6-O-glucose palmitate synthesis with lipase: Investigation of some key parameters

• Published in: Molecular Catalysis
• Main Authors: ARCENS, Dounia, GRAU, Etienne, GRELIER, Stéphane, CRAMAIL, Henri, PERUCH, Frédéric
• Format: Other/Unknown Material
• Language: English
• Published: Elsevier 2018
• Subjects: Glycolipids; GlycolipidsEnzymatic synthesisLipase; Lipase; Enzymatic synthesis; Chimie/Catalyse; Chimie/Chimie organique; Sciences du Vivant [q-bio]/Biochimie; Biologie Moléculaire/Biochimie [q-bio.BM]; Antarc*; Antarctica
• Online Access: https://oskar-bordeaux.fr/handle/20.500.12278/19805; https://doi.org/10.1016/j.mcat.2018.09.013

Fatty acid sugar esters represent an important class of non-ionic bio-based surfactants. They can be synthesized from vinyl fatty acids and sugars with enzyme as a catalyst. Herein, the influence of the solvent, the lipase and the temperature on a model reaction between vinyl palmitate and glucose via enzymatic catalysis has been investigated and the reaction conditions optimized. Full conversion into 6-O-glucose palmitate was reached in 40 h in acetonitrile starting from a reactant ratio 1:1, at only 5%-wt loading of lipase from Candida antarctica B (CALB) without the presence of molecular sieves.