Incidence of cancer among licenced commercial pilots flying North Atlantic routes
Background: To evaluate cancer incidence among licenced commercial pilots in association with cosmic radiation. Methods: Cohort study where ionizing radiation dose of cosmic radiation was estimated from airline data and software program and cancer incidence was obtained by record linkage with nation...
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Online Access: | https://hdl.handle.net/20.500.11815/445 https://doi.org/10.1186/s12940-017-0295-4 |
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ftopinvisindi:oai:opinvisindi.is:20.500.11815/445 2023-05-15T16:52:11+02:00 Incidence of cancer among licenced commercial pilots flying North Atlantic routes Guðmundsdóttir, Eva María Hrafnkelsson, Jón Rafnsson, Vilhjalmur Læknadeild (HÍ) Faculty of Medicine (UI) Heilbrigðisvísindasvið (HÍ) School of Health Sciences (UI) Háskóli Íslands University of Iceland 2017-08-16 86 https://hdl.handle.net/20.500.11815/445 https://doi.org/10.1186/s12940-017-0295-4 en eng Springer Nature Environmental Health;16(1) http://link.springer.com/content/pdf/10.1186/s12940-017-0295-4.pdf Gudmundsdottir, E. M., Hrafnkelsson, J., & Rafnsson, V. (2017). Incidence of cancer among licenced commercial pilots flying North Atlantic routes. Environmental Health, 16(1), 86. doi:10.1186/s12940-017-0295-4 1476-069X https://hdl.handle.net/20.500.11815/445 Environmental Health doi:10.1186/s12940-017-0295-4 info:eu-repo/semantics/openAccess Malignant melanoma Prostate cancer Cosmic radiation Aircrew Cancer registry Húðkrabbamein Blöðruhálskirtilskrabbamein Geislun Flugmenn info:eu-repo/semantics/article 2017 ftopinvisindi https://doi.org/20.500.11815/445 https://doi.org/10.1186/s12940-017-0295-4 2022-11-18T06:51:33Z Background: To evaluate cancer incidence among licenced commercial pilots in association with cosmic radiation. Methods: Cohort study where ionizing radiation dose of cosmic radiation was estimated from airline data and software program and cancer incidence was obtained by record linkage with nation-wide cancer registry. All licenced commercial male airline pilots were followed from 1955 to 2015, ever or never employed at airline with international routes. Standardized incidence ratios were calculated and relative risk by Poisson regression, to examine exposure-response relation. Results: Eighty three cancers were registered compared with 92 expected; standardized incidence ratios were 0.90 (95% CI 0.71 to 1.11) for all cancers, 3.31 (95% CI 1.33 to 6.81) for malignant melanoma, and 2.49 (95% CI 1.69 to 3.54), for basal cell carcinoma of skin. The risk for all cancers, malignant melanoma, prostate cancer, basal cell carcinoma of skin, and basal cell carcinoma of trunk increased with an increase in number of employment years, cumulative air hours, total cumulative radiation dose, and cumulative radiation dose sustained up to age of 40 years. The relative risk for the highest exposure categories of cumulative radiation dose were 2.42 (95% CI 1.50 to 3.92) for all cancers, 2.57 (95% CI 1.18 to 5.56) for prostate cancer, 9.88 (95% CI 1.57 to 190.78) for malignant melanoma, 3.61 (95% CI 1.64 to 8. 48) for all basal cell carcinoma, and 6.65 (95% CI 1.61 to 44.64) for basal cell carcinoma of trunk. Conclusions: This study was underpowered to study brain cancer and leukaemia risk. Basal cell carcinoma of skin is radiation-related cancer, and may be attributed to cosmic radiation. Further studies are needed to clarify the risk of cancers in association with cosmic radiation, other workplace exposure, host factors, and leisure sun-exposure, as clothes, and glass in cockpit windows shield pilots from the most potent ultraviolet-radiation. University of Iceland Research Fund, grant no. 1238–123414 Peer Reviewed Article in Journal/Newspaper Iceland North Atlantic Opin vísindi (Iceland) Environmental Health 16 1 |
institution |
Open Polar |
collection |
Opin vísindi (Iceland) |
op_collection_id |
ftopinvisindi |
language |
English |
topic |
Malignant melanoma Prostate cancer Cosmic radiation Aircrew Cancer registry Húðkrabbamein Blöðruhálskirtilskrabbamein Geislun Flugmenn |
spellingShingle |
Malignant melanoma Prostate cancer Cosmic radiation Aircrew Cancer registry Húðkrabbamein Blöðruhálskirtilskrabbamein Geislun Flugmenn Guðmundsdóttir, Eva María Hrafnkelsson, Jón Rafnsson, Vilhjalmur Incidence of cancer among licenced commercial pilots flying North Atlantic routes |
topic_facet |
Malignant melanoma Prostate cancer Cosmic radiation Aircrew Cancer registry Húðkrabbamein Blöðruhálskirtilskrabbamein Geislun Flugmenn |
description |
Background: To evaluate cancer incidence among licenced commercial pilots in association with cosmic radiation. Methods: Cohort study where ionizing radiation dose of cosmic radiation was estimated from airline data and software program and cancer incidence was obtained by record linkage with nation-wide cancer registry. All licenced commercial male airline pilots were followed from 1955 to 2015, ever or never employed at airline with international routes. Standardized incidence ratios were calculated and relative risk by Poisson regression, to examine exposure-response relation. Results: Eighty three cancers were registered compared with 92 expected; standardized incidence ratios were 0.90 (95% CI 0.71 to 1.11) for all cancers, 3.31 (95% CI 1.33 to 6.81) for malignant melanoma, and 2.49 (95% CI 1.69 to 3.54), for basal cell carcinoma of skin. The risk for all cancers, malignant melanoma, prostate cancer, basal cell carcinoma of skin, and basal cell carcinoma of trunk increased with an increase in number of employment years, cumulative air hours, total cumulative radiation dose, and cumulative radiation dose sustained up to age of 40 years. The relative risk for the highest exposure categories of cumulative radiation dose were 2.42 (95% CI 1.50 to 3.92) for all cancers, 2.57 (95% CI 1.18 to 5.56) for prostate cancer, 9.88 (95% CI 1.57 to 190.78) for malignant melanoma, 3.61 (95% CI 1.64 to 8. 48) for all basal cell carcinoma, and 6.65 (95% CI 1.61 to 44.64) for basal cell carcinoma of trunk. Conclusions: This study was underpowered to study brain cancer and leukaemia risk. Basal cell carcinoma of skin is radiation-related cancer, and may be attributed to cosmic radiation. Further studies are needed to clarify the risk of cancers in association with cosmic radiation, other workplace exposure, host factors, and leisure sun-exposure, as clothes, and glass in cockpit windows shield pilots from the most potent ultraviolet-radiation. University of Iceland Research Fund, grant no. 1238–123414 Peer Reviewed |
author2 |
Læknadeild (HÍ) Faculty of Medicine (UI) Heilbrigðisvísindasvið (HÍ) School of Health Sciences (UI) Háskóli Íslands University of Iceland |
format |
Article in Journal/Newspaper |
author |
Guðmundsdóttir, Eva María Hrafnkelsson, Jón Rafnsson, Vilhjalmur |
author_facet |
Guðmundsdóttir, Eva María Hrafnkelsson, Jón Rafnsson, Vilhjalmur |
author_sort |
Guðmundsdóttir, Eva María |
title |
Incidence of cancer among licenced commercial pilots flying North Atlantic routes |
title_short |
Incidence of cancer among licenced commercial pilots flying North Atlantic routes |
title_full |
Incidence of cancer among licenced commercial pilots flying North Atlantic routes |
title_fullStr |
Incidence of cancer among licenced commercial pilots flying North Atlantic routes |
title_full_unstemmed |
Incidence of cancer among licenced commercial pilots flying North Atlantic routes |
title_sort |
incidence of cancer among licenced commercial pilots flying north atlantic routes |
publisher |
Springer Nature |
publishDate |
2017 |
url |
https://hdl.handle.net/20.500.11815/445 https://doi.org/10.1186/s12940-017-0295-4 |
genre |
Iceland North Atlantic |
genre_facet |
Iceland North Atlantic |
op_relation |
Environmental Health;16(1) http://link.springer.com/content/pdf/10.1186/s12940-017-0295-4.pdf Gudmundsdottir, E. M., Hrafnkelsson, J., & Rafnsson, V. (2017). Incidence of cancer among licenced commercial pilots flying North Atlantic routes. Environmental Health, 16(1), 86. doi:10.1186/s12940-017-0295-4 1476-069X https://hdl.handle.net/20.500.11815/445 Environmental Health doi:10.1186/s12940-017-0295-4 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/20.500.11815/445 https://doi.org/10.1186/s12940-017-0295-4 |
container_title |
Environmental Health |
container_volume |
16 |
container_issue |
1 |
_version_ |
1766042340137369600 |