Adherence to prescription guidelines and achievement of treatment goals among persons with coronary heart disease in Tromsø 7
Background Adherence to clinical practice guidelines for coronary heart disease (CHD) reduces morbidity, mortality and treatment costs. We aimed to describe and compare adherence to prescription guidelines for persons with CHD, and explore its association with treatment goal achievement. Method We i...
Published in: | BMC Cardiovascular Disorders |
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ftoslouniv:oai:www.duo.uio.no:10852/82631 2023-05-15T18:34:29+02:00 Adherence to prescription guidelines and achievement of treatment goals among persons with coronary heart disease in Tromsø 7 Pedersen, Elisabeth Garcia, Beate H Halvorsen, Kjell H Eggen, Anne E Schirmer, Henrik Waaseth, Marit 2021 http://hdl.handle.net/10852/82631 http://urn.nb.no/URN:NBN:no-85481 https://doi.org/10.1186/s12872-021-01866-1 eng eng http://urn.nb.no/URN:NBN:no-85481 BMC Cardiovascular Disorders. 2021 Jan 21;21(1):44 http://hdl.handle.net/10852/82631 1903283 https://doi.org/10.1186/s12872-021-01866-1 URN:NBN:no-85481 Fulltext https://www.duo.uio.no/bitstream/handle/10852/82631/1/12872_2021_Article_1866.pdf Fulltext https://www.duo.uio.no/bitstream/handle/10852/82631/4/Correction-12872_2021_Article_2214.pdf The Author(s) Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ CC-BY Journal article Tidsskriftartikkel Peer reviewed PublishedVersion 2021 ftoslouniv https://doi.org/10.1186/s12872-021-01866-1 2021-09-08T22:31:37Z Background Adherence to clinical practice guidelines for coronary heart disease (CHD) reduces morbidity, mortality and treatment costs. We aimed to describe and compare adherence to prescription guidelines for persons with CHD, and explore its association with treatment goal achievement. Method We included all participants reporting myocardial infarction, angina, percutaneous coronary intervention and/or coronary artery bypass surgery in the seventh wave of the Tromsø Study (2015–2016, n = 1483). Medication use and treatment goal measures (blood pressure, low-density lipoprotein (LDL)-cholesterol and HbA1c) were compared to clinical practice guidelines on secondary CHD prevention. Propensity score matched logistic regression was used to assess the association between the use of antihypertensive drugs and achievement of treatment goal for blood pressure, and the use of lipid-lowering drugs (LLDs) and achievement of treatment goal for LDL-cholesterol. Results The prevalence of pharmacological CHD treatment was 76% for LLDs, 72% for antihypertensive drugs and 66% for acetylsalicylic acid. The blood pressure goal (< 140/90 mmHg, < 140/80 mmHg if diabetic) was achieved by 58% and the LDL-cholesterol goal (< 1.8 mmol/l or < 70 mg/dL) by 9%. There was a strong association between using LLDs and achieving the treatment goal for LDL-cholesterol (OR 14.0, 95% CI 3.6–54.7), but not between using antihypertensive drugs and blood pressure goal achievement (OR 1.4, 95% CI 0.7–2.7). Conclusion Treatment goal achievement of LDL-cholesterol and blood pressure was low, despite the relatively high use of LLDs and antihypertensive drugs. Further research is needed to find the proper actions to increase achievement of the treatment goals. Article in Journal/Newspaper Tromsø Universitet i Oslo: Digitale utgivelser ved UiO (DUO) Tromsø BMC Cardiovascular Disorders 21 1 |
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Universitet i Oslo: Digitale utgivelser ved UiO (DUO) |
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English |
description |
Background Adherence to clinical practice guidelines for coronary heart disease (CHD) reduces morbidity, mortality and treatment costs. We aimed to describe and compare adherence to prescription guidelines for persons with CHD, and explore its association with treatment goal achievement. Method We included all participants reporting myocardial infarction, angina, percutaneous coronary intervention and/or coronary artery bypass surgery in the seventh wave of the Tromsø Study (2015–2016, n = 1483). Medication use and treatment goal measures (blood pressure, low-density lipoprotein (LDL)-cholesterol and HbA1c) were compared to clinical practice guidelines on secondary CHD prevention. Propensity score matched logistic regression was used to assess the association between the use of antihypertensive drugs and achievement of treatment goal for blood pressure, and the use of lipid-lowering drugs (LLDs) and achievement of treatment goal for LDL-cholesterol. Results The prevalence of pharmacological CHD treatment was 76% for LLDs, 72% for antihypertensive drugs and 66% for acetylsalicylic acid. The blood pressure goal (< 140/90 mmHg, < 140/80 mmHg if diabetic) was achieved by 58% and the LDL-cholesterol goal (< 1.8 mmol/l or < 70 mg/dL) by 9%. There was a strong association between using LLDs and achieving the treatment goal for LDL-cholesterol (OR 14.0, 95% CI 3.6–54.7), but not between using antihypertensive drugs and blood pressure goal achievement (OR 1.4, 95% CI 0.7–2.7). Conclusion Treatment goal achievement of LDL-cholesterol and blood pressure was low, despite the relatively high use of LLDs and antihypertensive drugs. Further research is needed to find the proper actions to increase achievement of the treatment goals. |
format |
Article in Journal/Newspaper |
author |
Pedersen, Elisabeth Garcia, Beate H Halvorsen, Kjell H Eggen, Anne E Schirmer, Henrik Waaseth, Marit |
spellingShingle |
Pedersen, Elisabeth Garcia, Beate H Halvorsen, Kjell H Eggen, Anne E Schirmer, Henrik Waaseth, Marit Adherence to prescription guidelines and achievement of treatment goals among persons with coronary heart disease in Tromsø 7 |
author_facet |
Pedersen, Elisabeth Garcia, Beate H Halvorsen, Kjell H Eggen, Anne E Schirmer, Henrik Waaseth, Marit |
author_sort |
Pedersen, Elisabeth |
title |
Adherence to prescription guidelines and achievement of treatment goals among persons with coronary heart disease in Tromsø 7 |
title_short |
Adherence to prescription guidelines and achievement of treatment goals among persons with coronary heart disease in Tromsø 7 |
title_full |
Adherence to prescription guidelines and achievement of treatment goals among persons with coronary heart disease in Tromsø 7 |
title_fullStr |
Adherence to prescription guidelines and achievement of treatment goals among persons with coronary heart disease in Tromsø 7 |
title_full_unstemmed |
Adherence to prescription guidelines and achievement of treatment goals among persons with coronary heart disease in Tromsø 7 |
title_sort |
adherence to prescription guidelines and achievement of treatment goals among persons with coronary heart disease in tromsø 7 |
publishDate |
2021 |
url |
http://hdl.handle.net/10852/82631 http://urn.nb.no/URN:NBN:no-85481 https://doi.org/10.1186/s12872-021-01866-1 |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
http://urn.nb.no/URN:NBN:no-85481 BMC Cardiovascular Disorders. 2021 Jan 21;21(1):44 http://hdl.handle.net/10852/82631 1903283 https://doi.org/10.1186/s12872-021-01866-1 URN:NBN:no-85481 Fulltext https://www.duo.uio.no/bitstream/handle/10852/82631/1/12872_2021_Article_1866.pdf Fulltext https://www.duo.uio.no/bitstream/handle/10852/82631/4/Correction-12872_2021_Article_2214.pdf |
op_rights |
The Author(s) Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1186/s12872-021-01866-1 |
container_title |
BMC Cardiovascular Disorders |
container_volume |
21 |
container_issue |
1 |
_version_ |
1766219246439759872 |