The BCCM/ULC collection to conserve the biodiversity and study the secondary metabolites of Antarctic cyanobacteria
peer reviewed The BCCM/ULC public collection is funded by the Belgian Science Policy Office since 2011. A Quality Management System ensures that the services of deposits (both public and safe) and distribution are well documented and efficient for the clients’ satisfaction. It has obtained the ISO 9...
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ftorbi:oai:orbi.ulg.ac.be:2268/213018 2024-04-21T07:46:11+00:00 The BCCM/ULC collection to conserve the biodiversity and study the secondary metabolites of Antarctic cyanobacteria Lara, Yannick Durieu, Benoit Renard, Marine Beets, Kim Stelmach Pessi, Igor Cornet, Luc Simons, Véronique Baurain, Denis Javaux, Emmanuelle Jacques, Philippe Wilmotte, Annick CIP - Centre d'Ingénierie des Protéines - ULiège 2017-06 https://orbi.uliege.be/handle/2268/213018 en eng SCAR https://kuleuvencongres.be/scarbiology2017/articles/bookofabstracts https://orbi.uliege.be/handle/2268/213018 info:hdl:2268/213018 restricted access http://purl.org/coar/access_right/c_16ec info:eu-repo/semantics/restrictedAccess Book of abstracts: XIIth SCAR Biology Symposium, Leuven, Belgium, 10-14 July 2017., 244 (2017-06); XII SCAR Biology Symposium, Leuven, Belgium [BE], 10-14 juillet 2017 cyanobacteria Antarctica culture collection secondary metabolites Life sciences Microbiology Biotechnology Sciences du vivant Microbiologie Biotechnologie conference paper http://purl.org/coar/resource_type/c_5794 info:eu-repo/semantics/conferenceObject peer reviewed 2017 ftorbi 2024-03-27T14:58:25Z peer reviewed The BCCM/ULC public collection is funded by the Belgian Science Policy Office since 2011. A Quality Management System ensures that the services of deposits (both public and safe) and distribution are well documented and efficient for the clients’ satisfaction. It has obtained the ISO 9001 certification for deposition and distribution of strains, as part of the multi-site certification for the BCCM consortium. This collection aims to gather a representative portion of the Antarctic cyanobacterial diversity with different ecological origins (limnetic mats, soil crusts, cryoconites, endoliths…) and make it available for researchers to study the taxonomy, evolution, adaptations to harsh environmental conditions, pigments, and genomic make-up. It presently includes 216 cyanobacterial strains, of which 119 are of Antarctic origin (catalogue: http://bccm.belspo.be/catalogues/ulc-catalogue-search). In addition, cyanobacteria are known to produce a wide range of secondary metabolites (e.g. alkaloids, cyclic and linear peptides, polyketides) with bioactive potential. Genome sequencing of 11 strains has been started to enable genome mining for biosynthetic clusters. Pair-read data from illumina MiSeq runs were obtained and submitted to a bioinformatic pipeline dedicated to the assembly of genomes and search of sequences involved in the biosynthesis of secondary metabolites. Gene cluster prediction analysis allowed to characterize 20 clusters of NRPS, PKS and hybrid NRPS-PKS from 2 to 66kb. Surprisingly, none of the characterized operons had previously been described in the literature. BCCM/ULC, CCAMBIO Conference Object Antarc* Antarctic Antarctica University of Liège: ORBi (Open Repository and Bibliography) |
institution |
Open Polar |
collection |
University of Liège: ORBi (Open Repository and Bibliography) |
op_collection_id |
ftorbi |
language |
English |
topic |
cyanobacteria Antarctica culture collection secondary metabolites Life sciences Microbiology Biotechnology Sciences du vivant Microbiologie Biotechnologie |
spellingShingle |
cyanobacteria Antarctica culture collection secondary metabolites Life sciences Microbiology Biotechnology Sciences du vivant Microbiologie Biotechnologie Lara, Yannick Durieu, Benoit Renard, Marine Beets, Kim Stelmach Pessi, Igor Cornet, Luc Simons, Véronique Baurain, Denis Javaux, Emmanuelle Jacques, Philippe Wilmotte, Annick The BCCM/ULC collection to conserve the biodiversity and study the secondary metabolites of Antarctic cyanobacteria |
topic_facet |
cyanobacteria Antarctica culture collection secondary metabolites Life sciences Microbiology Biotechnology Sciences du vivant Microbiologie Biotechnologie |
description |
peer reviewed The BCCM/ULC public collection is funded by the Belgian Science Policy Office since 2011. A Quality Management System ensures that the services of deposits (both public and safe) and distribution are well documented and efficient for the clients’ satisfaction. It has obtained the ISO 9001 certification for deposition and distribution of strains, as part of the multi-site certification for the BCCM consortium. This collection aims to gather a representative portion of the Antarctic cyanobacterial diversity with different ecological origins (limnetic mats, soil crusts, cryoconites, endoliths…) and make it available for researchers to study the taxonomy, evolution, adaptations to harsh environmental conditions, pigments, and genomic make-up. It presently includes 216 cyanobacterial strains, of which 119 are of Antarctic origin (catalogue: http://bccm.belspo.be/catalogues/ulc-catalogue-search). In addition, cyanobacteria are known to produce a wide range of secondary metabolites (e.g. alkaloids, cyclic and linear peptides, polyketides) with bioactive potential. Genome sequencing of 11 strains has been started to enable genome mining for biosynthetic clusters. Pair-read data from illumina MiSeq runs were obtained and submitted to a bioinformatic pipeline dedicated to the assembly of genomes and search of sequences involved in the biosynthesis of secondary metabolites. Gene cluster prediction analysis allowed to characterize 20 clusters of NRPS, PKS and hybrid NRPS-PKS from 2 to 66kb. Surprisingly, none of the characterized operons had previously been described in the literature. BCCM/ULC, CCAMBIO |
author2 |
CIP - Centre d'Ingénierie des Protéines - ULiège |
format |
Conference Object |
author |
Lara, Yannick Durieu, Benoit Renard, Marine Beets, Kim Stelmach Pessi, Igor Cornet, Luc Simons, Véronique Baurain, Denis Javaux, Emmanuelle Jacques, Philippe Wilmotte, Annick |
author_facet |
Lara, Yannick Durieu, Benoit Renard, Marine Beets, Kim Stelmach Pessi, Igor Cornet, Luc Simons, Véronique Baurain, Denis Javaux, Emmanuelle Jacques, Philippe Wilmotte, Annick |
author_sort |
Lara, Yannick |
title |
The BCCM/ULC collection to conserve the biodiversity and study the secondary metabolites of Antarctic cyanobacteria |
title_short |
The BCCM/ULC collection to conserve the biodiversity and study the secondary metabolites of Antarctic cyanobacteria |
title_full |
The BCCM/ULC collection to conserve the biodiversity and study the secondary metabolites of Antarctic cyanobacteria |
title_fullStr |
The BCCM/ULC collection to conserve the biodiversity and study the secondary metabolites of Antarctic cyanobacteria |
title_full_unstemmed |
The BCCM/ULC collection to conserve the biodiversity and study the secondary metabolites of Antarctic cyanobacteria |
title_sort |
bccm/ulc collection to conserve the biodiversity and study the secondary metabolites of antarctic cyanobacteria |
publisher |
SCAR |
publishDate |
2017 |
url |
https://orbi.uliege.be/handle/2268/213018 |
genre |
Antarc* Antarctic Antarctica |
genre_facet |
Antarc* Antarctic Antarctica |
op_source |
Book of abstracts: XIIth SCAR Biology Symposium, Leuven, Belgium, 10-14 July 2017., 244 (2017-06); XII SCAR Biology Symposium, Leuven, Belgium [BE], 10-14 juillet 2017 |
op_relation |
https://kuleuvencongres.be/scarbiology2017/articles/bookofabstracts https://orbi.uliege.be/handle/2268/213018 info:hdl:2268/213018 |
op_rights |
restricted access http://purl.org/coar/access_right/c_16ec info:eu-repo/semantics/restrictedAccess |
_version_ |
1796942806275588096 |