Prevalence estimates and risk factors for early childhood wheeze across europe: The europrevall birth cohort
Background Preschool wheeze is an important problem worldwide.No comparative population-based studies covering different countries have previously been undertaken.Objective T o assess the prevalence of early childhood wheeze across Europe and evaluate risk factors focusing on food allergy, breast fe...
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ftnkunivathens:oai:lib.uoa.gr:uoadl:3107403 2024-02-11T10:05:14+01:00 Prevalence estimates and risk factors for early childhood wheeze across europe: The europrevall birth cohort Selby, A. Munro, A. Grimshaw, K.E. Cornelius, V. Keil, T. Grabenhenrich, L. Clausen, M. Dubakiene, R. Fiocchi, A. Kowalski, M.L. Papadopoulos, N.G. Reche, M. Sigurdardottir, S.T. Sprikkelman, A.B. Xepapadaki, P. Mills, E.N.C. Beyer, K. Roberts1, G. 2018-01-01 https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3107403 Αγγλικά English eng uoadl:3107403 https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3107403 scientific_publication_article Επιστημονική δημοσίευση - Άρθρο Περιοδικού Scientific publication - Journal Article 2018 ftnkunivathens 2024-01-18T18:59:19Z Background Preschool wheeze is an important problem worldwide.No comparative population-based studies covering different countries have previously been undertaken.Objective T o assess the prevalence of early childhood wheeze across Europe and evaluate risk factors focusing on food allergy, breast feeding and smoke exposure.Methods I nfants from nine countries were recruited into the EuroPrevall birth cohort.At 12 and 24 months, data on wheeze, allergic signs/symptoms, feeding, smoke exposure, infections and day care attendance were collected using questionnaires.Poisson regression was used to assess risk factors for wheeze.Results 12 049 infants were recruited.Data from the second year of life were available in 8805 (73.1%).The prevalence of wheeze in the second year of life ranged from <2% in Lodz (Poland) and Vilnius (Lithuania) to 13.1% (95% CI 10.7% to 15.5%) in Southampton (UK) and 17.2% (95% CI 15.0% 19.5%) in Reykjavik (Iceland).In multivariable analysis, frequent lower respiratory tract infections in the first and second years of life (incidence rate ratio (IRR) 1.9 (95% CI 1.3 to 2.6) and 2.5 (95% CI 1.9 to3.4), respectively), postnatal maternal smoking (IRR 1.6, 95% CI 1.1 to 2.4), day care attendance (IRR 1.6, 95% CI 1.1 to 2.5) and male gender (IRR 1.3, 95% CI 1.0 to 1.7) were associated with wheeze.The strength of their association with wheeze differed between countries.Food allergy and breast feeding were not independently associated with wheeze.Conclusion T he prevalence of early childhood wheeze varied considerably across Europe.Lower respiratory tract infections, day care attendance, postnatal smoke exposure and male gender are important risk factors.Further research is needed to identify additional modifiable risk factors that may differ between countrie. © 2018 BMJ Publishing Group. All rights reserved. Article in Journal/Newspaper Iceland Pergamos - Library and Information Center of National and Kapodistrian University of Athens |
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Pergamos - Library and Information Center of National and Kapodistrian University of Athens |
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English |
description |
Background Preschool wheeze is an important problem worldwide.No comparative population-based studies covering different countries have previously been undertaken.Objective T o assess the prevalence of early childhood wheeze across Europe and evaluate risk factors focusing on food allergy, breast feeding and smoke exposure.Methods I nfants from nine countries were recruited into the EuroPrevall birth cohort.At 12 and 24 months, data on wheeze, allergic signs/symptoms, feeding, smoke exposure, infections and day care attendance were collected using questionnaires.Poisson regression was used to assess risk factors for wheeze.Results 12 049 infants were recruited.Data from the second year of life were available in 8805 (73.1%).The prevalence of wheeze in the second year of life ranged from <2% in Lodz (Poland) and Vilnius (Lithuania) to 13.1% (95% CI 10.7% to 15.5%) in Southampton (UK) and 17.2% (95% CI 15.0% 19.5%) in Reykjavik (Iceland).In multivariable analysis, frequent lower respiratory tract infections in the first and second years of life (incidence rate ratio (IRR) 1.9 (95% CI 1.3 to 2.6) and 2.5 (95% CI 1.9 to3.4), respectively), postnatal maternal smoking (IRR 1.6, 95% CI 1.1 to 2.4), day care attendance (IRR 1.6, 95% CI 1.1 to 2.5) and male gender (IRR 1.3, 95% CI 1.0 to 1.7) were associated with wheeze.The strength of their association with wheeze differed between countries.Food allergy and breast feeding were not independently associated with wheeze.Conclusion T he prevalence of early childhood wheeze varied considerably across Europe.Lower respiratory tract infections, day care attendance, postnatal smoke exposure and male gender are important risk factors.Further research is needed to identify additional modifiable risk factors that may differ between countrie. © 2018 BMJ Publishing Group. All rights reserved. |
format |
Article in Journal/Newspaper |
author |
Selby, A. Munro, A. Grimshaw, K.E. Cornelius, V. Keil, T. Grabenhenrich, L. Clausen, M. Dubakiene, R. Fiocchi, A. Kowalski, M.L. Papadopoulos, N.G. Reche, M. Sigurdardottir, S.T. Sprikkelman, A.B. Xepapadaki, P. Mills, E.N.C. Beyer, K. Roberts1, G. |
spellingShingle |
Selby, A. Munro, A. Grimshaw, K.E. Cornelius, V. Keil, T. Grabenhenrich, L. Clausen, M. Dubakiene, R. Fiocchi, A. Kowalski, M.L. Papadopoulos, N.G. Reche, M. Sigurdardottir, S.T. Sprikkelman, A.B. Xepapadaki, P. Mills, E.N.C. Beyer, K. Roberts1, G. Prevalence estimates and risk factors for early childhood wheeze across europe: The europrevall birth cohort |
author_facet |
Selby, A. Munro, A. Grimshaw, K.E. Cornelius, V. Keil, T. Grabenhenrich, L. Clausen, M. Dubakiene, R. Fiocchi, A. Kowalski, M.L. Papadopoulos, N.G. Reche, M. Sigurdardottir, S.T. Sprikkelman, A.B. Xepapadaki, P. Mills, E.N.C. Beyer, K. Roberts1, G. |
author_sort |
Selby, A. |
title |
Prevalence estimates and risk factors for early childhood wheeze across europe: The europrevall birth cohort |
title_short |
Prevalence estimates and risk factors for early childhood wheeze across europe: The europrevall birth cohort |
title_full |
Prevalence estimates and risk factors for early childhood wheeze across europe: The europrevall birth cohort |
title_fullStr |
Prevalence estimates and risk factors for early childhood wheeze across europe: The europrevall birth cohort |
title_full_unstemmed |
Prevalence estimates and risk factors for early childhood wheeze across europe: The europrevall birth cohort |
title_sort |
prevalence estimates and risk factors for early childhood wheeze across europe: the europrevall birth cohort |
publishDate |
2018 |
url |
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3107403 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
uoadl:3107403 https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3107403 |
_version_ |
1790602138501513216 |