Activation of platelets and inflammatory cytokines in male participants of an Indian Antarctic expedition
Based on 12 male volunteers we investigated through blood samples at four distinct time-points if a sojourn of 90 days in the Antarctic environment induces or impels significant alterations in platelet activation and inflammatory cytokines. The levels of coagulation signatures in terms of platelet a...
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Format: | Article in Journal/Newspaper |
Language: | English |
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2019
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ftnipr:oai:nipr.repo.nii.ac.jp:00015610 2023-05-15T13:49:00+02:00 Activation of platelets and inflammatory cytokines in male participants of an Indian Antarctic expedition 2019-03 https://nipr.repo.nii.ac.jp/?action=repository_uri&item_id=15610 http://id.nii.ac.jp/1291/00015505/ en eng https://doi.org/10.1016/j.polar.2018.11.003 https://nipr.repo.nii.ac.jp/?action=repository_uri&item_id=15610 http://id.nii.ac.jp/1291/00015505/ Polar Science, 19, 146-150(2019-03) 18739652 Antarctica Platelets Inflammation Clotting time Stress Journal Article 2019 ftnipr https://doi.org/10.1016/j.polar.2018.11.003 2022-12-03T19:43:10Z Based on 12 male volunteers we investigated through blood samples at four distinct time-points if a sojourn of 90 days in the Antarctic environment induces or impels significant alterations in platelet activation and inflammatory cytokines. The levels of coagulation signatures in terms of platelet activation molecules, clotting time, clot rate, key inflammatory cytokines and coagulation-associated inflammatory markers were measured. Significant enhancement in the expression of platelet activation molecules and cytokines was observed with shortened clotting time, most prominent during the ship's approach to the continent. In conclusion, exposure to the Antarctic environment correlated with hyper activation of platelets and inflammatory cytokines, indicative of the pro-coagulative state. Article in Journal/Newspaper Antarc* Antarctic Antarctica Polar Science Polar Science National Institute of Polar Research Repository, Japan Antarctic The Antarctic Indian Polar Science 19 146 150 |
institution |
Open Polar |
collection |
National Institute of Polar Research Repository, Japan |
op_collection_id |
ftnipr |
language |
English |
topic |
Antarctica Platelets Inflammation Clotting time Stress |
spellingShingle |
Antarctica Platelets Inflammation Clotting time Stress Activation of platelets and inflammatory cytokines in male participants of an Indian Antarctic expedition |
topic_facet |
Antarctica Platelets Inflammation Clotting time Stress |
description |
Based on 12 male volunteers we investigated through blood samples at four distinct time-points if a sojourn of 90 days in the Antarctic environment induces or impels significant alterations in platelet activation and inflammatory cytokines. The levels of coagulation signatures in terms of platelet activation molecules, clotting time, clot rate, key inflammatory cytokines and coagulation-associated inflammatory markers were measured. Significant enhancement in the expression of platelet activation molecules and cytokines was observed with shortened clotting time, most prominent during the ship's approach to the continent. In conclusion, exposure to the Antarctic environment correlated with hyper activation of platelets and inflammatory cytokines, indicative of the pro-coagulative state. |
format |
Article in Journal/Newspaper |
title |
Activation of platelets and inflammatory cytokines in male participants of an Indian Antarctic expedition |
title_short |
Activation of platelets and inflammatory cytokines in male participants of an Indian Antarctic expedition |
title_full |
Activation of platelets and inflammatory cytokines in male participants of an Indian Antarctic expedition |
title_fullStr |
Activation of platelets and inflammatory cytokines in male participants of an Indian Antarctic expedition |
title_full_unstemmed |
Activation of platelets and inflammatory cytokines in male participants of an Indian Antarctic expedition |
title_sort |
activation of platelets and inflammatory cytokines in male participants of an indian antarctic expedition |
publishDate |
2019 |
url |
https://nipr.repo.nii.ac.jp/?action=repository_uri&item_id=15610 http://id.nii.ac.jp/1291/00015505/ |
geographic |
Antarctic The Antarctic Indian |
geographic_facet |
Antarctic The Antarctic Indian |
genre |
Antarc* Antarctic Antarctica Polar Science Polar Science |
genre_facet |
Antarc* Antarctic Antarctica Polar Science Polar Science |
op_relation |
https://doi.org/10.1016/j.polar.2018.11.003 https://nipr.repo.nii.ac.jp/?action=repository_uri&item_id=15610 http://id.nii.ac.jp/1291/00015505/ Polar Science, 19, 146-150(2019-03) 18739652 |
op_doi |
https://doi.org/10.1016/j.polar.2018.11.003 |
container_title |
Polar Science |
container_volume |
19 |
container_start_page |
146 |
op_container_end_page |
150 |
_version_ |
1766250385227382784 |