Predictors of early mortality after transcatheter aortic valve implantation
To investigate whether preoperative echocardiographic evaluation of ventricular function, especially right ventricular systolic and diastolic parameters including speckle-tracking analysis, could aid in the prediction of 30-day mortality after transcatheter aortic valve implantation (TAVI) in patien...
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ftoslouniv:oai:www.duo.uio.no:10852/73972 2023-05-15T17:39:22+02:00 Predictors of early mortality after transcatheter aortic valve implantation Kjønås, Didrik Dahle, Gry Schirmer, Henrik Malm, Siri Eidet, Jo Aaberge, Lars Steigen, Terje Aakhus, Svend Busund, Rolf Rösner, Assami 2019-06-24T10:44:49Z http://hdl.handle.net/10852/73972 http://urn.nb.no/URN:NBN:no-77079 https://doi.org/10.1136/openhrt-2018-000936 EN eng BMJ Publishing Group http://urn.nb.no/URN:NBN:no-77079 Kjønås, Didrik Dahle, Gry Schirmer, Henrik Malm, Siri Eidet, Jo Aaberge, Lars Steigen, Terje Aakhus, Svend Busund, Rolf Rösner, Assami . Predictors of early mortality after transcatheter aortic valve implantation. Open heart. 2019, 6(1) http://hdl.handle.net/10852/73972 1707170 info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Open heart&rft.volume=6&rft.spage=&rft.date=2019 Open heart 6 1 https://doi.org/10.1136/openhrt-2018-000936 URN:NBN:no-77079 Fulltext https://www.duo.uio.no/bitstream/handle/10852/73972/1/article27416.pdf Attribution-NonCommercial 4.0 International https://creativecommons.org/licenses/by-nc/4.0/ CC-BY-NC 2053-3624 Journal article Tidsskriftartikkel Peer reviewed PublishedVersion 2019 ftoslouniv https://doi.org/10.1136/openhrt-2018-000936 2020-06-21T08:53:51Z To investigate whether preoperative echocardiographic evaluation of ventricular function, especially right ventricular systolic and diastolic parameters including speckle-tracking analysis, could aid in the prediction of 30-day mortality after transcatheter aortic valve implantation (TAVI) in patients with aortic stenosis.This is a prospective observational cohort study including 227 patients accepted for TAVI at the University Hospital of North Norway and Oslo University Hospital from February 2010 through June 2013. All patients underwent preoperative transthoracic echocardiography with retrospective speckle-tracking analysis. Primary endpoint was all-cause 30-day mortality.All-cause 30-day mortality was 8.7 % (n = 19). Independent predictors of 30-day mortality were systolic pulmonary arterial pressure (SPAP) > 60 mm Hg (HR: 7.7, 95% CI: 1.90 to 31.3), heart failure (HR: 2.9, 95% CI: 1.1 to 7.78), transapical access (HR: 3.8, 95% CI: 1.3 to 11.2), peripheral artery disease (HR: 6.0, 95% CI: 2.0 to 18.0) and body mass index (HR: 0.73, 95% CI: 0.61 to 0.87). C-statistic for the model generated was 0.91 (95% CI: 0.85 to 0.98). Besides elevated SPAP, no other echocardiographic measurements were found to be an independent predictor of early mortality.Except for elevated systolic pulmonary artery pressure, our data suggests that clinical rather than echocardiographic parameters are useful predictors of 30-day mortality after TAVI. Article in Journal/Newspaper North Norway Universitet i Oslo: Digitale utgivelser ved UiO (DUO) Norway Open Heart 6 1 e000936 |
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Open Polar |
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Universitet i Oslo: Digitale utgivelser ved UiO (DUO) |
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ftoslouniv |
language |
English |
description |
To investigate whether preoperative echocardiographic evaluation of ventricular function, especially right ventricular systolic and diastolic parameters including speckle-tracking analysis, could aid in the prediction of 30-day mortality after transcatheter aortic valve implantation (TAVI) in patients with aortic stenosis.This is a prospective observational cohort study including 227 patients accepted for TAVI at the University Hospital of North Norway and Oslo University Hospital from February 2010 through June 2013. All patients underwent preoperative transthoracic echocardiography with retrospective speckle-tracking analysis. Primary endpoint was all-cause 30-day mortality.All-cause 30-day mortality was 8.7 % (n = 19). Independent predictors of 30-day mortality were systolic pulmonary arterial pressure (SPAP) > 60 mm Hg (HR: 7.7, 95% CI: 1.90 to 31.3), heart failure (HR: 2.9, 95% CI: 1.1 to 7.78), transapical access (HR: 3.8, 95% CI: 1.3 to 11.2), peripheral artery disease (HR: 6.0, 95% CI: 2.0 to 18.0) and body mass index (HR: 0.73, 95% CI: 0.61 to 0.87). C-statistic for the model generated was 0.91 (95% CI: 0.85 to 0.98). Besides elevated SPAP, no other echocardiographic measurements were found to be an independent predictor of early mortality.Except for elevated systolic pulmonary artery pressure, our data suggests that clinical rather than echocardiographic parameters are useful predictors of 30-day mortality after TAVI. |
format |
Article in Journal/Newspaper |
author |
Kjønås, Didrik Dahle, Gry Schirmer, Henrik Malm, Siri Eidet, Jo Aaberge, Lars Steigen, Terje Aakhus, Svend Busund, Rolf Rösner, Assami |
spellingShingle |
Kjønås, Didrik Dahle, Gry Schirmer, Henrik Malm, Siri Eidet, Jo Aaberge, Lars Steigen, Terje Aakhus, Svend Busund, Rolf Rösner, Assami Predictors of early mortality after transcatheter aortic valve implantation |
author_facet |
Kjønås, Didrik Dahle, Gry Schirmer, Henrik Malm, Siri Eidet, Jo Aaberge, Lars Steigen, Terje Aakhus, Svend Busund, Rolf Rösner, Assami |
author_sort |
Kjønås, Didrik |
title |
Predictors of early mortality after transcatheter aortic valve implantation |
title_short |
Predictors of early mortality after transcatheter aortic valve implantation |
title_full |
Predictors of early mortality after transcatheter aortic valve implantation |
title_fullStr |
Predictors of early mortality after transcatheter aortic valve implantation |
title_full_unstemmed |
Predictors of early mortality after transcatheter aortic valve implantation |
title_sort |
predictors of early mortality after transcatheter aortic valve implantation |
publisher |
BMJ Publishing Group |
publishDate |
2019 |
url |
http://hdl.handle.net/10852/73972 http://urn.nb.no/URN:NBN:no-77079 https://doi.org/10.1136/openhrt-2018-000936 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
North Norway |
genre_facet |
North Norway |
op_source |
2053-3624 |
op_relation |
http://urn.nb.no/URN:NBN:no-77079 Kjønås, Didrik Dahle, Gry Schirmer, Henrik Malm, Siri Eidet, Jo Aaberge, Lars Steigen, Terje Aakhus, Svend Busund, Rolf Rösner, Assami . Predictors of early mortality after transcatheter aortic valve implantation. Open heart. 2019, 6(1) http://hdl.handle.net/10852/73972 1707170 info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Open heart&rft.volume=6&rft.spage=&rft.date=2019 Open heart 6 1 https://doi.org/10.1136/openhrt-2018-000936 URN:NBN:no-77079 Fulltext https://www.duo.uio.no/bitstream/handle/10852/73972/1/article27416.pdf |
op_rights |
Attribution-NonCommercial 4.0 International https://creativecommons.org/licenses/by-nc/4.0/ |
op_rightsnorm |
CC-BY-NC |
op_doi |
https://doi.org/10.1136/openhrt-2018-000936 |
container_title |
Open Heart |
container_volume |
6 |
container_issue |
1 |
container_start_page |
e000936 |
_version_ |
1766140131987685376 |