Adults with symptoms of pneumonia : a prospective comparison of patients with and without infiltrates on chest radiography
Funding Information: The authors thank the staff at the emergency wards of Landspitali–The National University Hospital of Iceland for assistance with patient recruitment and Salvör Rafnsdóttir for her contribution in terms of patient recruitment. Funding Information: This work was supported by The...
Published in: | Clinical Microbiology and Infection |
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Online Access: | https://hdl.handle.net/20.500.11815/4385 https://doi.org/10.1016/j.cmi.2022.07.013 |
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ftopinvisindi:oai:opinvisindi.is:20.500.11815/4385 2024-02-04T10:01:26+01:00 Adults with symptoms of pneumonia : a prospective comparison of patients with and without infiltrates on chest radiography Rögnvaldsson, Kristján Godsk Bjarnason, Agnar Ólafsdóttir, Inga Sif Helgason, Kristján Orri Guðmundsson, Aðalsteinn Gottfreðsson, Magnús Faculty of Medicine Other departments University of Iceland 2023-01 503203 108.e1-108.e6 https://hdl.handle.net/20.500.11815/4385 https://doi.org/10.1016/j.cmi.2022.07.013 en eng Clinical Microbiology and Infection; 29(1) http://www.scopus.com/inward/record.url?scp=85137627325&partnerID=8YFLogxK Rögnvaldsson , K G , Bjarnason , A , Ólafsdóttir , I S , Helgason , K O , Guðmundsson , A & Gottfreðsson , M 2023 , ' Adults with symptoms of pneumonia : a prospective comparison of patients with and without infiltrates on chest radiography ' , Clinical Microbiology and Infection , vol. 29 , no. 1 , pp. 108.e1-108.e6 . https://doi.org/10.1016/j.cmi.2022.07.013 1198-743X 66611787 0453e4eb-5c0b-469b-92a7-d049e19de90d 85137627325 35872174 unpaywall: 10.1016/j.cmi.2022.07.013 https://hdl.handle.net/20.500.11815/4385 doi:10.1016/j.cmi.2022.07.013 info:eu-repo/semantics/openAccess Smitsjúkdómalæknisfræði Lungnalæknisfræði Öldrunarlæknisfræði Chest x-ray Community-acquired pneumonia Lower respiratory tract infections Population-based Prospective-study Humans Male Viruses Community-Acquired Infections/diagnostic imaging Hospitalization Streptococcus pneumoniae Radiography Adult Female Aged Pneumonia/diagnostic imaging Microbiology (medical) Infectious Diseases /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article 2023 ftopinvisindi https://doi.org/20.500.11815/438510.1016/j.cmi.2022.07.013 2024-01-10T23:55:20Z Funding Information: The authors thank the staff at the emergency wards of Landspitali–The National University Hospital of Iceland for assistance with patient recruitment and Salvör Rafnsdóttir for her contribution in terms of patient recruitment. Funding Information: This work was supported by The Icelandic Centre for Research (Rannís) (grant number 217716-051), The Doctoral Grants of The University of Iceland Research Fund, The Scientific fund of Landspitali- The National University Hospital of Iceland, The Scandinavian Society for Antimicrobial Chemotherapy Foundation, and the Foundation of St. Josef's Hospital. The funding sources had no role in the study's design, conduct or reporting. Publisher Copyright: © 2022 The Author(s) OBJECTIVE: Most studies on patients hospitalized with community-acquired pneumonia (CAP) require confirmation of an infiltrate by chest radiography, but in practice admissions are common among patients with symptoms of pneumonia without an infiltrate (SPWI). The aim of this research was to compare clinical characteristics, microbial etiology, and outcomes among patients with CAP and SPWI. METHODS: Adults suspected of CAP were prospectively recruited at Landspitali University Hospital over a 1-year period, 2018 to 2019. The study was population based. Those admitted with two or more of the following symptoms were invited to participate: temperature ≥38°C or ≤36°C, sweating, shaking/chills, chest pain, a new cough, or new onset of dyspnea. Primary outcome was mortality at 30 days and one year. RESULTS: Six hundred twenty-five cases were included, 409 with CAP and 216 with SPWI; median age was 75 (interquartile range [IQR] 64-84) and 315 (50.4%) were females. Patients with CAP were more likely to have fever (≥38.0°C) (66.9% [273/408]) vs. 49.3% (106/215), p < 0.001), a higher CRP (median 103 [IQR 34-205] vs. 55 (IQR 17-103), p < 0.001), identification of Streptococcus pneumoniae (18.0% [64/355]) vs. 6.3% (10/159) of tested, p = 0.002) and to receive antibacterial treatment (99.5% ... Article in Journal/Newspaper Iceland Opin vísindi (Iceland) Clinical Microbiology and Infection 29 1 108.e1 108.e6 |
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Opin vísindi (Iceland) |
op_collection_id |
ftopinvisindi |
language |
English |
topic |
Smitsjúkdómalæknisfræði Lungnalæknisfræði Öldrunarlæknisfræði Chest x-ray Community-acquired pneumonia Lower respiratory tract infections Population-based Prospective-study Humans Male Viruses Community-Acquired Infections/diagnostic imaging Hospitalization Streptococcus pneumoniae Radiography Adult Female Aged Pneumonia/diagnostic imaging Microbiology (medical) Infectious Diseases |
spellingShingle |
Smitsjúkdómalæknisfræði Lungnalæknisfræði Öldrunarlæknisfræði Chest x-ray Community-acquired pneumonia Lower respiratory tract infections Population-based Prospective-study Humans Male Viruses Community-Acquired Infections/diagnostic imaging Hospitalization Streptococcus pneumoniae Radiography Adult Female Aged Pneumonia/diagnostic imaging Microbiology (medical) Infectious Diseases Rögnvaldsson, Kristján Godsk Bjarnason, Agnar Ólafsdóttir, Inga Sif Helgason, Kristján Orri Guðmundsson, Aðalsteinn Gottfreðsson, Magnús Adults with symptoms of pneumonia : a prospective comparison of patients with and without infiltrates on chest radiography |
topic_facet |
Smitsjúkdómalæknisfræði Lungnalæknisfræði Öldrunarlæknisfræði Chest x-ray Community-acquired pneumonia Lower respiratory tract infections Population-based Prospective-study Humans Male Viruses Community-Acquired Infections/diagnostic imaging Hospitalization Streptococcus pneumoniae Radiography Adult Female Aged Pneumonia/diagnostic imaging Microbiology (medical) Infectious Diseases |
description |
Funding Information: The authors thank the staff at the emergency wards of Landspitali–The National University Hospital of Iceland for assistance with patient recruitment and Salvör Rafnsdóttir for her contribution in terms of patient recruitment. Funding Information: This work was supported by The Icelandic Centre for Research (Rannís) (grant number 217716-051), The Doctoral Grants of The University of Iceland Research Fund, The Scientific fund of Landspitali- The National University Hospital of Iceland, The Scandinavian Society for Antimicrobial Chemotherapy Foundation, and the Foundation of St. Josef's Hospital. The funding sources had no role in the study's design, conduct or reporting. Publisher Copyright: © 2022 The Author(s) OBJECTIVE: Most studies on patients hospitalized with community-acquired pneumonia (CAP) require confirmation of an infiltrate by chest radiography, but in practice admissions are common among patients with symptoms of pneumonia without an infiltrate (SPWI). The aim of this research was to compare clinical characteristics, microbial etiology, and outcomes among patients with CAP and SPWI. METHODS: Adults suspected of CAP were prospectively recruited at Landspitali University Hospital over a 1-year period, 2018 to 2019. The study was population based. Those admitted with two or more of the following symptoms were invited to participate: temperature ≥38°C or ≤36°C, sweating, shaking/chills, chest pain, a new cough, or new onset of dyspnea. Primary outcome was mortality at 30 days and one year. RESULTS: Six hundred twenty-five cases were included, 409 with CAP and 216 with SPWI; median age was 75 (interquartile range [IQR] 64-84) and 315 (50.4%) were females. Patients with CAP were more likely to have fever (≥38.0°C) (66.9% [273/408]) vs. 49.3% (106/215), p < 0.001), a higher CRP (median 103 [IQR 34-205] vs. 55 (IQR 17-103), p < 0.001), identification of Streptococcus pneumoniae (18.0% [64/355]) vs. 6.3% (10/159) of tested, p = 0.002) and to receive antibacterial treatment (99.5% ... |
author2 |
Faculty of Medicine Other departments University of Iceland |
format |
Article in Journal/Newspaper |
author |
Rögnvaldsson, Kristján Godsk Bjarnason, Agnar Ólafsdóttir, Inga Sif Helgason, Kristján Orri Guðmundsson, Aðalsteinn Gottfreðsson, Magnús |
author_facet |
Rögnvaldsson, Kristján Godsk Bjarnason, Agnar Ólafsdóttir, Inga Sif Helgason, Kristján Orri Guðmundsson, Aðalsteinn Gottfreðsson, Magnús |
author_sort |
Rögnvaldsson, Kristján Godsk |
title |
Adults with symptoms of pneumonia : a prospective comparison of patients with and without infiltrates on chest radiography |
title_short |
Adults with symptoms of pneumonia : a prospective comparison of patients with and without infiltrates on chest radiography |
title_full |
Adults with symptoms of pneumonia : a prospective comparison of patients with and without infiltrates on chest radiography |
title_fullStr |
Adults with symptoms of pneumonia : a prospective comparison of patients with and without infiltrates on chest radiography |
title_full_unstemmed |
Adults with symptoms of pneumonia : a prospective comparison of patients with and without infiltrates on chest radiography |
title_sort |
adults with symptoms of pneumonia : a prospective comparison of patients with and without infiltrates on chest radiography |
publishDate |
2023 |
url |
https://hdl.handle.net/20.500.11815/4385 https://doi.org/10.1016/j.cmi.2022.07.013 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
Clinical Microbiology and Infection; 29(1) http://www.scopus.com/inward/record.url?scp=85137627325&partnerID=8YFLogxK Rögnvaldsson , K G , Bjarnason , A , Ólafsdóttir , I S , Helgason , K O , Guðmundsson , A & Gottfreðsson , M 2023 , ' Adults with symptoms of pneumonia : a prospective comparison of patients with and without infiltrates on chest radiography ' , Clinical Microbiology and Infection , vol. 29 , no. 1 , pp. 108.e1-108.e6 . https://doi.org/10.1016/j.cmi.2022.07.013 1198-743X 66611787 0453e4eb-5c0b-469b-92a7-d049e19de90d 85137627325 35872174 unpaywall: 10.1016/j.cmi.2022.07.013 https://hdl.handle.net/20.500.11815/4385 doi:10.1016/j.cmi.2022.07.013 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/20.500.11815/438510.1016/j.cmi.2022.07.013 |
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Clinical Microbiology and Infection |
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29 |
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108.e1 |
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108.e6 |
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