Occupational physical activity and risk of mortality in women and men: the Tromsø Study 1986–2021
Objective Associations between occupational physical activity (OPA) and mortality risks are inconclusive. We aimed to examine associations between (1) OPA separately and (2) jointly with leisure time physical activity (LTPA), and risk of all-cause, cardiovascular disease (CVD) and cancer mortality,...
Published in: | British Journal of Sports Medicine |
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Online Access: | https://hdl.handle.net/11250/3109254 https://doi.org/10.1136/bjsports-2023-107282 |
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ftntnutrondheimi:oai:ntnuopen.ntnu.no:11250/3109254 2024-01-28T10:09:33+01:00 Occupational physical activity and risk of mortality in women and men: the Tromsø Study 1986–2021 Sagelv, Edvard Hamnvik Dalene, Knut Eirik Eggen, Anne Elise Ekelund, Ulf Fimland, Marius Steiro Heitmann, Kim Arne Holtermann, Andreas Johansen, Kristoffer Robin Løchen, Maja-Lisa Morseth, Bente Wilsgaard, Tom 2023 application/pdf https://hdl.handle.net/11250/3109254 https://doi.org/10.1136/bjsports-2023-107282 eng eng BMJ Publishing Group British Journal of Sports Medicine. 2023, . urn:issn:0306-3674 https://hdl.handle.net/11250/3109254 https://doi.org/10.1136/bjsports-2023-107282 cristin:2191268 Navngivelse 4.0 Internasjonal http://creativecommons.org/licenses/by/4.0/deed.no Copyright © 2023 BMJ Publishing Group Ltd 10 British Journal of Sports Medicine Peer reviewed Journal article 2023 ftntnutrondheimi https://doi.org/10.1136/bjsports-2023-107282 2024-01-03T23:46:52Z Objective Associations between occupational physical activity (OPA) and mortality risks are inconclusive. We aimed to examine associations between (1) OPA separately and (2) jointly with leisure time physical activity (LTPA), and risk of all-cause, cardiovascular disease (CVD) and cancer mortality, over four decades with updated exposure and covariates every 6–8 years. Methods Adults aged 20–65 years from the Tromsø Study surveys Tromsø3-Tromsø7 (1986–2016) were included. We categorised OPA as low (sedentary), moderate (walking work), high (walking+lifting work) or very high (heavy manual labour) and LTPA as inactive, moderate and vigorous. We used Cox/Fine and Gray regressions to examine associations, adjusted for age, body mass index, smoking, education, diet, alcohol and LTPA (aim 1 only). Results Of 29 605 participants with 44 140 total observations, 4131 (14.0%) died, 1057 (25.6%) from CVD and 1660 (40.4%) from cancer, during follow-up (median: 29.1 years, 25th–75th: 16.5.1–35.3). In men, compared with low OPA, high OPA was associated with lower all-cause (HR 0.83, 95% CI 0.74 to 0.92) and CVD (subdistributed HR (SHR) 0.68, 95% CI 0.54 to 0.84) but not cancer mortality (SHR 0.99, 95% CI 0.84 to 1.19), while no association was observed for moderate or very high OPA. In joint analyses using inactive LTPA and low OPA as reference, vigorous LTPA was associated with lower all-cause mortality combined with low (HR 0.75, 95% CI 0.64 to 0.89), high (HR 0.67, 95% CI 0.54 to 0.82) and very high OPA (HR 0.74, 95% CI 0.58 to 0.94), but not with moderate OPA. In women, there were no associations between OPA, or combined OPA and LTPA, with mortality. Conclusion High OPA, but not moderate and very high OPA, was associated with lower all-cause and CVD mortality risk in men but not in women. Vigorous LTPA was associated with lower mortality risk in men with low, high and very high OPA, but not moderate OPA. acceptedVersion Article in Journal/Newspaper Tromsø NTNU Open Archive (Norwegian University of Science and Technology) Tromsø British Journal of Sports Medicine 58 2 81 88 |
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Open Polar |
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NTNU Open Archive (Norwegian University of Science and Technology) |
op_collection_id |
ftntnutrondheimi |
language |
English |
description |
Objective Associations between occupational physical activity (OPA) and mortality risks are inconclusive. We aimed to examine associations between (1) OPA separately and (2) jointly with leisure time physical activity (LTPA), and risk of all-cause, cardiovascular disease (CVD) and cancer mortality, over four decades with updated exposure and covariates every 6–8 years. Methods Adults aged 20–65 years from the Tromsø Study surveys Tromsø3-Tromsø7 (1986–2016) were included. We categorised OPA as low (sedentary), moderate (walking work), high (walking+lifting work) or very high (heavy manual labour) and LTPA as inactive, moderate and vigorous. We used Cox/Fine and Gray regressions to examine associations, adjusted for age, body mass index, smoking, education, diet, alcohol and LTPA (aim 1 only). Results Of 29 605 participants with 44 140 total observations, 4131 (14.0%) died, 1057 (25.6%) from CVD and 1660 (40.4%) from cancer, during follow-up (median: 29.1 years, 25th–75th: 16.5.1–35.3). In men, compared with low OPA, high OPA was associated with lower all-cause (HR 0.83, 95% CI 0.74 to 0.92) and CVD (subdistributed HR (SHR) 0.68, 95% CI 0.54 to 0.84) but not cancer mortality (SHR 0.99, 95% CI 0.84 to 1.19), while no association was observed for moderate or very high OPA. In joint analyses using inactive LTPA and low OPA as reference, vigorous LTPA was associated with lower all-cause mortality combined with low (HR 0.75, 95% CI 0.64 to 0.89), high (HR 0.67, 95% CI 0.54 to 0.82) and very high OPA (HR 0.74, 95% CI 0.58 to 0.94), but not with moderate OPA. In women, there were no associations between OPA, or combined OPA and LTPA, with mortality. Conclusion High OPA, but not moderate and very high OPA, was associated with lower all-cause and CVD mortality risk in men but not in women. Vigorous LTPA was associated with lower mortality risk in men with low, high and very high OPA, but not moderate OPA. acceptedVersion |
format |
Article in Journal/Newspaper |
author |
Sagelv, Edvard Hamnvik Dalene, Knut Eirik Eggen, Anne Elise Ekelund, Ulf Fimland, Marius Steiro Heitmann, Kim Arne Holtermann, Andreas Johansen, Kristoffer Robin Løchen, Maja-Lisa Morseth, Bente Wilsgaard, Tom |
spellingShingle |
Sagelv, Edvard Hamnvik Dalene, Knut Eirik Eggen, Anne Elise Ekelund, Ulf Fimland, Marius Steiro Heitmann, Kim Arne Holtermann, Andreas Johansen, Kristoffer Robin Løchen, Maja-Lisa Morseth, Bente Wilsgaard, Tom Occupational physical activity and risk of mortality in women and men: the Tromsø Study 1986–2021 |
author_facet |
Sagelv, Edvard Hamnvik Dalene, Knut Eirik Eggen, Anne Elise Ekelund, Ulf Fimland, Marius Steiro Heitmann, Kim Arne Holtermann, Andreas Johansen, Kristoffer Robin Løchen, Maja-Lisa Morseth, Bente Wilsgaard, Tom |
author_sort |
Sagelv, Edvard Hamnvik |
title |
Occupational physical activity and risk of mortality in women and men: the Tromsø Study 1986–2021 |
title_short |
Occupational physical activity and risk of mortality in women and men: the Tromsø Study 1986–2021 |
title_full |
Occupational physical activity and risk of mortality in women and men: the Tromsø Study 1986–2021 |
title_fullStr |
Occupational physical activity and risk of mortality in women and men: the Tromsø Study 1986–2021 |
title_full_unstemmed |
Occupational physical activity and risk of mortality in women and men: the Tromsø Study 1986–2021 |
title_sort |
occupational physical activity and risk of mortality in women and men: the tromsø study 1986–2021 |
publisher |
BMJ Publishing Group |
publishDate |
2023 |
url |
https://hdl.handle.net/11250/3109254 https://doi.org/10.1136/bjsports-2023-107282 |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_source |
10 British Journal of Sports Medicine |
op_relation |
British Journal of Sports Medicine. 2023, . urn:issn:0306-3674 https://hdl.handle.net/11250/3109254 https://doi.org/10.1136/bjsports-2023-107282 cristin:2191268 |
op_rights |
Navngivelse 4.0 Internasjonal http://creativecommons.org/licenses/by/4.0/deed.no Copyright © 2023 BMJ Publishing Group Ltd |
op_doi |
https://doi.org/10.1136/bjsports-2023-107282 |
container_title |
British Journal of Sports Medicine |
container_volume |
58 |
container_issue |
2 |
container_start_page |
81 |
op_container_end_page |
88 |
_version_ |
1789339598235631616 |