio-economic status (SES) is associated with increased risk of CVD. Lifestyle factors such as smoking, physical inactivity, an unhealthy diet and harmful alcohol use are main risk factors that contribute to other modifiable risk factors, such as hypertension, raised blood cholesterol, obesity, and diabetes. The potential impact of area-level socio-economic status (ASES) on metabolic CVD risk factors via lifestyle behaviors independent of individual SES has not been investigated previously. Aims To estimate associations of ASES with CVD risk factors and the mediating role of lifestyle behaviors independent of individual-level SES. Methods In this cross-sectional study, we included 19,415 participants (52% women) from the seventh survey of the Tromsø Study (2015–2016) (Tromsø7). The exposure variable ASES was created by aggregating individual-level SES variables (education, income, housing ownership) at the geographical subdivision level. Individual-level SES data and geographical subdivision of Tromsø municipality (36 areas) were obtained from Statistics Norway. Variables from questionnaires and clinical examinations obtained from Tromsø7 were used as mediators (smoking, snuff, alcohol, and physical activity), while the outcome variables were body mass index (BMI), total/high-density lipoprotein (HDL) cholesterol ratio, waist circumference, hypertension, diabetes. Mediation and mediated moderation analysis were performed with age as a moderator, stratified by sex. Results ASES was significantly associated with all outcome variables. CVD risk factor level declined with an increase in ASES. These associations were mediated by differences in smoking habits, alcohol use and physical activity. The associations of ASES with total/HDL cholesterol ratio and waist circumference (women) were moderated by age, and the moderating effects were mediated by smoking and physical activity in both sexes. The largest ... Article in Journal/Newspaper Tromsø Universitet i Oslo: Digitale utgivelser ved UiO (DUO) Norway Tromsø SSM - Population Health 19 101241 |
institution |
Open Polar |
collection |
Universitet i Oslo: Digitale utgivelser ved UiO (DUO) |
op_collection_id |
ftoslouniv |
language |
English |
description |
Introduction Cardiovascular disease (CVD) is a leading cause of death and disability and living in areas with low socio-economic status (SES) is associated with increased risk of CVD. Lifestyle factors such as smoking, physical inactivity, an unhealthy diet and harmful alcohol use are main risk factors that contribute to other modifiable risk factors, such as hypertension, raised blood cholesterol, obesity, and diabetes. The potential impact of area-level socio-economic status (ASES) on metabolic CVD risk factors via lifestyle behaviors independent of individual SES has not been investigated previously. Aims To estimate associations of ASES with CVD risk factors and the mediating role of lifestyle behaviors independent of individual-level SES. Methods In this cross-sectional study, we included 19,415 participants (52% women) from the seventh survey of the Tromsø Study (2015–2016) (Tromsø7). The exposure variable ASES was created by aggregating individual-level SES variables (education, income, housing ownership) at the geographical subdivision level. Individual-level SES data and geographical subdivision of Tromsø municipality (36 areas) were obtained from Statistics Norway. Variables from questionnaires and clinical examinations obtained from Tromsø7 were used as mediators (smoking, snuff, alcohol, and physical activity), while the outcome variables were body mass index (BMI), total/high-density lipoprotein (HDL) cholesterol ratio, waist circumference, hypertension, diabetes. Mediation and mediated moderation analysis were performed with age as a moderator, stratified by sex. Results ASES was significantly associated with all outcome variables. CVD risk factor level declined with an increase in ASES. These associations were mediated by differences in smoking habits, alcohol use and physical activity. The associations of ASES with total/HDL cholesterol ratio and waist circumference (women) were moderated by age, and the moderating effects were mediated by smoking and physical activity in both sexes. The largest ... |
format |
Article in Journal/Newspaper |
author |
Tiwari, Sweta Cerin, Ester Wilsgaard, Tom Løvsletten, Ola Njølstad, Inger Grimsgaard, Sameline Hopstock, Laila Arnesdatter Schirmer, Henrik Rosengren, Annika Kristoffersen, Kathrine Løchen, Maja-Lisa |
spellingShingle |
Tiwari, Sweta Cerin, Ester Wilsgaard, Tom Løvsletten, Ola Njølstad, Inger Grimsgaard, Sameline Hopstock, Laila Arnesdatter Schirmer, Henrik Rosengren, Annika Kristoffersen, Kathrine Løchen, Maja-Lisa Lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study |
author_facet |
Tiwari, Sweta Cerin, Ester Wilsgaard, Tom Løvsletten, Ola Njølstad, Inger Grimsgaard, Sameline Hopstock, Laila Arnesdatter Schirmer, Henrik Rosengren, Annika Kristoffersen, Kathrine Løchen, Maja-Lisa |
author_sort |
Tiwari, Sweta |
title |
Lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study |
title_short |
Lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study |
title_full |
Lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study |
title_fullStr |
Lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study |
title_full_unstemmed |
Lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study |
title_sort |
lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. the tromsø study |
publishDate |
2022 |
url |
http://hdl.handle.net/10852/97671 https://doi.org/10.1016/j.ssmph.2022.101241 |
geographic |
Norway Tromsø |
geographic_facet |
Norway Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_source |
2352-8273 |
op_relation |
NFR/289440 Tiwari, Sweta Cerin, Ester Wilsgaard, Tom Løvsletten, Ola Njølstad, Inger Grimsgaard, Sameline Hopstock, Laila Arnesdatter Schirmer, Henrik Rosengren, Annika Kristoffersen, Kathrine Løchen, Maja-Lisa . Lifestyle factors as mediators of area-level socio-economic differentials in cardiovascular disease risk factors. The Tromsø Study. SSM - Population Health. 2022, 19 http://hdl.handle.net/10852/97671 2062223 info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=SSM - Population Health&rft.volume=19&rft.spage=&rft.date=2022 SSM - Population Health 19 0 https://doi.org/10.1016/j.ssmph.2022.101241 |
op_rights |
Attribution 4.0 International https://creativecommons.org/licenses/by/4.0/ |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1016/j.ssmph.2022.101241 |
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SSM - Population Health |
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19 |
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101241 |
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