Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes)
The scavenger endothelial cells (SECs) of vertebrates are an important class of endocytic cells responsible for clearance of foreign and physiological waste macromolecules, partitioning in the immune system, functioning as a cellular powerplant by producing high energy metabolites like lactate and a...
Published in: | Fish & Shellfish Immunology |
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Online Access: | https://hdl.handle.net/11250/3107946 https://doi.org/10.1016/j.fsi.2023.109250 |
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ftntnutrondheimi:oai:ntnuopen.ntnu.no:11250/3107946 2024-01-14T10:08:33+01:00 Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes) Seternes, Tore Poppe, Trygve T Bøgwald, Jarl Lynghammar, Arve Dalmo, Roy Ambli 2023 application/pdf https://hdl.handle.net/11250/3107946 https://doi.org/10.1016/j.fsi.2023.109250 eng eng Elsevier B. V. urn:issn:1050-4648 https://hdl.handle.net/11250/3107946 https://doi.org/10.1016/j.fsi.2023.109250 cristin:2213891 Navngivelse 4.0 Internasjonal http://creativecommons.org/licenses/by/4.0/deed.no 144 Fish and Shellfish Immunology 109250 Peer reviewed Journal article 2023 ftntnutrondheimi https://doi.org/10.1016/j.fsi.2023.109250 2023-12-20T23:46:51Z The scavenger endothelial cells (SECs) of vertebrates are an important class of endocytic cells responsible for clearance of foreign and physiological waste macromolecules, partitioning in the immune system, functioning as a cellular powerplant by producing high energy metabolites like lactate and acetate. All animal phyla possess SECs, but the tissue localization of SECs has only been investigated in a limited number of species. By using a specific ligand for scavenger receptors (formalin treated bovine serum albumin), the study revealed that in all tetrapod species (amphibia, reptiles, birds and mammals) the SECs were found lining the sinusoids of the liver. No SECs were found in the liver of any of the bony fishes (Osteichthyes) investigated. Interestingly, we found the SECs not only to be located in the heart of marine species but also in some freshwater species such as Lota lota, Percichthys trucha and Perca fluviatilis. In some fish species, the SECs were found both in the heart and/or kidney in a number of marine and freshwater fishes, whereas in some marine, diadromous and freshwater fishes the SECs were confined only to the kidney tissue. However, from these results it can be suggested that there is neither a clear phylogenetic trend when it came to anatomical localization of SECs nor any pattern in terms of habitat (salinity preferences). publishedVersion Article in Journal/Newspaper Lota lota lota NTNU Open Archive (Norwegian University of Science and Technology) Fish & Shellfish Immunology 144 109250 |
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Open Polar |
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NTNU Open Archive (Norwegian University of Science and Technology) |
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ftntnutrondheimi |
language |
English |
description |
The scavenger endothelial cells (SECs) of vertebrates are an important class of endocytic cells responsible for clearance of foreign and physiological waste macromolecules, partitioning in the immune system, functioning as a cellular powerplant by producing high energy metabolites like lactate and acetate. All animal phyla possess SECs, but the tissue localization of SECs has only been investigated in a limited number of species. By using a specific ligand for scavenger receptors (formalin treated bovine serum albumin), the study revealed that in all tetrapod species (amphibia, reptiles, birds and mammals) the SECs were found lining the sinusoids of the liver. No SECs were found in the liver of any of the bony fishes (Osteichthyes) investigated. Interestingly, we found the SECs not only to be located in the heart of marine species but also in some freshwater species such as Lota lota, Percichthys trucha and Perca fluviatilis. In some fish species, the SECs were found both in the heart and/or kidney in a number of marine and freshwater fishes, whereas in some marine, diadromous and freshwater fishes the SECs were confined only to the kidney tissue. However, from these results it can be suggested that there is neither a clear phylogenetic trend when it came to anatomical localization of SECs nor any pattern in terms of habitat (salinity preferences). publishedVersion |
format |
Article in Journal/Newspaper |
author |
Seternes, Tore Poppe, Trygve T Bøgwald, Jarl Lynghammar, Arve Dalmo, Roy Ambli |
spellingShingle |
Seternes, Tore Poppe, Trygve T Bøgwald, Jarl Lynghammar, Arve Dalmo, Roy Ambli Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes) |
author_facet |
Seternes, Tore Poppe, Trygve T Bøgwald, Jarl Lynghammar, Arve Dalmo, Roy Ambli |
author_sort |
Seternes, Tore |
title |
Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes) |
title_short |
Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes) |
title_full |
Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes) |
title_fullStr |
Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes) |
title_full_unstemmed |
Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes) |
title_sort |
anatomical distribution of scavenger endothelial cells in bony fishes (osteichthyes) |
publisher |
Elsevier B. V. |
publishDate |
2023 |
url |
https://hdl.handle.net/11250/3107946 https://doi.org/10.1016/j.fsi.2023.109250 |
genre |
Lota lota lota |
genre_facet |
Lota lota lota |
op_source |
144 Fish and Shellfish Immunology 109250 |
op_relation |
urn:issn:1050-4648 https://hdl.handle.net/11250/3107946 https://doi.org/10.1016/j.fsi.2023.109250 cristin:2213891 |
op_rights |
Navngivelse 4.0 Internasjonal http://creativecommons.org/licenses/by/4.0/deed.no |
op_doi |
https://doi.org/10.1016/j.fsi.2023.109250 |
container_title |
Fish & Shellfish Immunology |
container_volume |
144 |
container_start_page |
109250 |
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1788062971311685632 |