Effects of chronic sub‐lethal nitrite exposure at high water chloride concentration on Atlantic salmon (Salmo salar, Linnaeus 1758) parr
The present study examined the protective effects of water chloride (Cl−) towards nitrite toxicity in Atlantic salmon parr during 84‐day long nitrite exposure. Effects on growth, histology, blood indices and gene expression were studied at a fixed nominal Cl− concentration of 200 mg/L and at several...
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Online Access: | http://hdl.handle.net/11250/2616669 https://doi.org/10.1111/are.14226 |
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ftnofima:oai:nofima.brage.unit.no:11250/2616669 2023-05-15T15:30:08+02:00 Effects of chronic sub‐lethal nitrite exposure at high water chloride concentration on Atlantic salmon (Salmo salar, Linnaeus 1758) parr Gutiérrez, Xavier Andrés Kolarevic, Jelena Takle, Harald Rune Bæverfjord, Grete Ytteborg, Elisabeth Terjesen, Bendik Fyhn 2019 application/pdf http://hdl.handle.net/11250/2616669 https://doi.org/10.1111/are.14226 eng eng Norges forskningsråd: 237856 Nofima AS: 11244 Norges forskningsråd: 186913 Aquaculture Research. 2019, 50 2687-2697. urn:issn:1355-557X http://hdl.handle.net/11250/2616669 https://doi.org/10.1111/are.14226 cristin:1711038 2687-2697 50 Aquaculture Research Journal article Peer reviewed 2019 ftnofima https://doi.org/10.1111/are.14226 2022-11-18T06:51:01Z The present study examined the protective effects of water chloride (Cl−) towards nitrite toxicity in Atlantic salmon parr during 84‐day long nitrite exposure. Effects on growth, histology, blood indices and gene expression were studied at a fixed nominal Cl− concentration of 200 mg/L and at several water nitrite concentrations (0, 0.5, 2, 5 and 10 mg/L NO2−–N). The specific growth rate was significantly reduced during the first three weeks at a Cl:NO2−–N ratio of 21:1, suggesting the activation of coping mechanisms at the later stages of the experiment. No significant effect of nitrite on gill histology and mortality was found. Nitrite accumulated in plasma; however, a Cl:NO2−–N ratio of 104:1 or higher prevented nitrite entry. The concentration of NO2−–N in plasma was significantly reduced at the end of the study, supporting the hypothesis of coping mechanisms. Cystic fibrosis transmembrane conductance regulator (cftr)‐1 showed a significant up‐regulation at highest nitrite concentration on day 22, and in three of the highest exposure groups at the end of the experiment. Our findings suggest that a Cl:NO2−–N ratio above 104:1 should be maintained through episodes of nitrite accumulation in water during the production of Atlantic salmon parr. Effects of chronic sub‐lethal nitrite exposure at high water chloride concentration on Atlantic salmon (Salmo salar, Linnaeus 1758) parr submittedVersion Article in Journal/Newspaper Atlantic salmon Salmo salar Nofima Knowledge Archive (Brage) Aquaculture Research 50 9 2687 2697 |
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Open Polar |
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Nofima Knowledge Archive (Brage) |
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ftnofima |
language |
English |
description |
The present study examined the protective effects of water chloride (Cl−) towards nitrite toxicity in Atlantic salmon parr during 84‐day long nitrite exposure. Effects on growth, histology, blood indices and gene expression were studied at a fixed nominal Cl− concentration of 200 mg/L and at several water nitrite concentrations (0, 0.5, 2, 5 and 10 mg/L NO2−–N). The specific growth rate was significantly reduced during the first three weeks at a Cl:NO2−–N ratio of 21:1, suggesting the activation of coping mechanisms at the later stages of the experiment. No significant effect of nitrite on gill histology and mortality was found. Nitrite accumulated in plasma; however, a Cl:NO2−–N ratio of 104:1 or higher prevented nitrite entry. The concentration of NO2−–N in plasma was significantly reduced at the end of the study, supporting the hypothesis of coping mechanisms. Cystic fibrosis transmembrane conductance regulator (cftr)‐1 showed a significant up‐regulation at highest nitrite concentration on day 22, and in three of the highest exposure groups at the end of the experiment. Our findings suggest that a Cl:NO2−–N ratio above 104:1 should be maintained through episodes of nitrite accumulation in water during the production of Atlantic salmon parr. Effects of chronic sub‐lethal nitrite exposure at high water chloride concentration on Atlantic salmon (Salmo salar, Linnaeus 1758) parr submittedVersion |
format |
Article in Journal/Newspaper |
author |
Gutiérrez, Xavier Andrés Kolarevic, Jelena Takle, Harald Rune Bæverfjord, Grete Ytteborg, Elisabeth Terjesen, Bendik Fyhn |
spellingShingle |
Gutiérrez, Xavier Andrés Kolarevic, Jelena Takle, Harald Rune Bæverfjord, Grete Ytteborg, Elisabeth Terjesen, Bendik Fyhn Effects of chronic sub‐lethal nitrite exposure at high water chloride concentration on Atlantic salmon (Salmo salar, Linnaeus 1758) parr |
author_facet |
Gutiérrez, Xavier Andrés Kolarevic, Jelena Takle, Harald Rune Bæverfjord, Grete Ytteborg, Elisabeth Terjesen, Bendik Fyhn |
author_sort |
Gutiérrez, Xavier Andrés |
title |
Effects of chronic sub‐lethal nitrite exposure at high water chloride concentration on Atlantic salmon (Salmo salar, Linnaeus 1758) parr |
title_short |
Effects of chronic sub‐lethal nitrite exposure at high water chloride concentration on Atlantic salmon (Salmo salar, Linnaeus 1758) parr |
title_full |
Effects of chronic sub‐lethal nitrite exposure at high water chloride concentration on Atlantic salmon (Salmo salar, Linnaeus 1758) parr |
title_fullStr |
Effects of chronic sub‐lethal nitrite exposure at high water chloride concentration on Atlantic salmon (Salmo salar, Linnaeus 1758) parr |
title_full_unstemmed |
Effects of chronic sub‐lethal nitrite exposure at high water chloride concentration on Atlantic salmon (Salmo salar, Linnaeus 1758) parr |
title_sort |
effects of chronic sub‐lethal nitrite exposure at high water chloride concentration on atlantic salmon (salmo salar, linnaeus 1758) parr |
publishDate |
2019 |
url |
http://hdl.handle.net/11250/2616669 https://doi.org/10.1111/are.14226 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
2687-2697 50 Aquaculture Research |
op_relation |
Norges forskningsråd: 237856 Nofima AS: 11244 Norges forskningsråd: 186913 Aquaculture Research. 2019, 50 2687-2697. urn:issn:1355-557X http://hdl.handle.net/11250/2616669 https://doi.org/10.1111/are.14226 cristin:1711038 |
op_doi |
https://doi.org/10.1111/are.14226 |
container_title |
Aquaculture Research |
container_volume |
50 |
container_issue |
9 |
container_start_page |
2687 |
op_container_end_page |
2697 |
_version_ |
1766360582128140288 |