Robust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities.

• Published in: Nature Immunology
• Main Authors: Zhang, W, Kedzierski, L, Chua, B, Mayo, M, Lonzi, C, Rigas, V, Middleton, B, McQuilten, H, Rowntree, L, Allen, L, Purcell, R, Tan, H, Petersen, J, Chaurasia, P, Mordant, F, Pogorelyy, M, Minervina, A, Crawford, J, Perkins, G, Zhang, E, Gras, S, Clemens, E, Juno, J, Audsley, J, Khoury, D, Holmes, N, Thevarajan, I, Subbarao, K, Krammer, F, Cheng, A, Davenport, M, Grubor-Bauk, B, Coates, P, Christensen, B, Thomas, P, Wheatley, A, Kent, S, Rossjohn, J, Chung, A, Boffa, J, Miller, A, Lynar, S, Nelson, J, Nguyen, T, Davies, J, Kedzierska, K
• Format: Article in Journal/Newspaper
• Language: English
• Published: United States 2023
• Subjects: Clayton; Menzies; First Nations
• Online Access: https://hdl.handle.net/10137/12471; https://doi.org/10.1038/s41590-023-01508-y; https://www.ezpdhcs.nt.gov.au/login?url=https://www.ncbi.nlm.nih.gov/pubmed/37248417

High-risk groups, including Indigenous people, are at risk of severe COVID-19. Here we found that Australian First Nations peoples elicit effective immune responses to COVID-19 BNT162b2 vaccination, including neutralizing antibodies, receptor-binding domain (RBD) antibodies, SARS-CoV-2 spike-specifi...