Is Dolphin Morbillivirus Virulent for White-Beaked Dolphins (Lagenorhynchus albirostris)?
peer reviewed The virulence of morbilliviruses for toothed whales (odontocetes) appears to differ according to host species. In 4 species of odontocetes, morbilliviruses are highly virulent, causing large-scale epizootics with high mortality. In 8 other species of odontocetes, including white-beaked...
Published in: | Veterinary Pathology |
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Format: | Article in Journal/Newspaper |
Language: | English |
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SAGE Publications
2014
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Online Access: | https://orbi.uliege.be/handle/2268/158961 https://orbi.uliege.be/bitstream/2268/158961/1/van%20Elk%202014%20Vet%20Pathol%20online.pdf https://doi.org/10.1177/0300985813516643 |
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ftorbi:oai:orbi.ulg.ac.be:2268/158961 2024-04-21T08:06:40+00:00 Is Dolphin Morbillivirus Virulent for White-Beaked Dolphins (Lagenorhynchus albirostris)? van Elk, C. E. van de Bildt, M. W. G. Jauniaux, Thierry Hiemstra, S. van Run, P. R. W. A. Foster, G. Meerbeek, J. Osterhaus, A. D. M. E. Kuiken, T. 2014 https://orbi.uliege.be/handle/2268/158961 https://orbi.uliege.be/bitstream/2268/158961/1/van%20Elk%202014%20Vet%20Pathol%20online.pdf https://doi.org/10.1177/0300985813516643 en eng SAGE Publications urn:issn:0300-9858 urn:issn:1544-2217 https://orbi.uliege.be/handle/2268/158961 info:hdl:2268/158961 https://orbi.uliege.be/bitstream/2268/158961/1/van%20Elk%202014%20Vet%20Pathol%20online.pdf doi:10.1177/0300985813516643 scopus-id:2-s2.0-84908556070 info:pmid:24399208 open access http://purl.org/coar/access_right/c_abf2 info:eu-repo/semantics/openAccess Veterinary Pathology (2014) Lagenorhynchus albirostris central nervous system clinical signs dolphin immunohistochemistry lungs lymph nodes morbillivirus Life sciences Veterinary medicine & animal health Sciences du vivant Médecine vétérinaire & santé animale journal article http://purl.org/coar/resource_type/c_6501 info:eu-repo/semantics/article peer reviewed 2014 ftorbi https://doi.org/10.1177/0300985813516643 2024-03-27T14:55:45Z peer reviewed The virulence of morbilliviruses for toothed whales (odontocetes) appears to differ according to host species. In 4 species of odontocetes, morbilliviruses are highly virulent, causing large-scale epizootics with high mortality. In 8 other species of odontocetes, including white-beaked dolphins (Lagenorhynchus albirostris), morbilliviruses have been found as an incidental infection. In these species, the virulence of morbilliviruses is not clear. Therefore, the admission of 2 white-beaked dolphins with morbillivirus infection into a rehabilitation center provided a unique opportunity to investigate the virulence of morbillivirus in this species. By phylogenetic analysis, the morbilliviruses in both animals were identified as a dolphin morbillivirus (DMV) most closely related to that detected in a white-beaked dolphin in Germany in 2007. Both animals were examined clinically and pathologically. Case No. 1 had a chronic neural DMV infection, characterized by polioencephalitis in the cerebrum and morbillivirus antigen expression limited to neurons and glial cells. Surprisingly, no nervous signs were observed in this animal during the 6 months before death. Case No. 2 had a subacute systemic DMV infection, characterized by interstitial pneumonia, leucopenia, lymphoid depletion, and DMV antigen expression in mononuclear cells and syncytia in the lung and in mononuclear cells in multiple lymphoid organs. Cause of death was not attributed to DMV infection in either animal. DMV was not detected in 2 contemporaneously stranded white-beaked dolphins. Stranding rate did not increase in the region. These results suggest that DMV is not highly virulent for white-beaked dolphins. Article in Journal/Newspaper Lagenorhynchus albirostris toothed whales White-beaked dolphin University of Liège: ORBi (Open Repository and Bibliography) Veterinary Pathology 51 6 1174 1182 |
institution |
Open Polar |
collection |
University of Liège: ORBi (Open Repository and Bibliography) |
op_collection_id |
ftorbi |
language |
English |
topic |
Lagenorhynchus albirostris central nervous system clinical signs dolphin immunohistochemistry lungs lymph nodes morbillivirus Life sciences Veterinary medicine & animal health Sciences du vivant Médecine vétérinaire & santé animale |
spellingShingle |
Lagenorhynchus albirostris central nervous system clinical signs dolphin immunohistochemistry lungs lymph nodes morbillivirus Life sciences Veterinary medicine & animal health Sciences du vivant Médecine vétérinaire & santé animale van Elk, C. E. van de Bildt, M. W. G. Jauniaux, Thierry Hiemstra, S. van Run, P. R. W. A. Foster, G. Meerbeek, J. Osterhaus, A. D. M. E. Kuiken, T. Is Dolphin Morbillivirus Virulent for White-Beaked Dolphins (Lagenorhynchus albirostris)? |
topic_facet |
Lagenorhynchus albirostris central nervous system clinical signs dolphin immunohistochemistry lungs lymph nodes morbillivirus Life sciences Veterinary medicine & animal health Sciences du vivant Médecine vétérinaire & santé animale |
description |
peer reviewed The virulence of morbilliviruses for toothed whales (odontocetes) appears to differ according to host species. In 4 species of odontocetes, morbilliviruses are highly virulent, causing large-scale epizootics with high mortality. In 8 other species of odontocetes, including white-beaked dolphins (Lagenorhynchus albirostris), morbilliviruses have been found as an incidental infection. In these species, the virulence of morbilliviruses is not clear. Therefore, the admission of 2 white-beaked dolphins with morbillivirus infection into a rehabilitation center provided a unique opportunity to investigate the virulence of morbillivirus in this species. By phylogenetic analysis, the morbilliviruses in both animals were identified as a dolphin morbillivirus (DMV) most closely related to that detected in a white-beaked dolphin in Germany in 2007. Both animals were examined clinically and pathologically. Case No. 1 had a chronic neural DMV infection, characterized by polioencephalitis in the cerebrum and morbillivirus antigen expression limited to neurons and glial cells. Surprisingly, no nervous signs were observed in this animal during the 6 months before death. Case No. 2 had a subacute systemic DMV infection, characterized by interstitial pneumonia, leucopenia, lymphoid depletion, and DMV antigen expression in mononuclear cells and syncytia in the lung and in mononuclear cells in multiple lymphoid organs. Cause of death was not attributed to DMV infection in either animal. DMV was not detected in 2 contemporaneously stranded white-beaked dolphins. Stranding rate did not increase in the region. These results suggest that DMV is not highly virulent for white-beaked dolphins. |
format |
Article in Journal/Newspaper |
author |
van Elk, C. E. van de Bildt, M. W. G. Jauniaux, Thierry Hiemstra, S. van Run, P. R. W. A. Foster, G. Meerbeek, J. Osterhaus, A. D. M. E. Kuiken, T. |
author_facet |
van Elk, C. E. van de Bildt, M. W. G. Jauniaux, Thierry Hiemstra, S. van Run, P. R. W. A. Foster, G. Meerbeek, J. Osterhaus, A. D. M. E. Kuiken, T. |
author_sort |
van Elk, C. E. |
title |
Is Dolphin Morbillivirus Virulent for White-Beaked Dolphins (Lagenorhynchus albirostris)? |
title_short |
Is Dolphin Morbillivirus Virulent for White-Beaked Dolphins (Lagenorhynchus albirostris)? |
title_full |
Is Dolphin Morbillivirus Virulent for White-Beaked Dolphins (Lagenorhynchus albirostris)? |
title_fullStr |
Is Dolphin Morbillivirus Virulent for White-Beaked Dolphins (Lagenorhynchus albirostris)? |
title_full_unstemmed |
Is Dolphin Morbillivirus Virulent for White-Beaked Dolphins (Lagenorhynchus albirostris)? |
title_sort |
is dolphin morbillivirus virulent for white-beaked dolphins (lagenorhynchus albirostris)? |
publisher |
SAGE Publications |
publishDate |
2014 |
url |
https://orbi.uliege.be/handle/2268/158961 https://orbi.uliege.be/bitstream/2268/158961/1/van%20Elk%202014%20Vet%20Pathol%20online.pdf https://doi.org/10.1177/0300985813516643 |
genre |
Lagenorhynchus albirostris toothed whales White-beaked dolphin |
genre_facet |
Lagenorhynchus albirostris toothed whales White-beaked dolphin |
op_source |
Veterinary Pathology (2014) |
op_relation |
urn:issn:0300-9858 urn:issn:1544-2217 https://orbi.uliege.be/handle/2268/158961 info:hdl:2268/158961 https://orbi.uliege.be/bitstream/2268/158961/1/van%20Elk%202014%20Vet%20Pathol%20online.pdf doi:10.1177/0300985813516643 scopus-id:2-s2.0-84908556070 info:pmid:24399208 |
op_rights |
open access http://purl.org/coar/access_right/c_abf2 info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1177/0300985813516643 |
container_title |
Veterinary Pathology |
container_volume |
51 |
container_issue |
6 |
container_start_page |
1174 |
op_container_end_page |
1182 |
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1796946094789230592 |