In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden
Funding We thank the Icelandic Cancer Society, the Icelandic Oncologists Research fund and Göngum Saman, a nonprofit organization, for financial support. Publisher Copyright: © 2020, The Author(s). The purpose was to review the incidence of in situ carcinoma in Iceland after initiating population-ba...
Published in: | Scientific Reports |
---|---|
Main Authors: | , , , , , , , , |
Other Authors: | , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
2020
|
Subjects: | |
Online Access: | https://hdl.handle.net/20.500.11815/3431 https://doi.org/10.1038/s41598-020-74134-5 |
id |
ftopinvisindi:oai:opinvisindi.is:20.500.11815/3431 |
---|---|
record_format |
openpolar |
spelling |
ftopinvisindi:oai:opinvisindi.is:20.500.11815/3431 2023-11-12T04:18:56+01:00 In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden Agustsson, Arnar S. Birgisson, Helgi Agnarsson, Bjarni A. Jonsson, Thorvaldur Stefansdottir, Hrefna Wärnberg, Fredrik Lambe, Mats Tryggvadottir, Laufey Sverrisdottir, Asgerdur Perioperative Services Faculty of Medicine Clinical Laboratory Services, Diagnostics and Blood Bank 2020-12-01 1060083 https://hdl.handle.net/20.500.11815/3431 https://doi.org/10.1038/s41598-020-74134-5 en eng Scientific Reports; 10(1) http://www.scopus.com/inward/record.url?scp=85092767556&partnerID=8YFLogxK Agustsson , A S , Birgisson , H , Agnarsson , B A , Jonsson , T , Stefansdottir , H , Wärnberg , F , Lambe , M , Tryggvadottir , L & Sverrisdottir , A 2020 , ' In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden ' , Scientific Reports , vol. 10 , no. 1 , 17623 . https://doi.org/10.1038/s41598-020-74134-5 2045-2322 42637070 96ebd56e-969c-44a4-b591-f0b917cc4949 85092767556 33077767 https://hdl.handle.net/20.500.11815/3431 doi:10.1038/s41598-020-74134-5 info:eu-repo/semantics/openAccess Multidisciplinary /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article 2020 ftopinvisindi https://doi.org/20.500.11815/343110.1038/s41598-020-74134-5 2023-11-01T23:55:22Z Funding We thank the Icelandic Cancer Society, the Icelandic Oncologists Research fund and Göngum Saman, a nonprofit organization, for financial support. Publisher Copyright: © 2020, The Author(s). The purpose was to review the incidence of in situ carcinoma in Iceland after initiating population-based mammography screening in 1987 and to compare management of ductal carcinoma in situ (DCIS) between Iceland and the Uppsala–Örebro region (UÖR) in Central Sweden. The Icelandic Cancer Registry provided data on in situ breast carcinomas for women between 1957 and 2017. Clinical data for women with DCIS between 2008 and 2014 was extracted from hospital records and compared to women diagnosed in UÖR. In Iceland, in situ carcinoma incidence increased from 7 to 30 per 100 000 women per year, following the introduction of organised mammography screening. The proportion of in situ carcinoma of all breast carcinomas increased from 4 to 12%. More than one third (35%) of women diagnosed with DCIS in Iceland were older than 70 years versus 18% in UÖR. In Iceland, 49% of all DCIS women underwent mastectomy compared to 40% in UÖR. The incidence of in situ carcinoma in Iceland increased four-fold after the uptake of population-based mammography screening causing considerable risk of overtreatment. Differences in treatment of DCIS were seen between Iceland and UÖR, revealing the importance of quality registration for monitoring patterns of management. Peer reviewed Article in Journal/Newspaper Iceland Opin vísindi (Iceland) Scientific Reports 10 1 |
institution |
Open Polar |
collection |
Opin vísindi (Iceland) |
op_collection_id |
ftopinvisindi |
language |
English |
topic |
Multidisciplinary |
spellingShingle |
Multidisciplinary Agustsson, Arnar S. Birgisson, Helgi Agnarsson, Bjarni A. Jonsson, Thorvaldur Stefansdottir, Hrefna Wärnberg, Fredrik Lambe, Mats Tryggvadottir, Laufey Sverrisdottir, Asgerdur In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
topic_facet |
Multidisciplinary |
description |
Funding We thank the Icelandic Cancer Society, the Icelandic Oncologists Research fund and Göngum Saman, a nonprofit organization, for financial support. Publisher Copyright: © 2020, The Author(s). The purpose was to review the incidence of in situ carcinoma in Iceland after initiating population-based mammography screening in 1987 and to compare management of ductal carcinoma in situ (DCIS) between Iceland and the Uppsala–Örebro region (UÖR) in Central Sweden. The Icelandic Cancer Registry provided data on in situ breast carcinomas for women between 1957 and 2017. Clinical data for women with DCIS between 2008 and 2014 was extracted from hospital records and compared to women diagnosed in UÖR. In Iceland, in situ carcinoma incidence increased from 7 to 30 per 100 000 women per year, following the introduction of organised mammography screening. The proportion of in situ carcinoma of all breast carcinomas increased from 4 to 12%. More than one third (35%) of women diagnosed with DCIS in Iceland were older than 70 years versus 18% in UÖR. In Iceland, 49% of all DCIS women underwent mastectomy compared to 40% in UÖR. The incidence of in situ carcinoma in Iceland increased four-fold after the uptake of population-based mammography screening causing considerable risk of overtreatment. Differences in treatment of DCIS were seen between Iceland and UÖR, revealing the importance of quality registration for monitoring patterns of management. Peer reviewed |
author2 |
Perioperative Services Faculty of Medicine Clinical Laboratory Services, Diagnostics and Blood Bank |
format |
Article in Journal/Newspaper |
author |
Agustsson, Arnar S. Birgisson, Helgi Agnarsson, Bjarni A. Jonsson, Thorvaldur Stefansdottir, Hrefna Wärnberg, Fredrik Lambe, Mats Tryggvadottir, Laufey Sverrisdottir, Asgerdur |
author_facet |
Agustsson, Arnar S. Birgisson, Helgi Agnarsson, Bjarni A. Jonsson, Thorvaldur Stefansdottir, Hrefna Wärnberg, Fredrik Lambe, Mats Tryggvadottir, Laufey Sverrisdottir, Asgerdur |
author_sort |
Agustsson, Arnar S. |
title |
In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
title_short |
In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
title_full |
In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
title_fullStr |
In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
title_full_unstemmed |
In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden |
title_sort |
in situ breast cancer incidence patterns in iceland and differences in ductal carcinoma in situ treatment compared to sweden |
publishDate |
2020 |
url |
https://hdl.handle.net/20.500.11815/3431 https://doi.org/10.1038/s41598-020-74134-5 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
Scientific Reports; 10(1) http://www.scopus.com/inward/record.url?scp=85092767556&partnerID=8YFLogxK Agustsson , A S , Birgisson , H , Agnarsson , B A , Jonsson , T , Stefansdottir , H , Wärnberg , F , Lambe , M , Tryggvadottir , L & Sverrisdottir , A 2020 , ' In situ breast cancer incidence patterns in Iceland and differences in ductal carcinoma in situ treatment compared to Sweden ' , Scientific Reports , vol. 10 , no. 1 , 17623 . https://doi.org/10.1038/s41598-020-74134-5 2045-2322 42637070 96ebd56e-969c-44a4-b591-f0b917cc4949 85092767556 33077767 https://hdl.handle.net/20.500.11815/3431 doi:10.1038/s41598-020-74134-5 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/20.500.11815/343110.1038/s41598-020-74134-5 |
container_title |
Scientific Reports |
container_volume |
10 |
container_issue |
1 |
_version_ |
1782335452757360640 |