Enhanced Passive Bat Rabies Surveillance in Indigenous Bat Species from Germany - A Retrospective Study

In Germany, rabies in bats is a notifiable zoonotic disease, which is caused by European bat lyssaviruses type 1 and 2 (EBLV-1 and 2), and the recently discovered new lyssavirus species Bokeloh bat lyssavirus (BBLV). As the understanding of bat rabies in insectivorous bat species is limited, in addi...

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Published in:PLoS Neglected Tropical Diseases
Main Authors: Schatz, Juliane, Freuling, Conrad Martin, Auer, E., Goharriz, H., Harbusch, C., Johnson, N., Kaipf, I., Mettenleiter, Thomas C., Mühldorfer, K., Mühle, R.-U., Ohlendorf, B., Pott-Dörfer, B., Prüger, J., Sheikh Ali, Hanan, Stiefel, D., Teubner, J., Ulrich, Rainer G., Wibbelt, G., Müller, Thomas
Format: Article in Journal/Newspaper
Language:English
Published: 2014
Subjects:
Online Access:https://doi.org/10.1371/journal.pntd.0002835
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spelling ftopenagrar:oai:www.openagrar.de:openagrar_mods_00002810 2024-09-15T18:27:25+00:00 Enhanced Passive Bat Rabies Surveillance in Indigenous Bat Species from Germany - A Retrospective Study Schatz, Juliane Freuling, Conrad Martin Auer, E. Goharriz, H. Harbusch, C. Johnson, N. Kaipf, I. Mettenleiter, Thomas C. Mühldorfer, K. Mühle, R.-U. Ohlendorf, B. Pott-Dörfer, B. Prüger, J. Sheikh Ali, Hanan Stiefel, D. Teubner, J. Ulrich, Rainer G. Wibbelt, G. Müller, Thomas 2014-05-01 https://doi.org/10.1371/journal.pntd.0002835 https://www.openagrar.de/receive/openagrar_mods_00002810 https://www.openagrar.de/servlets/MCRFileNodeServlet/Document_derivate_00002791/SD2014159.pdf http://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0002835 eng eng PLoS neglected tropical diseases -- PLoS Negl Trop Dis -- 1935-2735 -- 1935-2727 -- 2429704-5 -- http://www.plosntds.org/ -- http://www.bibliothek.uni-regensburg.de/ezeit/?2429704 https://doi.org/10.1371/journal.pntd.0002835 https://www.openagrar.de/receive/openagrar_mods_00002810 https://www.openagrar.de/servlets/MCRFileNodeServlet/Document_derivate_00002791/SD2014159.pdf http://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0002835 public info:eu-repo/semantics/openAccess article Text ddc:610 article Text doc-type:article 2014 ftopenagrar https://doi.org/10.1371/journal.pntd.0002835 2024-07-08T23:56:23Z In Germany, rabies in bats is a notifiable zoonotic disease, which is caused by European bat lyssaviruses type 1 and 2 (EBLV-1 and 2), and the recently discovered new lyssavirus species Bokeloh bat lyssavirus (BBLV). As the understanding of bat rabies in insectivorous bat species is limited, in addition to routine bat rabies diagnosis, an enhanced passive surveillance study, i.e. the retrospective investigation of dead bats that had not been tested for rabies, was initiated in 1998 to study the distribution, abundance and epidemiology of lyssavirus infections in bats from Germany. A total number of 5478 individuals representing 21 bat species within two families were included in this study. The Noctule bat (Nyctalus noctula) and the Common pipistrelle (Pipistrellus pipistrellus) represented the most specimens submitted. Of all investigated bats, 1.17% tested positive for lyssaviruses using the fluorescent antibody test (FAT). The vast majority of positive cases was identified as EBLV-1, predominately associated with the Serotine bat (Eptesicus serotinus). However, rabies cases in other species, i.e. Nathusius' pipistrelle bat (Pipistrellus nathusii), P. pipistrellus and Brown long-eared bat (Plecotus auritus) were also characterized as EBLV-1. In contrast, EBLV-2 was isolated from three Daubenton's bats (Myotis daubentonii). These three cases contribute significantly to the understanding of EBLV-2 infections in Germany as only one case had been reported prior to this study. This enhanced passive surveillance indicated that besides known reservoir species, further bat species are affected by lyssavirus infections. Given the increasing diversity of lyssaviruses and bats as reservoir host species worldwide, lyssavirus positive specimens, i.e. both bat and virus need to be confirmed by molecular techniques. Article in Journal/Newspaper Nyctalus noctula Pipistrellus nathusii Pipistrellus pipistrellus OpenAgrar (OA) PLoS Neglected Tropical Diseases 8 5 e2835
institution Open Polar
collection OpenAgrar (OA)
op_collection_id ftopenagrar
language English
topic article
Text
ddc:610
spellingShingle article
Text
ddc:610
Schatz, Juliane
Freuling, Conrad Martin
Auer, E.
Goharriz, H.
Harbusch, C.
Johnson, N.
Kaipf, I.
Mettenleiter, Thomas C.
Mühldorfer, K.
Mühle, R.-U.
Ohlendorf, B.
Pott-Dörfer, B.
Prüger, J.
Sheikh Ali, Hanan
Stiefel, D.
Teubner, J.
Ulrich, Rainer G.
Wibbelt, G.
Müller, Thomas
Enhanced Passive Bat Rabies Surveillance in Indigenous Bat Species from Germany - A Retrospective Study
topic_facet article
Text
ddc:610
description In Germany, rabies in bats is a notifiable zoonotic disease, which is caused by European bat lyssaviruses type 1 and 2 (EBLV-1 and 2), and the recently discovered new lyssavirus species Bokeloh bat lyssavirus (BBLV). As the understanding of bat rabies in insectivorous bat species is limited, in addition to routine bat rabies diagnosis, an enhanced passive surveillance study, i.e. the retrospective investigation of dead bats that had not been tested for rabies, was initiated in 1998 to study the distribution, abundance and epidemiology of lyssavirus infections in bats from Germany. A total number of 5478 individuals representing 21 bat species within two families were included in this study. The Noctule bat (Nyctalus noctula) and the Common pipistrelle (Pipistrellus pipistrellus) represented the most specimens submitted. Of all investigated bats, 1.17% tested positive for lyssaviruses using the fluorescent antibody test (FAT). The vast majority of positive cases was identified as EBLV-1, predominately associated with the Serotine bat (Eptesicus serotinus). However, rabies cases in other species, i.e. Nathusius' pipistrelle bat (Pipistrellus nathusii), P. pipistrellus and Brown long-eared bat (Plecotus auritus) were also characterized as EBLV-1. In contrast, EBLV-2 was isolated from three Daubenton's bats (Myotis daubentonii). These three cases contribute significantly to the understanding of EBLV-2 infections in Germany as only one case had been reported prior to this study. This enhanced passive surveillance indicated that besides known reservoir species, further bat species are affected by lyssavirus infections. Given the increasing diversity of lyssaviruses and bats as reservoir host species worldwide, lyssavirus positive specimens, i.e. both bat and virus need to be confirmed by molecular techniques.
format Article in Journal/Newspaper
author Schatz, Juliane
Freuling, Conrad Martin
Auer, E.
Goharriz, H.
Harbusch, C.
Johnson, N.
Kaipf, I.
Mettenleiter, Thomas C.
Mühldorfer, K.
Mühle, R.-U.
Ohlendorf, B.
Pott-Dörfer, B.
Prüger, J.
Sheikh Ali, Hanan
Stiefel, D.
Teubner, J.
Ulrich, Rainer G.
Wibbelt, G.
Müller, Thomas
author_facet Schatz, Juliane
Freuling, Conrad Martin
Auer, E.
Goharriz, H.
Harbusch, C.
Johnson, N.
Kaipf, I.
Mettenleiter, Thomas C.
Mühldorfer, K.
Mühle, R.-U.
Ohlendorf, B.
Pott-Dörfer, B.
Prüger, J.
Sheikh Ali, Hanan
Stiefel, D.
Teubner, J.
Ulrich, Rainer G.
Wibbelt, G.
Müller, Thomas
author_sort Schatz, Juliane
title Enhanced Passive Bat Rabies Surveillance in Indigenous Bat Species from Germany - A Retrospective Study
title_short Enhanced Passive Bat Rabies Surveillance in Indigenous Bat Species from Germany - A Retrospective Study
title_full Enhanced Passive Bat Rabies Surveillance in Indigenous Bat Species from Germany - A Retrospective Study
title_fullStr Enhanced Passive Bat Rabies Surveillance in Indigenous Bat Species from Germany - A Retrospective Study
title_full_unstemmed Enhanced Passive Bat Rabies Surveillance in Indigenous Bat Species from Germany - A Retrospective Study
title_sort enhanced passive bat rabies surveillance in indigenous bat species from germany - a retrospective study
publishDate 2014
url https://doi.org/10.1371/journal.pntd.0002835
https://www.openagrar.de/receive/openagrar_mods_00002810
https://www.openagrar.de/servlets/MCRFileNodeServlet/Document_derivate_00002791/SD2014159.pdf
http://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0002835
genre Nyctalus noctula
Pipistrellus nathusii
Pipistrellus pipistrellus
genre_facet Nyctalus noctula
Pipistrellus nathusii
Pipistrellus pipistrellus
op_relation PLoS neglected tropical diseases -- PLoS Negl Trop Dis -- 1935-2735 -- 1935-2727 -- 2429704-5 -- http://www.plosntds.org/ -- http://www.bibliothek.uni-regensburg.de/ezeit/?2429704
https://doi.org/10.1371/journal.pntd.0002835
https://www.openagrar.de/receive/openagrar_mods_00002810
https://www.openagrar.de/servlets/MCRFileNodeServlet/Document_derivate_00002791/SD2014159.pdf
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