Bioaccumulation of pharmaceuticals and stimulants in macrobenthic food web in the European Arctic as determined using stable isotope approach.
peer reviewed Although pharmaceuticals are increasingly detected in abiotic matrices in the Arctic, the accumulation of drugs in the resident biota and trophic transfer have not been yet examined. This study investigated the behaviour of several pharmaceuticals in the rocky-bottom, macrobenthic food...
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Format: | Article in Journal/Newspaper |
Language: | English |
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2023
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Online Access: | https://orbi.uliege.be/handle/2268/309257 https://doi.org/10.1016/j.scitotenv.2023.168557 |
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ftorbi:oai:orbi.ulg.ac.be:2268/309257 2024-10-13T14:04:47+00:00 Bioaccumulation of pharmaceuticals and stimulants in macrobenthic food web in the European Arctic as determined using stable isotope approach. Sokołowski, Adam Mordec, Marlena Caban, Magda Øverjordet, Ida Beathe Wielogórska, Ewa Włodarska-Kowalczuk, Maria Balazy, Piotr Chełchowski, Maciej Lepoint, Gilles FOCUS - Freshwater and OCeanic science Unit of reSearch - ULiège BE 2023-11-17 https://orbi.uliege.be/handle/2268/309257 https://doi.org/10.1016/j.scitotenv.2023.168557 en eng Elsevier BV https://api.elsevier.com/content/article/PII:S0048969723071851?httpAccept=text/xml urn:issn:0048-9697 urn:issn:1879-1026 https://orbi.uliege.be/handle/2268/309257 info:hdl:2268/309257 doi:10.1016/j.scitotenv.2023.168557 info:pmid:37979847 embargoed access http://purl.org/coar/access_right/c_f1cf info:eu-repo/semantics/embargoedAccess Science of the Total Environment, 909, 168557 (2023-11-17) Coastal zone European Arctic Macrobenthos Pharmaceuticals Stable isotopes Trophic transfer Pollution Waste Management and Disposal Environmental Chemistry Environmental Engineering Life sciences Aquatic sciences & oceanology Environmental sciences & ecology Zoology Sciences du vivant Sciences aquatiques & océanologie Sciences de l’environnement & écologie Zoologie journal article http://purl.org/coar/resource_type/c_6501 info:eu-repo/semantics/article peer reviewed 2023 ftorbi https://doi.org/10.1016/j.scitotenv.2023.168557 2024-09-27T07:01:42Z peer reviewed Although pharmaceuticals are increasingly detected in abiotic matrices in the Arctic, the accumulation of drugs in the resident biota and trophic transfer have not been yet examined. This study investigated the behaviour of several pharmaceuticals in the rocky-bottom, macrobenthic food web in the coastal zone of Isfjorden (western Spitsbergen) using stable isotope analyses (SIA) coupled with liquid chromatography-mass spectrometry (LC-MS/MS). Across 16 macroalgal and invertebrate species the highest average concentration was measured for ciprofloxacin (CIP) (on average 60.3 ng g-1 dw) followed by paracetamol (PCT) (51.3 ng g-1 dw) and nicotine (NIC) (37.8 ng g-1 dw). The biomagnification potential was assessed for six target compounds of 13 analytes detected that were quantified with a frequency > 50 % in biological samples. The trophic magnification factor (TMF) ranged between 0.3 and 2.8, and was significant for NIC and CIP. TMF < 1.0 for NIC (0.3; confidence interval, CI 0.1-0.5) indicated that the compound does not accumulate with trophic position. The dilution of pharmaceutical residues in the food web may result from limited intake with dietary route, poor assimilation efficiency and high biotransformation rates in benthic invertebrates. TMF for CIP (2.8, CI 1.2-6.4) suggests trophic magnification, a phenomenon observed previously for several antibiotics in freshwater food webs. Trophic transfer therefore plays a role in controlling concentration of CIP in the Arctic benthic communities and should be considered in environmental risk assessment. Biomagnification potential of diclofenac (DIC; 0.9, CI 0.5-1.7), carbamazepine (CBZ; 0.4, CI 0.1-2.1), caffeine (CAF; 0.9, CI 0.5-1.9) and PCT (1.3, CI 0.7-2.7) was not evident due to large 95 % confidence of their TMFs. This study provides the first evidence of drug bioaccumulation in the Arctic food web and indicates that behaviour of pharmaceuticals varies among target compounds. 14. Life below water Article in Journal/Newspaper Arctic Isfjord* Isfjorden Spitsbergen University of Liège: ORBi (Open Repository and Bibliography) Arctic Science of The Total Environment 909 168557 |
institution |
Open Polar |
collection |
University of Liège: ORBi (Open Repository and Bibliography) |
op_collection_id |
ftorbi |
language |
English |
topic |
Coastal zone European Arctic Macrobenthos Pharmaceuticals Stable isotopes Trophic transfer Pollution Waste Management and Disposal Environmental Chemistry Environmental Engineering Life sciences Aquatic sciences & oceanology Environmental sciences & ecology Zoology Sciences du vivant Sciences aquatiques & océanologie Sciences de l’environnement & écologie Zoologie |
spellingShingle |
Coastal zone European Arctic Macrobenthos Pharmaceuticals Stable isotopes Trophic transfer Pollution Waste Management and Disposal Environmental Chemistry Environmental Engineering Life sciences Aquatic sciences & oceanology Environmental sciences & ecology Zoology Sciences du vivant Sciences aquatiques & océanologie Sciences de l’environnement & écologie Zoologie Sokołowski, Adam Mordec, Marlena Caban, Magda Øverjordet, Ida Beathe Wielogórska, Ewa Włodarska-Kowalczuk, Maria Balazy, Piotr Chełchowski, Maciej Lepoint, Gilles Bioaccumulation of pharmaceuticals and stimulants in macrobenthic food web in the European Arctic as determined using stable isotope approach. |
topic_facet |
Coastal zone European Arctic Macrobenthos Pharmaceuticals Stable isotopes Trophic transfer Pollution Waste Management and Disposal Environmental Chemistry Environmental Engineering Life sciences Aquatic sciences & oceanology Environmental sciences & ecology Zoology Sciences du vivant Sciences aquatiques & océanologie Sciences de l’environnement & écologie Zoologie |
description |
peer reviewed Although pharmaceuticals are increasingly detected in abiotic matrices in the Arctic, the accumulation of drugs in the resident biota and trophic transfer have not been yet examined. This study investigated the behaviour of several pharmaceuticals in the rocky-bottom, macrobenthic food web in the coastal zone of Isfjorden (western Spitsbergen) using stable isotope analyses (SIA) coupled with liquid chromatography-mass spectrometry (LC-MS/MS). Across 16 macroalgal and invertebrate species the highest average concentration was measured for ciprofloxacin (CIP) (on average 60.3 ng g-1 dw) followed by paracetamol (PCT) (51.3 ng g-1 dw) and nicotine (NIC) (37.8 ng g-1 dw). The biomagnification potential was assessed for six target compounds of 13 analytes detected that were quantified with a frequency > 50 % in biological samples. The trophic magnification factor (TMF) ranged between 0.3 and 2.8, and was significant for NIC and CIP. TMF < 1.0 for NIC (0.3; confidence interval, CI 0.1-0.5) indicated that the compound does not accumulate with trophic position. The dilution of pharmaceutical residues in the food web may result from limited intake with dietary route, poor assimilation efficiency and high biotransformation rates in benthic invertebrates. TMF for CIP (2.8, CI 1.2-6.4) suggests trophic magnification, a phenomenon observed previously for several antibiotics in freshwater food webs. Trophic transfer therefore plays a role in controlling concentration of CIP in the Arctic benthic communities and should be considered in environmental risk assessment. Biomagnification potential of diclofenac (DIC; 0.9, CI 0.5-1.7), carbamazepine (CBZ; 0.4, CI 0.1-2.1), caffeine (CAF; 0.9, CI 0.5-1.9) and PCT (1.3, CI 0.7-2.7) was not evident due to large 95 % confidence of their TMFs. This study provides the first evidence of drug bioaccumulation in the Arctic food web and indicates that behaviour of pharmaceuticals varies among target compounds. 14. Life below water |
author2 |
FOCUS - Freshwater and OCeanic science Unit of reSearch - ULiège BE |
format |
Article in Journal/Newspaper |
author |
Sokołowski, Adam Mordec, Marlena Caban, Magda Øverjordet, Ida Beathe Wielogórska, Ewa Włodarska-Kowalczuk, Maria Balazy, Piotr Chełchowski, Maciej Lepoint, Gilles |
author_facet |
Sokołowski, Adam Mordec, Marlena Caban, Magda Øverjordet, Ida Beathe Wielogórska, Ewa Włodarska-Kowalczuk, Maria Balazy, Piotr Chełchowski, Maciej Lepoint, Gilles |
author_sort |
Sokołowski, Adam |
title |
Bioaccumulation of pharmaceuticals and stimulants in macrobenthic food web in the European Arctic as determined using stable isotope approach. |
title_short |
Bioaccumulation of pharmaceuticals and stimulants in macrobenthic food web in the European Arctic as determined using stable isotope approach. |
title_full |
Bioaccumulation of pharmaceuticals and stimulants in macrobenthic food web in the European Arctic as determined using stable isotope approach. |
title_fullStr |
Bioaccumulation of pharmaceuticals and stimulants in macrobenthic food web in the European Arctic as determined using stable isotope approach. |
title_full_unstemmed |
Bioaccumulation of pharmaceuticals and stimulants in macrobenthic food web in the European Arctic as determined using stable isotope approach. |
title_sort |
bioaccumulation of pharmaceuticals and stimulants in macrobenthic food web in the european arctic as determined using stable isotope approach. |
publisher |
Elsevier BV |
publishDate |
2023 |
url |
https://orbi.uliege.be/handle/2268/309257 https://doi.org/10.1016/j.scitotenv.2023.168557 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic Isfjord* Isfjorden Spitsbergen |
genre_facet |
Arctic Isfjord* Isfjorden Spitsbergen |
op_source |
Science of the Total Environment, 909, 168557 (2023-11-17) |
op_relation |
https://api.elsevier.com/content/article/PII:S0048969723071851?httpAccept=text/xml urn:issn:0048-9697 urn:issn:1879-1026 https://orbi.uliege.be/handle/2268/309257 info:hdl:2268/309257 doi:10.1016/j.scitotenv.2023.168557 info:pmid:37979847 |
op_rights |
embargoed access http://purl.org/coar/access_right/c_f1cf info:eu-repo/semantics/embargoedAccess |
op_doi |
https://doi.org/10.1016/j.scitotenv.2023.168557 |
container_title |
Science of The Total Environment |
container_volume |
909 |
container_start_page |
168557 |
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1812810447552774144 |