Post-translational protein deimination in cod (Gadus morhua L.) ontogeny novel roles in tissue remodelling and mucosal immune defences?

• Published in: Developmental & Comparative Immunology
• Main Authors: Magnadottir, Bergljot, Hayes, Polly, Hristova, Mariya, Bragason, Birkir, Nicholas, Anthony P., Dodds, Alister W., Guðmundsdóttir, Sigríður, Lange, Sigrun
• Other Authors: Tilraunastöð í meinafræði að Keldum (HÍ), Institute for Experimental Pathology, Keldur (UI), Háskóli Íslands (HÍ), University of Iceland (UI)
• Format: Article in Journal/Newspaper
• Language: English
• Published: Elsevier BV 2018
• Subjects: Peptidylarginine deiminase; Protein deimination; Mucosal immunity; Central nervous system; Cod; Ontogeny; Þorskur; Taugakerfi; Þroskunarfræði; Ónæmisfræði; Ensím; Grindavík; Staður; Gadus morhua; Iceland
• Online Access: https://hdl.handle.net/20.500.11815/1433; https://doi.org/10.1016/j.dci.2018.06.006

Publisher's version (útgefin grein). Peptidylarginine deiminases (PADs) are calcium dependent enzymes with physiological and pathophysiologicalroles conserved throughout phylogeny. PADs promote post-translational deimination of protein arginine to ci-trulline, altering the structure and functio...