Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate
Background Left ventricular (LV) systolic and diastolic functions are important cardiovascular risk predictors in patients with hypertension. However, data on segmental, layer-specific strain, and diastolic strain rates in these patients are limited. The aim of this study was to investigate segmenta...
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ftoslouniv:oai:www.duo.uio.no:10852/103236 2023-09-05T13:17:53+02:00 Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate ENEngelskEnglishInfluence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate Kornev, Mikhail Hatice, Akay Caglayan Kudryavtsev, Alexander V Malyutina, Sofia Ryabikov, Andrew Schirmer, Henrik Rösner, Assami 2023-06-02T16:33:11Z http://hdl.handle.net/10852/103236 https://doi.org/10.1111/echo.15625 EN eng Kornev, Mikhail Hatice, Akay Caglayan Kudryavtsev, Alexander V Malyutina, Sofia Ryabikov, Andrew Schirmer, Henrik Rösner, Assami . Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate. Echocardiography. 2023 http://hdl.handle.net/10852/103236 2151383 info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Echocardiography&rft.volume=&rft.spage=&rft.date=2023 Echocardiography 40 7 623 633 0 https://doi.org/10.1111/echo.15625 Attribution-NonCommercial-NoDerivatives 4.0 International https://creativecommons.org/licenses/by-nc-nd/4.0/ 0742-2822 Journal article Tidsskriftartikkel Peer reviewed PublishedVersion 2023 ftoslouniv https://doi.org/10.1111/echo.15625 2023-08-16T22:38:51Z Background Left ventricular (LV) systolic and diastolic functions are important cardiovascular risk predictors in patients with hypertension. However, data on segmental, layer-specific strain, and diastolic strain rates in these patients are limited. The aim of this study was to investigate segmental two-dimensional strain rate imaging (SRI)-derived parameters to characterize LV systolic and diastolic function in hypertensive individuals compared with that in normotensive individuals. Methods The study sample comprised 1194 participants from the population-based Know Your Heart study in Arkhangelsk and Novosibirsk, Russia, and 1013 individuals from the Seventh Tromsø Study in Norway. The study population was divided into four subgroups: (A) healthy individuals with normal blood pressure (BP), (B) individuals on antihypertensive medication with normal BP, (C) individuals with systolic BP 140–159 mmHg and/or diastolic BP > 90 mm HG, and (D) individuals with systolic BP ≥160 mmHg. In addition to conventional echocardiographic parameters, global and segmental layer-specific strains and strain rates in early diastole and atrial contraction (SR E, SR A) were extracted. The strain and SR (S/SR) analysis included only segments without strain curve artifacts. Results With increasing BP, the systolic and diastolic global and segmental S/SR gradually decreased. SR E, a marker of impaired relaxation, showed the most distinctive differences between the groups. In normotensive controls and the three hypertension groups, all segmental parameters displayed apico-basal gradients, with the lowest S/SR in the basal septal and highest in apical segments. Only SR A did not differ between the segmental groups but increased gradually with increasing BP. End-systolic strain showed incremental epi-towards endocardial gradients, irrespective of the study group. Conclusion Arterial hypertension reduces global and segmental systolic and diastolic left ventricular S/SR parameters. Impaired relaxation determined by SR E is the dominant ... Article in Journal/Newspaper Arkhangelsk Tromsø Universitet i Oslo: Digitale utgivelser ved UiO (DUO) Norway Tromsø Echocardiography 40 7 623 633 |
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Open Polar |
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Universitet i Oslo: Digitale utgivelser ved UiO (DUO) |
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ftoslouniv |
language |
English |
description |
Background Left ventricular (LV) systolic and diastolic functions are important cardiovascular risk predictors in patients with hypertension. However, data on segmental, layer-specific strain, and diastolic strain rates in these patients are limited. The aim of this study was to investigate segmental two-dimensional strain rate imaging (SRI)-derived parameters to characterize LV systolic and diastolic function in hypertensive individuals compared with that in normotensive individuals. Methods The study sample comprised 1194 participants from the population-based Know Your Heart study in Arkhangelsk and Novosibirsk, Russia, and 1013 individuals from the Seventh Tromsø Study in Norway. The study population was divided into four subgroups: (A) healthy individuals with normal blood pressure (BP), (B) individuals on antihypertensive medication with normal BP, (C) individuals with systolic BP 140–159 mmHg and/or diastolic BP > 90 mm HG, and (D) individuals with systolic BP ≥160 mmHg. In addition to conventional echocardiographic parameters, global and segmental layer-specific strains and strain rates in early diastole and atrial contraction (SR E, SR A) were extracted. The strain and SR (S/SR) analysis included only segments without strain curve artifacts. Results With increasing BP, the systolic and diastolic global and segmental S/SR gradually decreased. SR E, a marker of impaired relaxation, showed the most distinctive differences between the groups. In normotensive controls and the three hypertension groups, all segmental parameters displayed apico-basal gradients, with the lowest S/SR in the basal septal and highest in apical segments. Only SR A did not differ between the segmental groups but increased gradually with increasing BP. End-systolic strain showed incremental epi-towards endocardial gradients, irrespective of the study group. Conclusion Arterial hypertension reduces global and segmental systolic and diastolic left ventricular S/SR parameters. Impaired relaxation determined by SR E is the dominant ... |
format |
Article in Journal/Newspaper |
author |
Kornev, Mikhail Hatice, Akay Caglayan Kudryavtsev, Alexander V Malyutina, Sofia Ryabikov, Andrew Schirmer, Henrik Rösner, Assami |
spellingShingle |
Kornev, Mikhail Hatice, Akay Caglayan Kudryavtsev, Alexander V Malyutina, Sofia Ryabikov, Andrew Schirmer, Henrik Rösner, Assami Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate |
author_facet |
Kornev, Mikhail Hatice, Akay Caglayan Kudryavtsev, Alexander V Malyutina, Sofia Ryabikov, Andrew Schirmer, Henrik Rösner, Assami |
author_sort |
Kornev, Mikhail |
title |
Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate |
title_short |
Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate |
title_full |
Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate |
title_fullStr |
Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate |
title_full_unstemmed |
Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate |
title_sort |
influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate |
publishDate |
2023 |
url |
http://hdl.handle.net/10852/103236 https://doi.org/10.1111/echo.15625 |
geographic |
Norway Tromsø |
geographic_facet |
Norway Tromsø |
genre |
Arkhangelsk Tromsø |
genre_facet |
Arkhangelsk Tromsø |
op_source |
0742-2822 |
op_relation |
Kornev, Mikhail Hatice, Akay Caglayan Kudryavtsev, Alexander V Malyutina, Sofia Ryabikov, Andrew Schirmer, Henrik Rösner, Assami . Influence of hypertension on systolic and diastolic left ventricular function including segmental strain and strain rate. Echocardiography. 2023 http://hdl.handle.net/10852/103236 2151383 info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Echocardiography&rft.volume=&rft.spage=&rft.date=2023 Echocardiography 40 7 623 633 0 https://doi.org/10.1111/echo.15625 |
op_rights |
Attribution-NonCommercial-NoDerivatives 4.0 International https://creativecommons.org/licenses/by-nc-nd/4.0/ |
op_doi |
https://doi.org/10.1111/echo.15625 |
container_title |
Echocardiography |
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40 |
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7 |
container_start_page |
623 |
op_container_end_page |
633 |
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1776198894362820608 |