Contaminated dicloxacillin capsules as the source of an NDM-5/OXA-48-producing Enterobacter hormaechei ST79 outbreak, Denmark and Iceland, 2022 and 2023

• Published in: Eurosurveillance
• Main Authors: Agergaard, Charlotte Nielsen, Porsbo, Lone Jannok, Sydenham, Thomas Vognbjerg, Hansen, Sanne Grønvall Kjær, Steinke, Kat, Larsen, Sanne Løkkegaard, Helgason, Kristján Orri, Hansen, Frank, Karstensen, Kasper Thystrup, Henius, Anna E, Holzknecht, Barbara Juliane, Søes, Lillian, Schønning, Kristian, Wang, Mikala, Ank, Nina, Halldórsdóttir, Anna Margrét, Guðlaugsson, Ólafur, Hammerum, Anette M, Kjerulf, Anne, Kristensen, Brian, Hasman, Henrik, Justesen, Ulrik Stenz
• Other Authors: Other departments
• Format: Article in Journal/Newspaper
• Language: English
• Published: 2023
• Subjects: Sýklafræði; Smitsjúkdómalæknisfræði; Humans; Iceland/epidemiology; Dicloxacillin; Disease Outbreaks; Denmark/epidemiology; Public Health; Environmental and Occupational Health; Epidemiology; Virology; Iceland
• Online Access: https://hdl.handle.net/20.500.11815/4162; https://doi.org/10.2807/1560-7917.ES.2023.28.9.2300108

Publisher Copyright: © 2023 European Centre for Disease Prevention and Control (ECDC). All rights reserved. From October 2022 through January 2023, nine patients with NDM-5/OXA-48-carbapenemase-producing Enterobacter hormaechei ST79 were detected in Denmark and subsequently one patient in Iceland. There were no nosocomial links between patients, but they had all been treated with dicloxacillin capsules. An NDM-5/OXA-48-carbapenemase-producing E. hormaechei ST79, identical to patient isolates, was cultured from the surface of dicloxacillin capsules in Denmark, strongly implicating them as the source of the outbreak. Special attention is required to detect the outbreak strain in the microbiology laboratory. Peer reviewed