Enzymatic synthesis of perillyl alcohol derivatives and investigation of their antiproliferative activity

• Main Authors: Xanthakis, E., Magkouta, S., Loutrari, H., Stamatis, H., Roussos, C., Kolisis, F.N.
• Format: Article in Journal/Newspaper
• Language: English
• Published: 2009
• Subjects: Almond; Antarc*; Antarctica
• Online Access: https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2981763

The monoterpene perillyl alcohol (POH), an intermediate in the plant terpenoid biosynthetic pathway, has well-established tumor chemopreventive and chemotherapeutic potential. We have previously shown that the primary hydroxyl group of POH is essential for its antitumor and anti-angiogenic activitie...