Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS
Per- and polyfluoroalkyl substances (PFAS) are a group of emerging substances that have proved to be persistent and highly bioaccumulative. They are broadly used in various applications and are known for their long-distance migration and toxicity. In this study, 65 recent specimens of a terrestrial...
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2022
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Online Access: | http://nora.nerc.ac.uk/id/eprint/531173/ https://nora.nerc.ac.uk/id/eprint/531173/1/N531173PP.pdf https://doi.org/10.1016/j.chemosphere.2021.131775 |
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ftnerc:oai:nora.nerc.ac.uk:531173 2023-05-15T16:33:28+02:00 Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS Androulakakis, Andreas Alygizakis, Nikiforos Gkotsis, Georgios Nika, Maria-Christina Nikolopoulou, Varvara Bizani, Erasmia Chadwick, Elizabeth Cincinelli, Alessandra Claßen, Daniela Danielsson, Sara Dekker, Rene W.R.J. Duke, Guy Glowacka, Natalia Jansman, Hugh A.H. Krone, Oliver Martellini, Tania Movalli, Paola Persson, Sara Roos, Anna O'Rourke, Emily Siebert, Ursula Treu, Gabriele van den Brink, Nico W. Walker, Lee Anthony Deaville, Rob Slobodnik, Jaroslav Thomaidis, Nikolaos S. 2022-01 text http://nora.nerc.ac.uk/id/eprint/531173/ https://nora.nerc.ac.uk/id/eprint/531173/1/N531173PP.pdf https://doi.org/10.1016/j.chemosphere.2021.131775 en eng Elsevier https://nora.nerc.ac.uk/id/eprint/531173/1/N531173PP.pdf Androulakakis, Andreas; Alygizakis, Nikiforos; Gkotsis, Georgios; Nika, Maria-Christina; Nikolopoulou, Varvara; Bizani, Erasmia; Chadwick, Elizabeth; Cincinelli, Alessandra; Claßen, Daniela; Danielsson, Sara; Dekker, Rene W.R.J.; Duke, Guy; Glowacka, Natalia; Jansman, Hugh A.H.; Krone, Oliver; Martellini, Tania; Movalli, Paola; Persson, Sara; Roos, Anna; O'Rourke, Emily; Siebert, Ursula; Treu, Gabriele; van den Brink, Nico W.; Walker, Lee Anthony; Deaville, Rob; Slobodnik, Jaroslav; Thomaidis, Nikolaos S. 2022 Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS. Chemosphere, 287, 131775. 11, pp. https://doi.org/10.1016/j.chemosphere.2021.131775 <https://doi.org/10.1016/j.chemosphere.2021.131775> Ecology and Environment Publication - Article PeerReviewed 2022 ftnerc https://doi.org/10.1016/j.chemosphere.2021.131775 2023-02-04T19:52:36Z Per- and polyfluoroalkyl substances (PFAS) are a group of emerging substances that have proved to be persistent and highly bioaccumulative. They are broadly used in various applications and are known for their long-distance migration and toxicity. In this study, 65 recent specimens of a terrestrial apex predator (Common buzzard), freshwater and marine apex predators (Eurasian otter, harbour porpoise, grey seal, harbour seal) and their potential prey (bream, roach, herring, eelpout) from northern Europe (United Kingdom, Germany, the Netherlands and Sweden) were analyzed for the presence of legacy and emerging PFAS, employing a highly sensitive liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) method. 56 compounds from 14 classes were measured; 13 perfluoroalkyl carboxylic acids (PFCAs), 7 perfluoroalkyl sulphonic acids (PFSAs), 3 perfluorooctane sulfonamides (FOSAs), 4 perfluoroalkylphosphonic acids (PFAPAs), 3 perfluoroalkylphosphinic acids (PFPi's), 5 telomer alcohols (FTOHs), 2 mono-substituted polyfluorinated phosphate esters (PAPs), 2 di-substituted polyfluorinated phosphate esters (diPAPs), 6 saturated fluorotelomer acids (FTAS), 3 unsaturated fluorotelomer acids (FTUAs), 2 N-Alkyl perfluorooctane sulfonamidoethanols (FOSEs), 3 fluorotelomer sulphonic acids (FTSAs), 2 perfluoroether carboxylic acids (PFECAs) and 1 chlorinated perfluoroether sulphonic acid (Cl-PFESA). All samples were lyophilized before analysis, in order to enhance extraction efficiency, improve the precision and achieve lower detection limits. The analytes were extracted from the dry matrices through generic methods of extraction, using an accelerated solvent extraction (ASE), followed by clean-up through solid phase extraction (SPE). Method detection limits and method quantification limits ranged from 0.02 to 1.25 ng/g wet weight (ww) and from 0.05 to 3.79 ng/g (ww), respectively. Recovery ranged from 40 to 137%. Method precision ranged from 3 to 20 %RSD. The sum of PFAS concentration in apex predators ... Article in Journal/Newspaper Harbour porpoise harbour seal Natural Environment Research Council: NERC Open Research Archive Chemosphere 287 131775 |
institution |
Open Polar |
collection |
Natural Environment Research Council: NERC Open Research Archive |
op_collection_id |
ftnerc |
language |
English |
topic |
Ecology and Environment |
spellingShingle |
Ecology and Environment Androulakakis, Andreas Alygizakis, Nikiforos Gkotsis, Georgios Nika, Maria-Christina Nikolopoulou, Varvara Bizani, Erasmia Chadwick, Elizabeth Cincinelli, Alessandra Claßen, Daniela Danielsson, Sara Dekker, Rene W.R.J. Duke, Guy Glowacka, Natalia Jansman, Hugh A.H. Krone, Oliver Martellini, Tania Movalli, Paola Persson, Sara Roos, Anna O'Rourke, Emily Siebert, Ursula Treu, Gabriele van den Brink, Nico W. Walker, Lee Anthony Deaville, Rob Slobodnik, Jaroslav Thomaidis, Nikolaos S. Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS |
topic_facet |
Ecology and Environment |
description |
Per- and polyfluoroalkyl substances (PFAS) are a group of emerging substances that have proved to be persistent and highly bioaccumulative. They are broadly used in various applications and are known for their long-distance migration and toxicity. In this study, 65 recent specimens of a terrestrial apex predator (Common buzzard), freshwater and marine apex predators (Eurasian otter, harbour porpoise, grey seal, harbour seal) and their potential prey (bream, roach, herring, eelpout) from northern Europe (United Kingdom, Germany, the Netherlands and Sweden) were analyzed for the presence of legacy and emerging PFAS, employing a highly sensitive liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) method. 56 compounds from 14 classes were measured; 13 perfluoroalkyl carboxylic acids (PFCAs), 7 perfluoroalkyl sulphonic acids (PFSAs), 3 perfluorooctane sulfonamides (FOSAs), 4 perfluoroalkylphosphonic acids (PFAPAs), 3 perfluoroalkylphosphinic acids (PFPi's), 5 telomer alcohols (FTOHs), 2 mono-substituted polyfluorinated phosphate esters (PAPs), 2 di-substituted polyfluorinated phosphate esters (diPAPs), 6 saturated fluorotelomer acids (FTAS), 3 unsaturated fluorotelomer acids (FTUAs), 2 N-Alkyl perfluorooctane sulfonamidoethanols (FOSEs), 3 fluorotelomer sulphonic acids (FTSAs), 2 perfluoroether carboxylic acids (PFECAs) and 1 chlorinated perfluoroether sulphonic acid (Cl-PFESA). All samples were lyophilized before analysis, in order to enhance extraction efficiency, improve the precision and achieve lower detection limits. The analytes were extracted from the dry matrices through generic methods of extraction, using an accelerated solvent extraction (ASE), followed by clean-up through solid phase extraction (SPE). Method detection limits and method quantification limits ranged from 0.02 to 1.25 ng/g wet weight (ww) and from 0.05 to 3.79 ng/g (ww), respectively. Recovery ranged from 40 to 137%. Method precision ranged from 3 to 20 %RSD. The sum of PFAS concentration in apex predators ... |
format |
Article in Journal/Newspaper |
author |
Androulakakis, Andreas Alygizakis, Nikiforos Gkotsis, Georgios Nika, Maria-Christina Nikolopoulou, Varvara Bizani, Erasmia Chadwick, Elizabeth Cincinelli, Alessandra Claßen, Daniela Danielsson, Sara Dekker, Rene W.R.J. Duke, Guy Glowacka, Natalia Jansman, Hugh A.H. Krone, Oliver Martellini, Tania Movalli, Paola Persson, Sara Roos, Anna O'Rourke, Emily Siebert, Ursula Treu, Gabriele van den Brink, Nico W. Walker, Lee Anthony Deaville, Rob Slobodnik, Jaroslav Thomaidis, Nikolaos S. |
author_facet |
Androulakakis, Andreas Alygizakis, Nikiforos Gkotsis, Georgios Nika, Maria-Christina Nikolopoulou, Varvara Bizani, Erasmia Chadwick, Elizabeth Cincinelli, Alessandra Claßen, Daniela Danielsson, Sara Dekker, Rene W.R.J. Duke, Guy Glowacka, Natalia Jansman, Hugh A.H. Krone, Oliver Martellini, Tania Movalli, Paola Persson, Sara Roos, Anna O'Rourke, Emily Siebert, Ursula Treu, Gabriele van den Brink, Nico W. Walker, Lee Anthony Deaville, Rob Slobodnik, Jaroslav Thomaidis, Nikolaos S. |
author_sort |
Androulakakis, Andreas |
title |
Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS |
title_short |
Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS |
title_full |
Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS |
title_fullStr |
Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS |
title_full_unstemmed |
Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS |
title_sort |
determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from northern europe by lc-ms/ms |
publisher |
Elsevier |
publishDate |
2022 |
url |
http://nora.nerc.ac.uk/id/eprint/531173/ https://nora.nerc.ac.uk/id/eprint/531173/1/N531173PP.pdf https://doi.org/10.1016/j.chemosphere.2021.131775 |
genre |
Harbour porpoise harbour seal |
genre_facet |
Harbour porpoise harbour seal |
op_relation |
https://nora.nerc.ac.uk/id/eprint/531173/1/N531173PP.pdf Androulakakis, Andreas; Alygizakis, Nikiforos; Gkotsis, Georgios; Nika, Maria-Christina; Nikolopoulou, Varvara; Bizani, Erasmia; Chadwick, Elizabeth; Cincinelli, Alessandra; Claßen, Daniela; Danielsson, Sara; Dekker, Rene W.R.J.; Duke, Guy; Glowacka, Natalia; Jansman, Hugh A.H.; Krone, Oliver; Martellini, Tania; Movalli, Paola; Persson, Sara; Roos, Anna; O'Rourke, Emily; Siebert, Ursula; Treu, Gabriele; van den Brink, Nico W.; Walker, Lee Anthony; Deaville, Rob; Slobodnik, Jaroslav; Thomaidis, Nikolaos S. 2022 Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS. Chemosphere, 287, 131775. 11, pp. https://doi.org/10.1016/j.chemosphere.2021.131775 <https://doi.org/10.1016/j.chemosphere.2021.131775> |
op_doi |
https://doi.org/10.1016/j.chemosphere.2021.131775 |
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Chemosphere |
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287 |
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131775 |
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1766023153305255936 |