Polychlorinated Naphthalenes in Foods from the French Market: Occurrence, Dietary Exposure, and Evaluation of Relative Contributions to Dioxin-like Contaminants

• Published in: Environmental Science & Technology
• Main Authors: Godéré, Mathilde, Cariou, Ronan, Padioleau, Antonin, Vénisseau, Anaïs, Marchand, Philippe, Brosseau, Aline, Vaccher, Vincent, Le Bizec, Bruno, Dervilly, Gaud
• Other Authors: Laboratoire d'étude des Résidus et Contaminants dans les Aliments (LABERCA), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)
• Format: Article in Journal/Newspaper
• Language: English
• Published: HAL CCSD 2024
• Subjects: Polychlorinated Naphthalenes; Dioxin-liketoxicity; Food; Dietary Exposure; Occurrence; [CHIM]Chemical Sciences; North East Atlantic
• Online Access: https://oniris.hal.science/hal-04401384; https://doi.org/10.1021/acs.est.3c07838

International audience Despite the growing interest in PCNs and the dioxin-like toxicity exhibited by a number of congeners, a comprehensive assessment of their contribution to the cocktail of dioxin-like contaminants is still lacking. To address such a shortcoming, this study investigated the PCN contamination in foodstuffs recently acquired in France, together with that of the regulatory polychlorinated dibenzodioxins/furans (PCDD/Fs) and polychlorinated biphenyls (PCBs). PCNs were ubiquitous at levels (& sum;70 PCNs = 2.5-150 pg g(-1) wet weight) similar to those reported in other countries, with maximum concentrations observed in fish and fishery products from the North-East Atlantic Ocean. Their congener patterns further suggested unintentional releases of PCNs, while those of the other foodstuffs were correlated to the historical PCN profiles. Low risk from dietary exposure was estimated (& sum;70 PCNs-EDIs of 60-360 pg kg(-1) bw d(-1), & sum;24 PCNs-TEQ-EDIs of 8 x 10(-3)-2.2 x 10(-2) pg TEQ kg(-1) bw d(-1)), with milk and dairy products being the highest contributors, followed by meat and meat products. Finally, the rather high contributions of PCNs to the total PCNs+PCDD/Fs+PCBs concentrations (0.9-50%, average of 9%) and the toxic equivalents (0.2-24%, average of 5%) show that these substances are not minor components of the PCNs+PCDD/Fs+PCBs cocktail.