Pre-extinction Demographic Stability and Genomic Signatures of Adaptation in the Woolly Rhinoceros
Ancient DNA has significantly improved our understanding of the evolution and population history of extinct megafauna. However, few studies have used complete ancient genomes to examine species responses to climate change prior to extinction. The woolly rhinoceros (Coelodonta antiquitatis) was a col...
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Enheten för bioinformatik och genetik
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ftnrm:oai:DiVA.org:nrm-4091 2023-05-15T15:11:31+02:00 Pre-extinction Demographic Stability and Genomic Signatures of Adaptation in the Woolly Rhinoceros Lord, Edana Dussex, Nicolas Kierczak, Marcin Diez-del-Molino, David Ryder, Oliver A. Stanton, David W. G. Gilbert, M. Thomas P. Sanchez-Barreiro, Fatima Zhang, Guojie Sinding, Mikkel-Holger S. Lorenzen, Eline D. Willerslev, Eske Protopopov, Albert Shidlovskiy, Fedor Fedorov, Sergey Bocherens, Herve Nathan, Senthilvel K. S. S. Goossens, Benoit van der Plicht, Johannes Chan, Yvonne L. Prost, Stefan Potapova, Olga Kirillova, Irina Lister, Adrian M. Heintzman, Peter D. Kapp, Joshua D. Shapiro, Beth Vartanyan, Sergey Gotherstrom, Anders Dalen, Love 2020 application/pdf http://urn.kb.se/resolve?urn=urn:nbn:se:nrm:diva-4091 https://doi.org/10.1016/j.cub.2020.07.046 eng eng Enheten för bioinformatik och genetik Current Biology, 0960-9822, 2020, 30:19, http://urn.kb.se/resolve?urn=urn:nbn:se:nrm:diva-4091 doi:10.1016/j.cub.2020.07.046 info:eu-repo/semantics/openAccess Evolutionary Biology Evolutionsbiologi Article in journal info:eu-repo/semantics/article text 2020 ftnrm https://doi.org/10.1016/j.cub.2020.07.046 2021-10-08T07:21:22Z Ancient DNA has significantly improved our understanding of the evolution and population history of extinct megafauna. However, few studies have used complete ancient genomes to examine species responses to climate change prior to extinction. The woolly rhinoceros (Coelodonta antiquitatis) was a cold-adapted megaherbivore widely distributed across northern Eurasia during the Late Pleistocene and became extinct approximately 14 thousand years before present (ka BP). While humans and climate change have been proposed as potential causes of extinction [1-3], knowledge is limited on how the woolly rhinoceros was impacted by human arrival and climatic fluctuations [2]. Here, we use one complete nuclear genome and 14 mitogenomes to investigate the demographic history of woolly rhinoceros leading up to its extinction. Unlike other northern megafauna, the effective population size of woolly rhinoceros likely increased at 29.7 ka BP and subsequently remained stable until close to the species’ extinction. Analysis of the nuclear genome from a similar to 18.5-ka-old specimen did not indicate any increased inbreeding or reduced genetic diversity, suggesting that the population size remained steady for more than 13 ka following the arrival of humans [4]. The population contraction leading to extinction of the woolly rhinoceros may have thus been sudden and mostly driven by rapid warming in the Bolling-Allerod interstadial. Furthermore, we identify woolly rhinoceros-specific adaptations to arctic climate, similar to those of the woolly mammoth. This study highlights how species respond differently to climatic fluctuations and further illustrates the potential of palaeogenomics to study the evolutionary history of extinct species. Article in Journal/Newspaper Arctic Climate change Swedish Museum of Natural History: Publications (DiVA) Arctic Current Biology 30 19 3871 3879.e7 |
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Swedish Museum of Natural History: Publications (DiVA) |
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language |
English |
topic |
Evolutionary Biology Evolutionsbiologi |
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Evolutionary Biology Evolutionsbiologi Lord, Edana Dussex, Nicolas Kierczak, Marcin Diez-del-Molino, David Ryder, Oliver A. Stanton, David W. G. Gilbert, M. Thomas P. Sanchez-Barreiro, Fatima Zhang, Guojie Sinding, Mikkel-Holger S. Lorenzen, Eline D. Willerslev, Eske Protopopov, Albert Shidlovskiy, Fedor Fedorov, Sergey Bocherens, Herve Nathan, Senthilvel K. S. S. Goossens, Benoit van der Plicht, Johannes Chan, Yvonne L. Prost, Stefan Potapova, Olga Kirillova, Irina Lister, Adrian M. Heintzman, Peter D. Kapp, Joshua D. Shapiro, Beth Vartanyan, Sergey Gotherstrom, Anders Dalen, Love Pre-extinction Demographic Stability and Genomic Signatures of Adaptation in the Woolly Rhinoceros |
topic_facet |
Evolutionary Biology Evolutionsbiologi |
description |
Ancient DNA has significantly improved our understanding of the evolution and population history of extinct megafauna. However, few studies have used complete ancient genomes to examine species responses to climate change prior to extinction. The woolly rhinoceros (Coelodonta antiquitatis) was a cold-adapted megaherbivore widely distributed across northern Eurasia during the Late Pleistocene and became extinct approximately 14 thousand years before present (ka BP). While humans and climate change have been proposed as potential causes of extinction [1-3], knowledge is limited on how the woolly rhinoceros was impacted by human arrival and climatic fluctuations [2]. Here, we use one complete nuclear genome and 14 mitogenomes to investigate the demographic history of woolly rhinoceros leading up to its extinction. Unlike other northern megafauna, the effective population size of woolly rhinoceros likely increased at 29.7 ka BP and subsequently remained stable until close to the species’ extinction. Analysis of the nuclear genome from a similar to 18.5-ka-old specimen did not indicate any increased inbreeding or reduced genetic diversity, suggesting that the population size remained steady for more than 13 ka following the arrival of humans [4]. The population contraction leading to extinction of the woolly rhinoceros may have thus been sudden and mostly driven by rapid warming in the Bolling-Allerod interstadial. Furthermore, we identify woolly rhinoceros-specific adaptations to arctic climate, similar to those of the woolly mammoth. This study highlights how species respond differently to climatic fluctuations and further illustrates the potential of palaeogenomics to study the evolutionary history of extinct species. |
format |
Article in Journal/Newspaper |
author |
Lord, Edana Dussex, Nicolas Kierczak, Marcin Diez-del-Molino, David Ryder, Oliver A. Stanton, David W. G. Gilbert, M. Thomas P. Sanchez-Barreiro, Fatima Zhang, Guojie Sinding, Mikkel-Holger S. Lorenzen, Eline D. Willerslev, Eske Protopopov, Albert Shidlovskiy, Fedor Fedorov, Sergey Bocherens, Herve Nathan, Senthilvel K. S. S. Goossens, Benoit van der Plicht, Johannes Chan, Yvonne L. Prost, Stefan Potapova, Olga Kirillova, Irina Lister, Adrian M. Heintzman, Peter D. Kapp, Joshua D. Shapiro, Beth Vartanyan, Sergey Gotherstrom, Anders Dalen, Love |
author_facet |
Lord, Edana Dussex, Nicolas Kierczak, Marcin Diez-del-Molino, David Ryder, Oliver A. Stanton, David W. G. Gilbert, M. Thomas P. Sanchez-Barreiro, Fatima Zhang, Guojie Sinding, Mikkel-Holger S. Lorenzen, Eline D. Willerslev, Eske Protopopov, Albert Shidlovskiy, Fedor Fedorov, Sergey Bocherens, Herve Nathan, Senthilvel K. S. S. Goossens, Benoit van der Plicht, Johannes Chan, Yvonne L. Prost, Stefan Potapova, Olga Kirillova, Irina Lister, Adrian M. Heintzman, Peter D. Kapp, Joshua D. Shapiro, Beth Vartanyan, Sergey Gotherstrom, Anders Dalen, Love |
author_sort |
Lord, Edana |
title |
Pre-extinction Demographic Stability and Genomic Signatures of Adaptation in the Woolly Rhinoceros |
title_short |
Pre-extinction Demographic Stability and Genomic Signatures of Adaptation in the Woolly Rhinoceros |
title_full |
Pre-extinction Demographic Stability and Genomic Signatures of Adaptation in the Woolly Rhinoceros |
title_fullStr |
Pre-extinction Demographic Stability and Genomic Signatures of Adaptation in the Woolly Rhinoceros |
title_full_unstemmed |
Pre-extinction Demographic Stability and Genomic Signatures of Adaptation in the Woolly Rhinoceros |
title_sort |
pre-extinction demographic stability and genomic signatures of adaptation in the woolly rhinoceros |
publisher |
Enheten för bioinformatik och genetik |
publishDate |
2020 |
url |
http://urn.kb.se/resolve?urn=urn:nbn:se:nrm:diva-4091 https://doi.org/10.1016/j.cub.2020.07.046 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic Climate change |
genre_facet |
Arctic Climate change |
op_relation |
Current Biology, 0960-9822, 2020, 30:19, http://urn.kb.se/resolve?urn=urn:nbn:se:nrm:diva-4091 doi:10.1016/j.cub.2020.07.046 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1016/j.cub.2020.07.046 |
container_title |
Current Biology |
container_volume |
30 |
container_issue |
19 |
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3871 |
op_container_end_page |
3879.e7 |
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1766342357314174976 |