Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo)
Purpose To describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having undergone antireflux surgery with those who have not regarding risk of cancers,...
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Online Access: | https://hdl.handle.net/20.500.11815/427 https://doi.org/10.1136/bmjopen-2017-016505 |
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ftopinvisindi:oai:opinvisindi.is:20.500.11815/427 2024-09-15T18:14:20+00:00 Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo) Maret-Ouda, John Wahlin, Karl Artama, Miia Brusselaers, Nele Färkkilä, Martti Lynge, Elsebeth Mattsson, Fredrik Pukkala, Eero Romundstad, Pål Tryggvadottir, Laufey Euler-Chelpin, My von Lagergren, Jesper Faculty of Medicine (UI) Læknadeild (HÍ) Heilbrigðisvísindasvið (HÍ) School of Health Sciences (UI) Háskóli Íslands University of Iceland 2017-06 e016505 https://hdl.handle.net/20.500.11815/427 https://doi.org/10.1136/bmjopen-2017-016505 en eng BMJ BMJ Open;7(6) https://syndication.highwire.org/content/doi/10.1136/bmjopen-2017-016505 Maret-Ouda, J., Wahlin, K., Artama, M., Brusselaers, N., Färkkilä, M., Lynge, E., . . . Lagergren, J. (2017). Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo). BMJ Open, 7(6). doi:10.1136/bmjopen-2017-016505 2044-6055 https://hdl.handle.net/20.500.11815/427 BMJ Open doi:10.1136/bmjopen-2017-016505 info:eu-repo/semantics/openAccess Meltingarfærasjúkdómar Krabbamein info:eu-repo/semantics/article 2017 ftopinvisindi https://doi.org/20.500.11815/42710.1136/bmjopen-2017-016505 2024-07-09T03:01:56Z Purpose To describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having undergone antireflux surgery with those who have not regarding risk of cancers, other diseases and mortality. Participants Included were individuals with a GORD diagnosis recorded in any of the nationwide patient registries in the Nordic countries (Denmark, Finland, Iceland, Norway and Sweden) in 1964–2014 (with various start and end years in different countries). Data regarding cancer, other diseases and mortality were retrieved from the nationwide registries for cancer, patients and causes of death, respectively. Findings to date The NordASCo includes 945 153 individuals with a diagnosis of GORD. Of these, 48 433 (5.1%) have undergone primary antireflux surgery. Median age at primary antireflux surgery ranged from 47 to 52 years in the different countries. The coding practices of GORD seem to have differed between the Nordic countries. Future plans The NordASCo will initially be used to analyse the risk of developing known or potential GORD-related cancers, that is, tumours of the oesophagus, stomach, larynx, pharynx and lung, and to evaluate the mortality in the short-term and long-term perspectives. Additionally, the cohort will be used to evaluate the risk of non-malignant respiratory conditions that might be caused by aspiration of gastric contents. This work was supported by the Swedish Research Council [D0547801], the Swedish Cancer Society [2015/460] and the Nordic Cancer Union [186058]. The grant providers had no role in the design, conduction, analysis or reporting of the cohort. Peer Reviewed Article in Journal/Newspaper Iceland Opin vísindi (Iceland) BMJ Open 7 6 e016505 |
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Opin vísindi (Iceland) |
op_collection_id |
ftopinvisindi |
language |
English |
topic |
Meltingarfærasjúkdómar Krabbamein |
spellingShingle |
Meltingarfærasjúkdómar Krabbamein Maret-Ouda, John Wahlin, Karl Artama, Miia Brusselaers, Nele Färkkilä, Martti Lynge, Elsebeth Mattsson, Fredrik Pukkala, Eero Romundstad, Pål Tryggvadottir, Laufey Euler-Chelpin, My von Lagergren, Jesper Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo) |
topic_facet |
Meltingarfærasjúkdómar Krabbamein |
description |
Purpose To describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having undergone antireflux surgery with those who have not regarding risk of cancers, other diseases and mortality. Participants Included were individuals with a GORD diagnosis recorded in any of the nationwide patient registries in the Nordic countries (Denmark, Finland, Iceland, Norway and Sweden) in 1964–2014 (with various start and end years in different countries). Data regarding cancer, other diseases and mortality were retrieved from the nationwide registries for cancer, patients and causes of death, respectively. Findings to date The NordASCo includes 945 153 individuals with a diagnosis of GORD. Of these, 48 433 (5.1%) have undergone primary antireflux surgery. Median age at primary antireflux surgery ranged from 47 to 52 years in the different countries. The coding practices of GORD seem to have differed between the Nordic countries. Future plans The NordASCo will initially be used to analyse the risk of developing known or potential GORD-related cancers, that is, tumours of the oesophagus, stomach, larynx, pharynx and lung, and to evaluate the mortality in the short-term and long-term perspectives. Additionally, the cohort will be used to evaluate the risk of non-malignant respiratory conditions that might be caused by aspiration of gastric contents. This work was supported by the Swedish Research Council [D0547801], the Swedish Cancer Society [2015/460] and the Nordic Cancer Union [186058]. The grant providers had no role in the design, conduction, analysis or reporting of the cohort. Peer Reviewed |
author2 |
Faculty of Medicine (UI) Læknadeild (HÍ) Heilbrigðisvísindasvið (HÍ) School of Health Sciences (UI) Háskóli Íslands University of Iceland |
format |
Article in Journal/Newspaper |
author |
Maret-Ouda, John Wahlin, Karl Artama, Miia Brusselaers, Nele Färkkilä, Martti Lynge, Elsebeth Mattsson, Fredrik Pukkala, Eero Romundstad, Pål Tryggvadottir, Laufey Euler-Chelpin, My von Lagergren, Jesper |
author_facet |
Maret-Ouda, John Wahlin, Karl Artama, Miia Brusselaers, Nele Färkkilä, Martti Lynge, Elsebeth Mattsson, Fredrik Pukkala, Eero Romundstad, Pål Tryggvadottir, Laufey Euler-Chelpin, My von Lagergren, Jesper |
author_sort |
Maret-Ouda, John |
title |
Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo) |
title_short |
Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo) |
title_full |
Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo) |
title_fullStr |
Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo) |
title_full_unstemmed |
Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo) |
title_sort |
cohort profile: the nordic antireflux surgery cohort (nordasco) |
publisher |
BMJ |
publishDate |
2017 |
url |
https://hdl.handle.net/20.500.11815/427 https://doi.org/10.1136/bmjopen-2017-016505 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
BMJ Open;7(6) https://syndication.highwire.org/content/doi/10.1136/bmjopen-2017-016505 Maret-Ouda, J., Wahlin, K., Artama, M., Brusselaers, N., Färkkilä, M., Lynge, E., . . . Lagergren, J. (2017). Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo). BMJ Open, 7(6). doi:10.1136/bmjopen-2017-016505 2044-6055 https://hdl.handle.net/20.500.11815/427 BMJ Open doi:10.1136/bmjopen-2017-016505 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/20.500.11815/42710.1136/bmjopen-2017-016505 |
container_title |
BMJ Open |
container_volume |
7 |
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6 |
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e016505 |
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1810452096048168960 |