Sequences of the Botulinal Neurotoxin-e Derived from Clostridium-Botulinum Type-e (Strain-Beluga) and Clostridium-Butyricum (Strains Atcc-43181 and Atcc-43755)
Recently, it has been shown that two Clostridium butyricum strains (ATCC 43181 and ATCC 43755), isolated from cases of infant botulism, produce a botulinal neurotoxin type E (BoNT/E). Here we have determined the nucleotide sequences of the BoNT/E genes of these two C. butyricum strains and from C. b...
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ftopenagrar:oai:www.openagrar.de:openagrar_mods_00038982 2023-05-15T15:41:41+02:00 Sequences of the Botulinal Neurotoxin-e Derived from Clostridium-Botulinum Type-e (Strain-Beluga) and Clostridium-Butyricum (Strains Atcc-43181 and Atcc-43755) Poulet, S. Hauser, D. Quanz, M. Niemann, Heiner Popoff, M. R. 1992 https://www.openagrar.de/receive/openagrar_mods_00038982 https://www.openagrar.de/servlets/MCRFileNodeServlet/openagrar_derivate_00013044/SD19925.pdf eng eng Biochemical and biophysical research communications -- BBRC; BBRCA9; Biochem Biophys Res Commun -- 0006-291X -- 205723-2 -- 1461396-7 -- http://www.sciencedirect.com/science/journal/0006291X -- http://www.bibliothek.uni-regensburg.de/ezeit/?1461396 https://www.openagrar.de/receive/openagrar_mods_00038982 https://www.openagrar.de/servlets/MCRFileNodeServlet/openagrar_derivate_00013044/SD19925.pdf only signed in user all rights reserved info:eu-repo/semantics/openAccess Text ddc:610 article Text 1992 ftopenagrar 2023-03-06T00:11:45Z Recently, it has been shown that two Clostridium butyricum strains (ATCC 43181 and ATCC 43755), isolated from cases of infant botulism, produce a botulinal neurotoxin type E (BoNT/E). Here we have determined the nucleotide sequences of the BoNT/E genes of these two C. butyricum strains and from C. botulinum E strain Beluga. We show that the sequences of the BoNT/E genes from the two C. butyricum strains are identical and differ in only 64 positions resulting in 39 amino acid changes (97% identity at the amino acid level) from that derived from C. botulinum. Our data suggest a transfer of the BoNT/E gene from C. botulinum to the originally nontoxigenic C. butyricum strains. Article in Journal/Newspaper Beluga Beluga* OpenAgrar (OA) |
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topic |
Text ddc:610 |
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Text ddc:610 Poulet, S. Hauser, D. Quanz, M. Niemann, Heiner Popoff, M. R. Sequences of the Botulinal Neurotoxin-e Derived from Clostridium-Botulinum Type-e (Strain-Beluga) and Clostridium-Butyricum (Strains Atcc-43181 and Atcc-43755) |
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Text ddc:610 |
description |
Recently, it has been shown that two Clostridium butyricum strains (ATCC 43181 and ATCC 43755), isolated from cases of infant botulism, produce a botulinal neurotoxin type E (BoNT/E). Here we have determined the nucleotide sequences of the BoNT/E genes of these two C. butyricum strains and from C. botulinum E strain Beluga. We show that the sequences of the BoNT/E genes from the two C. butyricum strains are identical and differ in only 64 positions resulting in 39 amino acid changes (97% identity at the amino acid level) from that derived from C. botulinum. Our data suggest a transfer of the BoNT/E gene from C. botulinum to the originally nontoxigenic C. butyricum strains. |
format |
Article in Journal/Newspaper |
author |
Poulet, S. Hauser, D. Quanz, M. Niemann, Heiner Popoff, M. R. |
author_facet |
Poulet, S. Hauser, D. Quanz, M. Niemann, Heiner Popoff, M. R. |
author_sort |
Poulet, S. |
title |
Sequences of the Botulinal Neurotoxin-e Derived from Clostridium-Botulinum Type-e (Strain-Beluga) and Clostridium-Butyricum (Strains Atcc-43181 and Atcc-43755) |
title_short |
Sequences of the Botulinal Neurotoxin-e Derived from Clostridium-Botulinum Type-e (Strain-Beluga) and Clostridium-Butyricum (Strains Atcc-43181 and Atcc-43755) |
title_full |
Sequences of the Botulinal Neurotoxin-e Derived from Clostridium-Botulinum Type-e (Strain-Beluga) and Clostridium-Butyricum (Strains Atcc-43181 and Atcc-43755) |
title_fullStr |
Sequences of the Botulinal Neurotoxin-e Derived from Clostridium-Botulinum Type-e (Strain-Beluga) and Clostridium-Butyricum (Strains Atcc-43181 and Atcc-43755) |
title_full_unstemmed |
Sequences of the Botulinal Neurotoxin-e Derived from Clostridium-Botulinum Type-e (Strain-Beluga) and Clostridium-Butyricum (Strains Atcc-43181 and Atcc-43755) |
title_sort |
sequences of the botulinal neurotoxin-e derived from clostridium-botulinum type-e (strain-beluga) and clostridium-butyricum (strains atcc-43181 and atcc-43755) |
publishDate |
1992 |
url |
https://www.openagrar.de/receive/openagrar_mods_00038982 https://www.openagrar.de/servlets/MCRFileNodeServlet/openagrar_derivate_00013044/SD19925.pdf |
genre |
Beluga Beluga* |
genre_facet |
Beluga Beluga* |
op_relation |
Biochemical and biophysical research communications -- BBRC; BBRCA9; Biochem Biophys Res Commun -- 0006-291X -- 205723-2 -- 1461396-7 -- http://www.sciencedirect.com/science/journal/0006291X -- http://www.bibliothek.uni-regensburg.de/ezeit/?1461396 https://www.openagrar.de/receive/openagrar_mods_00038982 https://www.openagrar.de/servlets/MCRFileNodeServlet/openagrar_derivate_00013044/SD19925.pdf |
op_rights |
only signed in user all rights reserved info:eu-repo/semantics/openAccess |
_version_ |
1766374586307313664 |