The Atlantic salmon interleukin 4/13 receptor family: Structure, tissue distribution and modulation of gene expression

• Published in: Fish & Shellfish Immunology
• Main Authors: Sequeida, Alvaro, Castillo, Andrés, Cordero, Natalia, Wong, Valentina, Montero, Ruth, Vergara, Claudio, Valenzuela, Beatriz, Vargas, Deborah, Valdés, Natalia, Morales, Jonathan, Tello, Mario, Sandino, Ana María, Maisey, Kevin, Imarai, Mónica
• Format: Article in Journal/Newspaper
• Language: English
• Published: Elsevier BV 2019
• Subjects: Text; ddc:570; IL-4/13 receptors > In silico protein structure > IL-4/13A > Atlantic salmon; Gata; Atlantic salmon
• Online Access: https://doi.org/10.1016/j.fsi.2019.11.030; https://www.openagrar.de/receive/openagrar_mods_00052739; https://www.openagrar.de/servlets/MCRFileNodeServlet/openagrar_derivate_00027736/SD2019440_SD202091.pdf; https://www.sciencedirect.com/science/article/abs/pii/S1050464819310733

Interleukin (IL)-4 and IL-13 play a central role in T helper 2 immune response in mammals. The cell signalling is mediated by the type I heterodimeric receptor containing the IL-4Rα and γC chains, and the type II receptors formed by IL-4Rα and IL-13Rα1. In salmonid species, three paralogues of the I...