Characterization of MHC class II genes in the critically endangered European eel (Anguilla anguilla)
Many exploited fish species are threatened with collapse and the European eel is no exception. Its abundance has declined dramatically and various reasons account for this, among them the introduction of the invasive swim bladder nematode Anguillicola crassus. For developing an adequate immune respo...
Published in: | Conservation Genetics Resources |
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Online Access: | https://oceanrep.geomar.de/id/eprint/30475/ https://oceanrep.geomar.de/id/eprint/30475/1/art_10.1007_s12686-015-0501-z.pdf https://doi.org/10.1007/s12686-015-0501-z |
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ftoceanrep:oai:oceanrep.geomar.de:30475 2023-05-15T13:27:34+02:00 Characterization of MHC class II genes in the critically endangered European eel (Anguilla anguilla) Bracamonte, Seraina E. Baltazar-Soares, Miguel Eizaguirre, Christophe 2015-12-01 text https://oceanrep.geomar.de/id/eprint/30475/ https://oceanrep.geomar.de/id/eprint/30475/1/art_10.1007_s12686-015-0501-z.pdf https://doi.org/10.1007/s12686-015-0501-z en eng Springer https://oceanrep.geomar.de/id/eprint/30475/1/art_10.1007_s12686-015-0501-z.pdf Bracamonte, S. E., Baltazar-Soares, M. and Eizaguirre, C. (2015) Characterization of MHC class II genes in the critically endangered European eel (Anguilla anguilla). Conservation Genetics Resources, 7 (4). pp. 859-870. DOI 10.1007/s12686-015-0501-z <https://doi.org/10.1007/s12686-015-0501-z>. doi:10.1007/s12686-015-0501-z info:eu-repo/semantics/restrictedAccess Article PeerReviewed 2015 ftoceanrep https://doi.org/10.1007/s12686-015-0501-z 2023-04-07T15:22:07Z Many exploited fish species are threatened with collapse and the European eel is no exception. Its abundance has declined dramatically and various reasons account for this, among them the introduction of the invasive swim bladder nematode Anguillicola crassus. For developing an adequate immune response against this parasite, variation at the genes of the major histocompatibility complex (MHC), a key component of the adaptive immune system, might be essential and assessing their diversity might provide critical information for improving conservation strategies. Here, we characterized the MHC class II of the European eel. We provide evidence for relatively high diversity at both MHC IIA and MHC IIB, which contrasts with findings for other endangered species. Furthermore, both genes show signs of site-specific positive selection. The absence of overall positive selection at MHC IIB might, however, suggests that demographic shifts have negatively impacted that gene, thereby possibly reducing the adaptive potential of the European eel. Article in Journal/Newspaper Anguilla anguilla European eel OceanRep (GEOMAR Helmholtz Centre für Ocean Research Kiel) Conservation Genetics Resources 7 4 859 870 |
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Open Polar |
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OceanRep (GEOMAR Helmholtz Centre für Ocean Research Kiel) |
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ftoceanrep |
language |
English |
description |
Many exploited fish species are threatened with collapse and the European eel is no exception. Its abundance has declined dramatically and various reasons account for this, among them the introduction of the invasive swim bladder nematode Anguillicola crassus. For developing an adequate immune response against this parasite, variation at the genes of the major histocompatibility complex (MHC), a key component of the adaptive immune system, might be essential and assessing their diversity might provide critical information for improving conservation strategies. Here, we characterized the MHC class II of the European eel. We provide evidence for relatively high diversity at both MHC IIA and MHC IIB, which contrasts with findings for other endangered species. Furthermore, both genes show signs of site-specific positive selection. The absence of overall positive selection at MHC IIB might, however, suggests that demographic shifts have negatively impacted that gene, thereby possibly reducing the adaptive potential of the European eel. |
format |
Article in Journal/Newspaper |
author |
Bracamonte, Seraina E. Baltazar-Soares, Miguel Eizaguirre, Christophe |
spellingShingle |
Bracamonte, Seraina E. Baltazar-Soares, Miguel Eizaguirre, Christophe Characterization of MHC class II genes in the critically endangered European eel (Anguilla anguilla) |
author_facet |
Bracamonte, Seraina E. Baltazar-Soares, Miguel Eizaguirre, Christophe |
author_sort |
Bracamonte, Seraina E. |
title |
Characterization of MHC class II genes in the critically endangered European eel (Anguilla anguilla) |
title_short |
Characterization of MHC class II genes in the critically endangered European eel (Anguilla anguilla) |
title_full |
Characterization of MHC class II genes in the critically endangered European eel (Anguilla anguilla) |
title_fullStr |
Characterization of MHC class II genes in the critically endangered European eel (Anguilla anguilla) |
title_full_unstemmed |
Characterization of MHC class II genes in the critically endangered European eel (Anguilla anguilla) |
title_sort |
characterization of mhc class ii genes in the critically endangered european eel (anguilla anguilla) |
publisher |
Springer |
publishDate |
2015 |
url |
https://oceanrep.geomar.de/id/eprint/30475/ https://oceanrep.geomar.de/id/eprint/30475/1/art_10.1007_s12686-015-0501-z.pdf https://doi.org/10.1007/s12686-015-0501-z |
genre |
Anguilla anguilla European eel |
genre_facet |
Anguilla anguilla European eel |
op_relation |
https://oceanrep.geomar.de/id/eprint/30475/1/art_10.1007_s12686-015-0501-z.pdf Bracamonte, S. E., Baltazar-Soares, M. and Eizaguirre, C. (2015) Characterization of MHC class II genes in the critically endangered European eel (Anguilla anguilla). Conservation Genetics Resources, 7 (4). pp. 859-870. DOI 10.1007/s12686-015-0501-z <https://doi.org/10.1007/s12686-015-0501-z>. doi:10.1007/s12686-015-0501-z |
op_rights |
info:eu-repo/semantics/restrictedAccess |
op_doi |
https://doi.org/10.1007/s12686-015-0501-z |
container_title |
Conservation Genetics Resources |
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7 |
container_issue |
4 |
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859 |
op_container_end_page |
870 |
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1766399202787590144 |